44,636 papers found

OBJECTIVE: This systematic review supported development of a conceptual framework for user-centered process evaluations of web-based diet and exercise programs for older adults with chronic disease. METHODS: Four databases were utilized: PubMed, Embase, Business Source Premier, and ABI/Inform. Primary search terms wer…

: Zygomatic implants (ZIs) were initially pioneered by Brånemark to rehabilitate patients suffering from destructive diseases through original surgical technique (OST). Subsequently, other techniques were proposed, such as the zygomatic anatomy-guided approach (ZAGA). This umbrella review was conceived to quantify…

Environmental Health Literacy (EHL) empowers individuals and communities to understand and make informed decisions about health and the environment. This study uses bibliometric indicators to map the field, identifying patterns, emerging trends, and gaps that offer opportunities for future research. We analyze 152 arti…

Maternal nutrition and gut microbiome composition are central regulators of fetal development and perinatal outcomes, modulating immune signaling, oxidative balance, and epigenetic programming. The authors searched PubMed, Scopus, the Cochrane Library, and Web of Science for full-text, peer-reviewed articles published…

Problem-Based Learning (PBL) has emerged as a promising educational approach for developing Evidence-Based Practice (EBP) competencies in nursing and midwifery education. PBL is a student-centered educational approach that uses authentic, ill-structured clinical problems as the starting point for learning, where small…

BACKGROUND: Health literacy and numeracy are broad terms that relate to a patient's understanding of their health information. While there is a substantial amount of research on this topic in a general sense as well as in relation to how deficiencies in these skills impact patients' understanding of laboratory results,…

OBJECTIVE: The relationship between pre-stroke frailty and clinical outcomes remains unclear. This systematic review aimed to examine the association of pre-stroke frailty with mortality, length of stay (LOS), and functional outcomes in people with stroke. METHODS: We used several databases, including PubMed, EMBASE,…

BACKGROUND: This study aims to evaluate the association between retinal ischemic perivascular lesions (RIPLs) detected by optical coherence tomography (OCT) and the risk of all-cause cardiovascular morbidity. METHODS: A systematic review and meta-analysis were performed. PubMed MEDLINE, Scopus, and Cochrane CENTRAL wer…

INTRODUCTION: Delayed rewards discounting describes the tendency to choose a smaller immediate rewards instead of a larger delayed rewards. Considering the central role of impulsivity in models accounting for criminal conduct in general and violent behavior, the relationship between delayed rewards discounting and crim…

Maximal voluntary contraction (MVC) is a key determinant of human strength, mobility and functional performance. While muscle morphology contributes to MVC force, neural factors-particularly cortical and spinal excitability and inhibition-play a central role in motor unit recruitment. Despite its importance, the neurop…

INTRO: Individuals with chronic musculoskeletal pain (CMP) and high pain catastrophizing demonstrate functional and structural brain changes via functional magnetic resonance imaging that may serve as useful neural correlates. Yet, few studies take advantage of electroencephalography (EEG), a more cost effective and ac…

BACKGROUND: The revised Dutch Multidisciplinary Guideline for Depression recommends liothyronine augmentation to selective serotonin reuptake inhibitors (SSRIs) as one of several third-line treatment options for moderate to severe depression, the others being lithium and atypical antipsychotics. The guideline refers to…

Obstructive sleep apnea (OSA) is a common sleep disorder characterized by recurrent upper airway obstructions, leading to substantial health burdens and socioeconomic costs. This study aimed to identify Hypoxia and Mitophagy-Related Differentially Expressed Genes (HMRDEGs) and evaluate their potential as biomarkers and…

BACKGROUND: The characteristics of medical data in Precision Medicine (PM), the challenges related to their storage and retrieval, and the effective facilities to address these challenges are importantly considered in implementing PM. For this purpose, a secured and scalable infrastructure for various data integration…

UNLABELLED: . Indications to the use of subcutaneous route for fluids and drugs administration: a literature review. INTRODUCTION: Hypodermoclysis is a practice valued in recent years for its safety. However, it continues to be underutilized. OBJECTIVE: To analyze the most recent evidences on the use of hypodermoclys…

BACKGROUND: Neuropsychiatric disorders make up 14% of the global disease burden and are the leading cause of disability from noncommunicable diseases worldwide. The primary treatment for these disorders is drug therapy. Nonetheless, these therapies do not work completely for most patients, and even with attempts to cre…

INTRODUCTION: Perioperative hypertension is a common occurrence in anesthetic practice, potentially leading to cardiac complications resulting in unfavorable patient outcomes. Clevidipine emerges in the current drug scenario as an antihypertensive agent with advantageous properties like ultra-short half-life, titratabl…

OBJECTIVE: Periprosthetic joint infection (PJI) is the most feared complication after prosthesis implantation, especially in the oncological population. Anti-microbial coatings are a new potential strategy to reduce this infection risk further. This study aims to provide an overview of the coating technologies currentl…

The widespread implementation of intrathecal infusion systems (IIS) in managing chronic pain underscores the pivotal role of family caregivers in ensuring effective treatment outcomes and enhancing patients' quality of life. We conducted a comprehensive literature search across databases including PubMed, Medline, and…

Neuropathic pain causes tremendous biological and psychological suffering to patients worldwide. Environmental enrichment (EE) is a promising non-pharmacological strategy with high cost-effectiveness to reduce neuropathic pain and support rehabilitation therapy. Three researchers reviewed previous studies to determine…