98,296 papers found

OBJECTIVE: The study was conducted to estimate the effect of abnormal uterine bleeding on health care use. STUDY DESIGN: Data were taken from the National Health Interview Survey 1999, a nationwide representative sample of the civilian noninstitutionalized population of the United States. The participants who were eli…

For many years, surgery has been considered the best treatment modality for resectable nonsmall cell lung cancer. However, survival has not increased over the last few decades. The reported 5-year survival rates for the early stages (stage I and II) show failures of 35 to 65%. Therefore, a combined modality approach ha…

Landfill leachate is a complex wastewater which the composition and concentration of contaminants are influenced by the type of waste deposited and the age of landfill. In the last years, several processes or process combinations were developed and tested to reach requirements for the discharge of leachate. Among the n…

Cryptococcal meningitis is one of the most frequent forms of meningoencephalitis in AIDS patients. Before the introduction of triazole antibiotics like difluconazole, the frequency of this meningitis among AIDS patients was 5-10%, yet declined during the last years. Clinically, nonspecific signs of a meningeal inflamma…

The aim of this study was to develop a model to predict individual subject disease trajectories including parameter uncertainty and accounting for missing data in rare neurological diseases, showcased by the ultra-rare disease Autosomal-Recessive Spastic Ataxia Charlevoix Saguenay (ARSACS). We modelled the change in SA…

The incidence of major osteoporotic fractures has declined in men and women in Western countries over the last two decades. Although fracture risk is higher in persons with diabetes mellitus, trends of fractures remain unknown in men and women with diabetes. We investigated the trends in fracture incidence rates (IRs)…

Background The burden of cardiovascular disease is increasing, with many people treated for multiple cardiovascular conditions. We examined persistence and adherence to medicines for cardiovascular disease treatment or prevention in Australia. Methods and Results Using national dispensing claims for a 10% random sample…

To investigate the pathogen composition, initial anti-infectives and pathogen coverage, and trends over the last 5 years in children with septic shock in pediatric intensive care unit (PICU).The single-center retrospective study included 257 children with septic shock who were admitted to PICU of Beijing Children's Hos…

PURPOSE: Craniopharyngiomas are nonmalignant sellar and parasellar tumors exhibiting a bimodal age distribution. While the outcomes following treatment in patients with childhood-onset craniopharyngiomas are well characterized, similar information in adult-onset craniopharyngiomas is limited. We aimed to describe the l…

BACKGROUND: We report prevalence and incidence of drug use initiation in Australian gay and bisexual men (GBM) participating in an online cohort study. METHODS: Between September 2014 and June 2015, 1,710 GBM were enrolled in the Following Lives Undergoing Change Study and followed-up six monthly. Participants were as…

BACKGROUND: The outcome of orthotopic liver transplantation (OLT) for hepatocellular carcinoma (HCC) is excellent if it is performed within the Milan criteria (ie, single tumor less than 5 cm or 3 tumors less than 3 cm each one and no macrovascular invasion). However, after a few studies, it has become possible to have…

INTRODUCTION: This is a prospective study of adolescent patients in whom idiopathic thoracic scoliosis was corrected by short anterior fusion through a mini-open thoracotomy approach. Clinical, radiological and pulmonary function results of minimal 2-year (2-6) follow-up are presented. MATERIALS AND METHODS: Consecuti…

BACKGROUND: Zenker diverticulum (ZD) is a pseudodiverticulum and usually affects males in the 6th-9th decade of life, symptoms include dysphagia, regurgitation, chronic cough, aspiration, halitosis and weight loss. Surgery has been the mainstay treatment of symptomatic ZD and can be divided into external and intralumin…

OBJECTIVE: To present the use of autologous buccal mucosa graft (BMG) in the treatment of recurrent vesicovaginal fistula (VVF). CASE REPORTS: In 2011, two women, aged 45 years and 56 years, were admitted due to recurrent VVF. Both women had previously undergone abdominal hysterectomies for benign conditions and, subs…

Laparoscopic colon resection has established its role as a minimally invasive approach to colorectal diseases. Better long-term survival rate is suggested to be achievable with this approach in colon cancer patients, whereas some doubts were raised about its safety in rectal cancer. Here we report on our single centre…

BACKGROUND: In the last decade, several investigators have reported that double etched implants have achieved excellent results. However, no report regarding double etched implants inserted into fresh frozen bone is available. AIMS: We planned to perform a retrospective study on double etched implants inserted into fr…

Despite being predicted to be stereoelectronically favorable by the Baldwin rules, efficient formation of a C-C bond through a 5-endo-dig radical cyclization remained unknown for more than 40 years. This work reports a remarkable increase in the efficiency of this process upon beta-Ts substitution, which led to the dev…

Hepatitis C is a notifiable disease in Poland since 1997. The increasing trend in incidence over the last four years may be explained by continuous improvement of diagnosis and notification. In the year 2001, for the first time since 1997, a number of cases and an incidence of hepatitis C was lower than in preceding ye…

OBJECTIVE: We report on two years of clinical experience with a frameless Computer Aided Surgery system developed in Bern, Switzerland. MATERIAL AND METHODS: Our navigation system is based on a preoperative computer-tomography (CT) scan (without markers) and an intraoperative optical tracking of head movements and of…

There have been few reports about the frequency of multiple sclerosis (MS) in Spain. We undertook a prevalence study in the province of Teruel, which is served by two hospitals as referral centres for a population of 143,680. We found a total of 46 patients who fulfilled Poser's criteria for clinically definite or prob…