42,213 papers found

Several randomized controlled trials (RCTs) have examined the influence of oral chlorhexidine (CHX) in preventing nosocomial lower respiratory tract infection (LRTI). Most have failed to demonstrate a reduction in the incidence of LRTI. The present meta-analysis summarizes the effect of oral CHX on the development of L…

AIM: The purpose of this paper is to review and analyze the published literature on the use of three-dimensional (3DUS) and four-dimensional (4DUS) ultrasound in perinatal medicine. METHODS: We systematically searched Medline through PubMED (January 2000-January 2006), including EMBASE/Excerpta Medica database as well…

OBJECTIVE: To review the first clinically useful N-methyl-D-aspartate (NMDA) inhibitor for the treatment of dementia, memantine. DATA SOURCE: A MEDLINE/PUBMED search was conducted to identify pertinent studies, case reports, letters, and reviews in the English language. All articles published from 1950 to March 2003 w…

BACKGROUND: Overweight and obesity represent an increasing health problem. Both genetic and environmental factors contribute to the development of obesity. This article summarises the genetic aspects of these conditions. MATERIAL AND METHODS: A literature search was conducted using PubMed and OMIM. Both original and r…

The National Center for Biotechnology Information (NCBI) integrates data from more than 20 biological databases through a flexible search and retrieval system called Entrez. A core Entrez database, Entrez Nucleotide, includes GenBank and is tightly linked to the NCBI Taxonomy database, the Entrez Protein database, and…

The Saudi Particle Therapy Centre (SPTC) is establishing proton beam therapy (PBT) services within Kingdom of Saudi Arabia (KSA). Thus, national guidelines for the pertinent draft, and recommendations of PBT for cancer patients are utmost important. Saudi Particle Therapy Centre invited a panel of expert radiation onco…

INTRODUCTION: Artificial intelligence (AI) prognostic models in endodontics may estimate treatment outcomes, but single-pathway prediction does not provide comparative decision support for failed cases in which nonsurgical retreatment (NS-ReTx) and endodontic microsurgery (EMS) may both be considered. This scoping revi…

BACKGROUND: OLGA and OLGIM are widely used for gastric cancer risk stratification, but published studies vary in how clearly their implementation is reported. We assessed the interpretability of OLGA/OLGIM implementation reporting, focusing on reporting transparency rather than methodological correctness, study quality…

BACKGROUND: The effect and safety of atropine on delaying the progression of myopia has been extensively studied, but its optimal dose is still unclear. Therefore, the purpose of this meta-analysis is to systematically evaluate the safety and effectiveness of atropine in controlling the progression of myopia, and to ex…

Multiple sclerosis (MS) is an autoimmune and demyelinating disease of the central nervous system characterised by incoordination, sensory loss, weakness, changes in bladder capacity and bowel function, fatigue and cognitive impairment, creating a significant socioeconomic burden. The pathogenesis of MS involves both ge…

Acupuncture has emerged as an alternative therapy for Bell's palsy in both adults and children. However, the use of acupuncture is controversial. We conducted a systematic review and meta-analysis to assess the efficacy of acupuncture for Bell's palsy. We searched PubMed, Embase, and the Cochrane Central Register of Co…

INTRODUCTION: Metabolic dysfunction-associated steatotic liver disease (MASLD) is now the leading cause of chronic liver disease (CLD) globally, with increasing prevalence and risk of progression to cirrhosis, hepatocellular carcinoma, and liver-related mortality. Early detection and accurate staging are essential to g…

Pain and joint dysfunction of the upper limb following treatment for mammary carcinoma are defined as the most frequent side effects of surgery for mammary carcinoma by calculating a prevalence range in the USA that varies between 12% and 51% with regard to pain and between 1.5% and 50% for joint dysfunc…

INTRODUCTION: Perioperative hypertension is a common occurrence in anesthetic practice, potentially leading to cardiac complications resulting in unfavorable patient outcomes. Clevidipine emerges in the current drug scenario as an antihypertensive agent with advantageous properties like ultra-short half-life, titratabl…

OBJECTIVE: Several inflammatory indices have been used to assess the prognosis of ovarian cancer, with variable results. This review assessed whether the systemic immune inflammation index (SII) can predict outcomes in patients with ovarian cancer. METHODS: Embase, PubMed, CENTRAL, Web of Science, and Scopus databases…

Renal fibrosis is the central pathological process driving the progression of chronic kidney disease (CKD), representing a major global health burden. Current diagnostics, like biopsy, are invasive and lack the sensitivity for early, repeated monitoring. This creates an urgent need for noninvasive, molecularly specific…

The pervasive nature and colonial foundations of neoliberalism has significant ramifications for Indigenous health, globally. Not only does neoliberalism undermine Indigenous collectivist values by emphasising personal autonomy, but the exploitation of natural resources has unique implications for Indigenous wellbeing.…

OBJECTIVE: This systematic review supported development of a conceptual framework for user-centered process evaluations of web-based diet and exercise programs for older adults with chronic disease. METHODS: Four databases were utilized: PubMed, Embase, Business Source Premier, and ABI/Inform. Primary search terms wer…

Environmental Health Literacy (EHL) empowers individuals and communities to understand and make informed decisions about health and the environment. This study uses bibliometric indicators to map the field, identifying patterns, emerging trends, and gaps that offer opportunities for future research. We analyze 152 arti…

Maternal nutrition and gut microbiome composition are central regulators of fetal development and perinatal outcomes, modulating immune signaling, oxidative balance, and epigenetic programming. The authors searched PubMed, Scopus, the Cochrane Library, and Web of Science for full-text, peer-reviewed articles published…