5,083,124 papers found

Systematic reviews have become a common method of synthesizing literature to examine the comparative effectiveness of medical interventions. Groups such as the Cochrane Collaboration and the U.S. Agency for Healthcare Research and Quality (AHRQ) conduct dozens of such reviews each year. However, these documents are oft…

BACKGROUND AND OBJECTIVES: Methods to identify studies for systematic reviews of diagnostic accuracy are less well developed than for reviews of intervention studies. This study assessed (1) the sensitivity and precision of five published search strategies and (2) the reliability and accuracy of reviewers screening the…

OBJECTIVE: To identify strategies for retrieval and evaluation of systematic reviews from a management perspective. STUDY DESIGN: Review of available literature and resources on systematic reviews. METHODS: From published literature on evidence-based medicine and systematic review, we identified resources and adapted…

OBJECTIVE: The objective of this review is to investigate the experiences of working as an early career allied health professional or doctor, and the factors that influence this experience in rural or remote environments. INTRODUCTION: Recruitment and retention of health professionals in rural and remote areas is chal…

OBJECTIVE: The objective of this scoping review is to examine and map interventions of palliative rehabilitation that are implemented and evaluated in palliative care. INTRODUCTION: Palliative rehabilitation is defined as the process of helping individuals with a progressive, often advanced or incurable disease reach…

BACKGROUND: Growing body of scientific researches in recent years have suggested the promising effect of meditation on improving cognitive impairment of Alzheimer disease (AD) and mild cognitive impairment (MCI). This paper aims to provide a protocol for systematic review to evaluate the efficacy of meditation on cogni…

BACKGROUND: Machine learning, a subset of artificial intelligence, is a set of models and methods that can automatically detect patterns in vast amounts of data, extract information and use it to perform various kinds of decision-making under uncertain conditions. This can assist surgeons in clinical decision-making by…

BACKGROUND: Artemisinin was discovered to be highly effective antimalarial drugs shortly after the isolation of the parent artemisinin in 1971 in China. It is derived from extracts of sweet wormwood (Artemisia annua) and are well established for the treatment of malaria. Recently, artemisinin has been shown that it mig…

The purpose of the paper is to discuss the formidable challenges to community reentry and reintegration faced by U.S. prison inmates with serious mental illness and to describe various strategies for improving transitional services for these individuals. We review epidemiologic data supporting the high prevalence of se…

REVIEW OBJECTIVE: The objective of this review is to identify the effectiveness of patient education for orthopedic surgery patients. More specifically, the objectives are to identify the effectiveness of patient education on:length of staysatisfactionpain levelcost of carefunctional abilitiesknowledgeanxietyquality of…

INTRODUCTION: Decision coaching is a non-directive approach to support patients to prepare for making health decisions. It is used to facilitate patients' involvement in informed values-based decision-making and use of evidence-based health information. A recent systematic review revealed low certainty evidence for its…

BACKGROUND: Meta-analyses are on top of the evidence-based medicine pyramid, yet many of them are not completed after they are begun. Many factors impacting the publication of meta-analysis works have been discussed, and their association with publication likelihood has been investigated. These factors include the type…

INTRODUCTION: Economic evaluations conducted alongside clinical trials play a key role in informing healthcare decision-making. While structured validation frameworks are well established for model-based economic evaluations, there is no agreed approach to validating trial-based economic evaluations. Validation activit…

BACKGROUND: Bioterrorism involves the intentional release of biological agents capable of causing mass casualties, public health emergencies, and societal disruption. As frontline healthcare providers, nurses play a critical role in early detection, isolation, emergency care, and surveillance. However, substantial gaps…

BACKGROUND: Disability is widely acknowledged as a major contributor to depression, which is a prevalent mental health condition that profoundly affects individuals, especially those with visual impairments. OBJECTIVES: This develops a protocol for a systematic review and meta-analysis aim to examine the prevalence an…

INTRODUCTION: Dengue fever is a major global public health challenge caused by the Arbovirus and transmitted by Aedes mosquitoes. The increasing incidence of dengue, particularly in the Southeast Asia (SEA) region, including Malaysia, highlights the urgent need for a comprehensive understanding of dengue molecular epid…

BACKGROUND: Infection is a common problem and a major cause of morbidity and mortality for patients in intensive care units (ICUs). According to published meta-analyses, oral care has been found to reduce the risk of nosocomial pneumonia, and has been recommended to improve the oral environment for patients in ICUs. Ho…

BACKGROUND: Corneal transplantation is the most frequently performed transplantation in the UK. Despite this, the therapeutic value of matching human leukocyte antigen (HLA) subtypes for transplanted corneas remains controversial. Ocular immune privilege was originally deemed to render matching unnecessary; however, mo…

BACKGROUND: Antimicrobial resistance (AMR) is an escalating global health issue with complex and dynamic interdependencies, high uncertainty and decision stakes, multiple drivers and stakeholders with diverse values and interests, and various aspects and outcomes. Addressing and combating this critical global challenge…

BACKGROUND: Studies on several preclinical models of type 2 diabetes mellitus have been conducted to establish the hypoglycemic activity of Momordica charantia L. Concerned with appropriateness of these models, we designed a systematic review to establish the efficacy and safety of M. charantia L. in preclinical models…