44,629 papers found

INTRODUCTION: Prostate cancer is typically diagnosed following prostate biopsy. In low-risk and selected favourable intermediate-risk disease, active surveillance is the treatment strategy of choice. In these men, a confirmatory biopsy performed. We report on the rates of risk upgrading at biopsy confirmatory that may…

BACKGROUND: Ameloblastic carcinoma (AC) is a rare malignant odontogenic tumor with limited knowledge surrounding its pathogenesis, molecular pathways, clinical behavior, treatment, and prognosis. This 40-year literature scoping review aims to enhance the comprehension of this complex condition, looking closely at how A…

INTRODUCTION: Extracorporeal membrane oxygenation (ECMO) remains a mainstay for refractory respiratory failure in select pediatric patients. Clinical practice surrounding its use continues to evolve, reflecting advances in technology, management strategies, and patient selection. Ongoing research and innovation are act…

Multiple sclerosis (MS) is an autoimmune disease that involves the central nervous system. MS is prevalent among young adults and progressively destroys axons and myelin. Individuals with MS often experience complications, such as lower urinary tract dysfunction, urinary tract infections (UTIs) and sexual dysfunction.…

INTRODUCTION: Chronic cough is a persistent condition that significantly affects patients' quality of life and poses diagnostic and therapeutic challenges. Traditional anatomical diagnostic approaches often fail to address the underlying mechanisms, leading to suboptimal treatment outcomes. AREA COVERED: This review a…

OBJECTIVE: To summarize significant research contributions published in 2023 in the field of clinical decision support (CDS) systems and to select the best papers for the Decision Support section of the International Medical Informatics Association (IMIA) Yearbook 2024. METHODS: We refreshed a previous search query fo…

The social determinants of tuberculosis (TB) are well established. However, evidence indicates that genetic variants may also significantly influence an individual's susceptibility to or resistance to TB. The risk of TB is connected to polymorphisms in genes related to immunity and inflammation. While there is a growin…

To compare the outcomes of rAAV2-ND4 injection in treated versus fellow eyes with Leber's hereditary optic neuropathy (LHON). The protocol was pre-registered on PROSPERO (CRD42023441669). PubMed, Ovid MEDLINE, Cochrane CENTRAL, Google Scholar, Embase, CrossRef, OpenAlex, and Web of Science were reviewed from 1990-2023.…

Metformin is recommended as the first-line agent for the management of type 2 diabetes following lifestyle and dietary changes. The long-term use of metformin has been associated with vitamin B12 deficiency. The aim of this review is to investigate the effect of metformin on vitamin B12 levels and identify any risk fac…

OBJECTIVE: To review the current literature describing corneal changes observed with orthokeratology (ortho-k) use and to formulate preliminary recommendations for these patients seeking corneal refractive surgery. METHODS: The literature search was conducted through the PubMed, Scopus, and Ovid databases through June…

BACKGROUND: Pyridostigmine is hypothesized to improve neurogenic orthostatic hypotension (nOH) symptoms without causing or exacerbating supine hypertension. The objective of this review was to evaluate the safety and efficacy of pyridostigmine for management of nOH. METHODS: A literature search of PubMed, Embase, and…

In 15-30% of couples with infertility, no abnormalities are found after the initial diagnostic work-up. The aim of this study was to investigate the prevalence of endometriosis in patients with unexplained infertility undergoing diagnostic laparoscopy in the current era of improved imaging and assisted reproductive tec…

PURPOSE: To identify the effects of muscle energy techniques and myofascial release in patients with chronic neck pain. METHODS: To conduct a literature search and identification; PRISMA-ScR guidelines were followed. Relevant articles were searched for from the following medical and health sciences electronic database…

BACKGROUND: Recent studies investigating the effects of fish oil on shocks administered by ICDs in patients with ventricular tachycardias produced inconclusive results. This systematic review aims to evaluate the effectiveness of omega-3 polyunsaturated fatty acids in lowering the risk of life-threatening VTs among ind…

The aim of minimal intervention dentistry (MID) is to maximize the preservation of dental tissues through the use of modern and effective techniques and procedures. The central objective of MID is to increase the functional life of dental elements and, consequently, the quality of life of the population. The present st…

OBJECTIVES: Kyasanur forest disease (KFD) is a tick-borne disease in India affecting humans and two local non-human primate species. A critical knowledge gap in the scientific literature is the lack of information on how people's sociodemographic factors influence KFD occurrence. METHODS: We analyzed available data on…

The number of patients with malignant tumors is increasing in China, and venous access ports have unique advantages for chemotherapy. Currently, China's research on venous access port-mediated kinesiophobia is still in the developing stage. Using the combination of subjective words and freedom words, and based on liter…

PURPOSE: We aimed to review the literature regarding the effects of trans obturator tape surgery (TOT) on sexual functions in women with stress urinary incontinence (SUI) to reveal compact data and to reach more consistent and reliable results. METHODS: PRISMA statement was used in the current review. The databases of…

BACKGROUND AND AIM: Invasion of the central nervous system bycan occur at any stage of syphilis. In the event thatis not cleared promptly, certain individuals may experience progression to neurosyphilis, which manifests as cognitive and behavioral abnormalities, limb paralysis, and potentially fatal outcomes. Early ide…

BACKGROUND: Cannabis legalization provides an opportunity to communicate with consumers through mandated health warnings on cannabis packaging. However, research on cannabis health warnings is a nascent field. Therefore, a review is needed to synthesize cannabis health warning research and inform ongoing policy discuss…