Chemotherapy of advanced breast cancer. Results of a controlled trial comparing two three-drug regimens.
Chauvergne J, Berlie J, Clavel B, +6 more·European journal of cancer
Abstract not available
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Chauvergne J, Berlie J, Clavel B, +6 more·European journal of cancer
Abstract not available
Klotz J H·Biometrics
A specialization of the biased coin clinical trial randomization schemes of Pocock and Simon (1975) and Efron (1971) is proposed which gives guidelines for the coin biasing probabilities of assignment to treatment. The scheme parameterizes the often conflicting goals of random treatment assignment and allocation for st…
Napoli A, Alderuccio B, Nannetti A·La Clinica terapeutica
Abstract not available
Fawer R, Justafré J C, Berger J P, +1 more·Schweizerische medizinische Wochenschrift
Intravenous administration of glycerol under double-blind conditions (25 g twice daily for 6 days) to 26 patients with cerebral infarction localized in the territory of the middle cerebral artery temporarily improved the clinical evolution, as assessed by a scoring system, in comparison with 25 patients receiving place…
Bachmann F, Hartl W·Deutsche medizinische Wochenschrift (1946)
MK-231 (Sulindac), 200-400 mg daily, was given to 25 patients with rheumatoid arthritis. The therapeutic response was good and there were no side effects at all. The drug should be used more frequently than heretofore in the drug treatment of symptoms of rheumatoid arthritis.
Uchida K, Sakano Y, Shimizu S, +3 more·The Japanese journal of antibiotics
Abstract not available
Panell J, Charuvastra V C, Ouren J·The Medical journal of Australia
Sixty subjects participated in a double-blind study comparing methadyl acetate (80 mg) with two dosages of methadone (50 mg and 100 mg) in the maintenance of opiate addicts. The safety of all three regimens was supported and methadyl acetate was as effective as methadone in the retention of subjects.
Gyntelberg F, Jacobsen K, Martlev A, +1 more·Ugeskrift for laeger
Abstract not available
Moreno T R, Canas T R, Mestre J M·Current therapeutic research, clinical and experimental
Abstract not available
Emödi G, Rufli T·Texas reports on biology and medicine
The effect of human leukocyte interferon on varicella-zoster infections was compared in a placebo controlled study. Thirty-six patients were treated with interferon and 26 with placebo. In the interferon treated group the duration of pain was shortened, the development of crust formation was enhanced and the viral clea…
Alhava E M, Aukee S, Juuti M, +2 more·Scandinavian journal of gastroenterology
A controlled clinical study of the effect of 1000 IU of calciferol daily for 8 months was performed on patients with postgastrectomy bone loss. The treatment produced no observable increase in bone mineral density measured by photon absorption.
Paprocki J, Versiani M·Current therapeutic research, clinical and experimental
Abstract not available
Prichard B N, Boakes A J, Graham B R·Clinical science and molecular medicine. Supplement
1. A within-patient comparison showed that bethanidine, methyldopa and propranolol produced similar control of the blood pressure. 2. Unlike bethanidine, propranolol did not produce postural and exercise hypotension; methyldopa was intermediate in effect. 3. Overall side effects were of a similar incidence though there…
Liddle G W, Hollifield J W, Slaton P E, +1 more·Journal of steroid biochemistry
Abstract not available
Nilsson T, Weile F·The Journal of urology
We estimated the effect of forced diuresis in the postoperative management of prostatectomy in a prospective, controlled clinical investigation. The need for bladder irrigation in a group of patients treated with furosemide is compared to that in a group not treated with this drug. The chi-square test showed no signifi…
André C, Lambert R, Fargier M C·Biologie et gastro-enterologie
Abstract not available
Collins P, Sakalis G, Minn F L·Current therapeutic research, clinical and experimental
Abstract not available
Krogsgaard A R, Trap-Jensen J, Hartling O, +1 more·Acta medica Scandinavica. Supplementum
Abstract not available
Kirchheiner B, Fossgreen J, Tophoj E, +1 more·Rheumatology and rehabilitation
In a double-blind cross-over trial, ketoprofen was found to be as effective as indomethacin in the treatment of rheumatoid arthritis. Side-effects, particularly headache and vertigo, were less common in patients receiving ketoprofen.
Kennedy T·Acta chirurgica Belgica
Evaluation of results of different surgical treatment of duodenal ulcer requires controlled clinical trials. Some of the published trials have flaws in conception and realization: heterogeneity of material, absence of randomization, incomplete follow-up and incomplete data in results. The author presents a controlled c…