44,636 papers found

BACKGROUND: Choirs are an important source of wellbeing for people experiencing palliative and end-of-life care. Threshold choirs are an innovation that could be more widely introduced, as hospital and palliative care settings have become more open to community input. AIMS: Before such choirs are recommended and encou…

Hansen Disease (leprosy) is a chronic inflammatory infectious disease that primarily targets skin, nerves and other internal organs (testis, liver etc.) caused by the acid fast intracellular bacilli, Mycobacterium leprae. Clinical presentation occurs with a wide spectrum including hypo pigmented anaesthetic patches, ra…

The complement system is crucial for maintaining immunological homeostasis in the liver, playing a significant role in both innate and adaptive immune responses. Dysregulation of this system is closely linked to the pathogenesis of various liver diseases. Modulating the complement system can affect the progression of t…

Parotid metastases (PMs) that originate from thyroid carcinomas (TCs) are extremely rare, and many questions about their diagnosis and management remain unanswered. Of the 15,780 patients with TC that we had prospectively recorded in our institutional databases between 1996 and 2015, we retrospectively retrieved only t…

Numerous studies have investigated association of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with lung cancer (LC) susceptibility in Chinese; however, the findings are inconsistent. Therefore, we performed a meta-analysis. PubMed, ISI Web of Knowledge, Chinese National Knowledge Infrastructure, and…

Serotonin reuptake inhibitors (SRIs) are occasionally associated with sensory symptoms, which are one of the less recognized adverse effects. A PUBMED search supplemented with manual search was made to review the relevant literature. Anesthesia, paresthesia, and mastalgia have been reported to occur with this group of…

OBJECTIVE: Dementia is an age-related progressive neurodegenerative disorder afflicting about 5% of the world's population, and it is expected to grow dramatically in the future keeping in view our ageing society. Currently available medications appear to be able to produce moderate symptomatic benefits but do not to s…

BACKGROUND: Perineural spread of head and neck tumors is linked to a worse chance of survival as well as a higher risk of local recurrence and metastasis. Particle emission tomography/computed tomography (PET/CT) using 2-[fluorine-18]fluoro-2-deoxy-d-glucose (FDG) is part of the work-up and follow-up of many afflicted…

BACKGROUND: Tunneled central venous catheters (CVCs) are the cornerstone of modern oncologic practice. Establishing best practices for catheter management in children with cancer is essential to optimize care, but few guidelines exist to guide placement and management. OBJECTIVES: To address four questions: 1) Does ca…

BACKGROUND: We conducted a meta-analysis to comprehensively assess the predictive role of MYC, BCL2, and BCL6 genetic alterations and protein expression in PCNSL for clinical application. METHODS: A systematic retrieval was performed on PubMed, Embase, the Cochrane library, Web of Science, Scopus, and 2 Chinese databa…

PURPOSE: To systematically review the literature and perform a meta-analysis assessing the efficacy and safety of N-butyl cyanoacrylate (NBCA) glue diluted with Lipiodol for vascular embolization. METHODS: A systematic search of MEDLINE/PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials (CENTRAL) i…

BACKGROUND: Late-onset sepsis is associated with increased rates of mortality and morbidity in newborn infants, in addition to poorer long-term developmental outcomes and increased length of stay and hospital costs. Central line-associated blood stream infection (CLABSI) is the most common cause of late-onset sepsis in…

BACKGROUND: High-frequency ultrasound (HFUS) is a versatile but underutilised imaging modality in breast surgery. Its high resolution offers a unique imaging perspective when compared to other modalities such as magnetic resonance imaging (MRI) and conventional, lower frequency ultrasound (<10 MHz). This narrative revi…

PURPOSE: This integrative review aimed to examine the application and outcomes of project-based learning (PjBL) in pediatric nursing education and to identify its key characteristics. METHODS: Following the integrative review methodology proposed by Whittemore and Knafl, a comprehensive literature search was conducted…

OBJECTIVES: Dexmedetomidine has been increasingly used as an alternative sedative agent during bronchoscopy, but its comparative efficacy and safety remain unclear. This systematic review and meta-analysis aimed to assess the effectiveness and safety of dexmedetomidine compared with other sedative agents in adult bronc…

PURPOSE OF REVIEW: Horseshoe kidney (HSK) is a renal congenital abnormality characterized by the fusion of the lower poles of both kidneys via an isthmus. In robotic assisted surgery, HSK presents challenges due to its atypical anatomy, including aberrant vasculature and restricted renal mobility, complicating operativ…

AIM: This review synthesizes research on nursing students' perceptions of dignity shaped by education and clinical experiences. BACKGROUND: Respect for human dignity is central to nursing ethics. While dignity is well studied in patient care, less focus has been given to how nursing students perceive and experience di…

INTRODUCTION: Artificial intelligence (AI) prognostic models in endodontics may estimate treatment outcomes, but single-pathway prediction does not provide comparative decision support for failed cases in which nonsurgical retreatment (NS-ReTx) and endodontic microsurgery (EMS) may both be considered. This scoping revi…

Family caregiving has been central to U.S. eldercare, supported by federal policies. However, recent shifts towards neoliberalism, devolution of aging policy, rising chronic illnesses, and increasing social isolation have spurred interest in intergenerational communities.This study explores these models, assessing thei…

Co-dependency is a contested construct, applied to a broad range of relational difficulties. Despite its relevance, the term remains conceptually fragmented. This limits research development and clinical recognition, hindering the creation of effective interventions. An integrative systematic review is therefore needed…