44,632 papers found

Primary hyperhidrosis is termed as excessive sweating exceeding the physiological needs of thermoregulation. This review provides an updated overview focusing on epidemiology, quality of life, pathophysiology, economic impacts, diagnostic approaches and current management strategies. A literature search was conduc…

Numerous plants are significant sources of bioactive chemicals with diverse therapeutic efficacy against numerous cancer types. Since ancient times, numerous plant types and their phytochemicals have been used for traditional and contemporary medicinal applications. Artepillin C (AC) is a biologically active phenolic c…

Single coronary artery (SCA) is a rare and anatomically heterogeneous congenital coronary anomaly in which the entire coronary circulation arises from a single aortic ostium. Its clinical significance depends on the ostial and proximal morphology, coronary course, associated coronary disease, symptoms and, where indica…

INTRODUCTION: Microneedles (MNs) have emerged as a versatile platform for transdermal delivery, enabling minimally invasive administration of small molecules and biologics. As their performance is fundamentally determined by material properties, continuous innovation in MN materials has been central to the evolution of…

BACKGROUND: Dysmenorrhea is a prevalent gynecological condition that significantly impacts the daily functioning and quality of life of women. No true national prevalence has been reported in India. The objective of this review was to determine the prevalence of dysmenorrhea and associated risk factors among Indian stu…

Among hematological malignancies, lymphoma is associated with an increased incidence of venous thromboembolism (VTE) ranging between 4 and 12%. Although Khorana score was validated for stratifying VTE risk in cancer, its discrimination reliability in lymphoma is reduced by the lack of specific predictors. The aim of th…

Impulse control disorders (ICDs) are a common non-motor complication in Parkinson's disease (PD) patients with multiple negative consequences for the individual and caregivers. Although ICDs are strongly linked to dopaminergic therapy, particularly dopamine agonists, only a percentage of patients develop these behavior…

The intricate crosstalk between probiotics and the host immune system is increasingly recognized as a central determinant of mucosal integrity, resistance to infection, and systemic homeostasis. This narrative review synthesizes current evidence identified through comprehensive searches of major scientific databases, i…

INTRODUCTION: High-throughput screening (HTS) has been central to antibacterial drug discovery for decades, identifying active compounds from large libraries. Advances in screening methodologies and compound availability have extended HTS from large organizations to smaller biotech and academic groups. Despite increase…

Knee osteoarthritis (OA) is a chronic, multifactorial joint disorder involving cartilage degeneration, subchondral bone changes, synovial inflammation, and neuromuscular dysfunction. Exercise is first-line therapy, yet heterogeneity in modalities, dosing, and delivery limits practical guidance. A narrative review was c…

BACKGROUND: Ghrelin, a brain-intestinal hormone, is a growth hormone (GH) secretagogue. Because it regulates appetite and is secreted most prominently before meals, it is often described as a "hunger hormone". It consists of 28 amino acids. Given the connection between nutritional status and energy metabolism, it sugge…

Social determinants of health (SDH) account for 50% of the variance in health outcomes and significantly contribute to health disparities. Proven strategies to address SDH in practice require interprofessional collaboration and community partnerships. Health professions students need to understand how to work in an int…

Contrast-enhanced ultrasound (CEUS) has emerged as a promising imaging modality in obstetrics, offering new insights into placental and maternal vascular function. We conducted a systematic review, registered in PROSPERO (CRD42024508860), to summarize the current clinical and research applications of CEUS during pregna…

This review synthesizes in silico evidence on the toxicological effects of microplastics (MPs) and nanoplastics (NPs) in zebrafish (). With the increasing prevalence of these pollutants in aquatic ecosystems, evaluating their molecular impacts is essential for risk assessment. We systematically mined toxicogenomic stud…

Chronic wounds are a growing healthcare challenge, with infections being major complications that delay healing. Biofilms are structured microbial communities encased in extracellular polymeric substances. Biofilms confer antimicrobial resistance, promote inflammation, and protect pathogens from host defenses. These me…

IntroductionCardiopulmonary bypass (CPB) plays a central role in pediatric cardiac surgery, yet standardized quality indicators (QIs) specific to pediatric practice remain underutilized across institutions.MethodsA comprehensive review of literature from 2010 to 2025 was conducted using PubMed, Embase, and the Cochrane…

Cranial neuropathy is a commonly encountered condition with various underlying etiologies. While carotid artery dissection (CAD) is a well-recognized cause of ischemic stroke, CAD-related cranial neuropathy is rare and poorly characterized. We have conducted a comprehensive review of the published literature to better…

PURPOSE: This meta-review of qualitative studies aims to explore the experiences and needs of family members following perinatal infant deaths. DESIGN: A qualitative meta-synthesis was conducted. DATA SOURCES: Four databases, PubMed, CINAHL, EMBASE, and Web of Science, were searched from inception through November 20…

The scope of this article is to identify adolescents' social representations of the body and how the issue of black bodies has been discussed. This is a systematic review whose searches took place in August 2023 in PubMed/MEDLINE, SciELO, Scopus, Web of Science, PsycInfo, PePSIC, BVS, and in the BDTD and OATD portals.…

OBJECTIVES: We reviewed asthma coexistence and the selection of biologic therapies in CRSwNP Management. METHODS: The literature review utilized Google and Google Scholar, in addition to PubMed, EBSCO, and Proquest Central at Kırıkkale University. We searched for " CRSwNP", "asthma", "biologic therapies",…