Treating asthma with anti-IgE or anti-IL5.
Lötvall J, Pullerits T·Current pharmaceutical design
In the last decades, several key mechanisms driving asthma pathophysiooogy have been discovered. These include the role of IgE in allergic disease, and the role of IL-5 in eosinophilic inflammation. In the last few years, tools to block each of these have been developed. At this time, early clinical studies with neutra…