11,352,860 papers found

The study aimed to determine how a teacher's competency at the university level related to professional commitment and job satisfaction. This systematic review intends to determine physical education teachers' competency and job satisfaction. One of the main objectives of physical education programs is to increase vari…

IMPORTANCE: Conjunctival melanoma (CM) is a highly aggressive ocular cancer for which treatment options are limited; the molecular pathogenesis is poorly understood. OBJECTIVE: To identify the molecular characteristics of CM using next-generation whole-exome sequencing (WES). DESIGN, SETTING, AND PARTICIPANTS: Whole-…

BACKGROUND: Non-suicidal self-injury (NSSI) is a significant mental health problem among adolescents. Research is needed to clarify the neurobiology of NSSI and identify candidate neurobiological targets for interventions. Based on prior research implicating heightened negative affect and amygdala hyperactivity in NSSI…

Despite the extensive research on medication-related adverse events (MRAEs) in healthcare, the assessment of the present scenario is made more difficult by the high degree of variability in study results. This study's primary goal was to create a current picture of what is currently known about the prevalence, risk fac…

Most college students sit 14 hours per week on average, excluding sedentary study time. Researchers observing workplace and elementary school settings with active workstations to combat sedentary behavior have shown enhanced cognition without distraction. Until now, incorporating active workstations in college classroo…

BACKGROUND: The family caregivers as primary caregivers play a crucial role regarding the care of cancer patients. As defined in the literature, the care burden encompasses the negative objective and subjective outcomes including psychological and physical health problems, economic and social issues, deterioration of f…

AIMS: Because many recent studies have questioned the accuracy of Doppler echocardiography (D) in determining pulmonary artery systolic pressure (PASP), we performed a detailed literature analysis attempting add clarity. METHODS AND RESULTS: Studies through 2011 comparing D and right heart catheterization (RHC) PASP,…

Analysis of tomographic volume imagery would be greatly facilitated if the objects within the volume could be presented in three-dimensionally (3D) rendered views. Such a capability has not been developed in large part because the problem of image segmentation remains unsolved. We describe a new approach that circumven…

Human body models (HBMs) play a key role in improving modern vehicle safety systems to protect broad populations. However, their geometry is commonly derived from single individuals chosen to meet global anthropometric targets, thus their internal anatomy may not fully represent the HBM's target demographic. Past studi…

Delivery of foreign opsin genes to cone photoreceptors using recombinant adeno-associated virus (rAAV) is a potential tool for studying the basic mechanisms underlying cone based vision and for treating vision disorders. We used an in vivo retinal imaging system to monitor, over time, expression of virally-delivered ge…

OBJECTIVE: This study aims to investigate the pharmacodynamic effects and underlying mechanisms of the Chinese herbal formula RuHaoDaShi (RHDS) granules against the influenza virus in experimental models. METHODS: This study aims to employ network pharmacology to identify the active components of RHDS and its potentia…

BACKGROUND: Studying illicit drug circulation and its effects on population health is complicated due to the criminalization of trade and consumption. Illicit drug markets have evolved with IT, moving digital to the "darknet." Previous research has analyzed darknet market listings and customer reviews. Research tools i…

INTRODUCTION: Sexual and gender minority (SGM) communities, including lesbian, gay, bisexual, transgender, queer, intersex, asexual, and Two-Spirit people, have historically been researched from a deficits-based approach that fails to highlight the ways communities survive and thrive in the face of adversity. This stud…

Despite the exponential growth of education in recent years, the anatomy course is taught in all medical school departments in the early years to provide a strong foundation for medical education and clinical training. Integrating technological innovations such as virtual reality programs that realistically display hum…

The dengue virus is a significant re-emerging arbovirus drawing global public health concern. Urbanization, population growth, human mobility, water access, and storage practices contribute to its transmission. This hospital-based cross-sectional study is designed to determine dengue infection and prevalence in the dis…

OBJECTIVE: Determining the concentration of prestin in human blood, cerebrospinal fluid (CSF), and perilymph (PL), and evaluating its suitability as a clinical biomarker for sensori-neural hearing loss (SNHL). STUDY DESIGN: Human blood, CSF, and PL samples were intraoperatively collected from 42 patients with tumors o…

BACKGROUND AND AIM: Previous studies have shown an association between obesity and uterine fibroids (UF). Body roundness index (BRI) is an anthropometric measure associated with obesity. However, the association with UF has not been thoroughly elucidated, and further investigation is required to explore the possible li…

Obstructive sleep apnea (OSA) is associated with circadian rhythm dysregulation plausibly through affecting clock genes. The study's purpose was to investigate the effect of one-night continuous positive airway pressure treatment (CPAP treatment) on circadian clock genes: BMAL1, CLOCK, CRY1, and PER1 at mRNA and protei…

BACKGROUND: Vaping and electronic cigarettes (e-cigarettes) have grown in popularity over the last decade with the public health desire to limit traditional smoking and nicotine delivery methods. Tobacco has been documented in the orthopedic literature to have negative effects on bone healing and to contribute to surgi…

OBJECTIVE: The purpose of this research was to ascertain how university students' eating addiction was impacted by their early experiences, picky eating, and hedonic hunger. METHODS: This descriptive cross-sectional study involved 681 university students and was carried out between April and June 2024. A sociodemograp…