392,037 papers found

This study analyzes 1,000 meta-analyses drawn from 10 disciplines-including medicine, psychology, education, biology, and economics-to document and compare methodological practices across fields. We find large differences in the size of meta-analyses, the number of effect sizes per study, and the types of effect sizes…

INTRODUCTION: We evaluated the relative effects of newer versus older medications for neonatal conditions and trends in margin of superiority across generations. MATERIALS AND METHODS: We assessed network meta-analyses (NMAs) on neonatal pharmacological interventions identified from MEDLINE, Cochrane, and PROSPERO. In…

As evidence-based practice has become an important issue in healthcare settings, the educational needs for knowledge and skills for the generation and utilization of healthcare evidence are increasing. Systematic review (SR), a way of evidence generation, is a synthesis of primary scientific evidence, which summarizes…

Systematic reviews are an ideal way of summarizing evidence from primary studies. While systematic reviews of randomized trials are broadly used to summarize benefits and harms of interventions, systematic reviews of observational studies are useful to summarize data on prevalence of risk factors in a population, distr…

We describe a standardised mean difference statistic (d) for single-case designs that is equivalent to the usual d in between-groups experiments. We show how it can be used to summarise treatment effects over cases within a study, to do power analyses in planning new studies and grant proposals, and to meta-analyse eff…

This paper introduces an interactive Shiny web application designed to facilitate bidirectional statistical inference by allowing users to derive p-values from reported confidence intervals and vice versa. The tool serves as a practical resource for researchers, students, and reviewers aiming to verify or reconstruct s…

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Flores-Ferreyra, B. I., Argueta-Figueroa, L., Torres-Rosas, R., Carrasco-Gutiérrez, R. G., Casillas-Santana, M. A., & de los Angeles Moyaho-Bernal, M. (2024). Dental human enamel wear caused by ceramic antagonists: A systematic review and network meta-analysis. Journal…

ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Schiegnitz E, Reinicke K, Sagheb K, König J, Al-Nawas B, Grötz KA. Dental implants in patients with head and neck cancer-A systematic review and meta-analysis of the influence of radiotherapy on implant survival. Clinical oral implants research. 2022 Oct;33(10):967…

Amid rising national rates of childhood depression and anxiety,the development and accessibility of therapeutic psychosocial interventions for children have taken on paramount importance. Given the limited bandwidth of the existing clinical mental health services nationally, there is also an imperative to integrate the…

Many researchers rely on meta-analysis to summarize research evidence. However, there is a concern that publication bias and selective reporting may lead to biased meta-analytic effect sizes. We compare the results of meta-analyses to large-scale preregistered replications in psychology carried out at multiple laborato…

Guided bone-regeneration techniques use either resorbable or nonresorbable membrane. Ideal membrane material should be biocompatible with tissue integration, be able to create and maintain space, be occlusive with selective permeability, and have good handling properties. Commercially available nonresorbable membranes…

A discrete random effects model (Lan and Pinheiro, 2012) was proposed recently for multiregional clinical trials for continuous responses. This article elucidates further the application of this model to time-to-event and binary responses. We provide some guidelines on how to design multiregional trials and also show h…

Translational research of time-series of gene-expression microarray datasets makes use on gene expression profiles that have been obtained at different points in time. Our web-based multi-user program helps a researcher find temporal patterns like peaks in large pre-selected microarray data sets that include data from…

H. pylori is a definite carcinogen of gastric cancer. Animal studies have revealed that primary prevention of gastric cancer by H. pylori eradication is more effective as the duration between H. pylori infection and H. pylori eradication is decreased. In human, the cohort studies showed H. pylori eradication reduced th…