4,953,518 papers found

Dr. Heinrich and colleagues raise concerns about our systematic review and meta-analysis (Li et al., 2022) regarding the literature screening principles, outcome data collection, and the cohort studies included in the sub-group analysis. We appreciate Dr. Heinrich and colleagues' review and suggestions on our paper (He…

The specific review question to be addressed in this review is: what is the risk of metabolic outcomes for individuals who experience rapid weight gain or catch-up growth during the first two years of life?

The objective of this scoping review is to identify and map information on how occupational therapists address their clients' perceived and experienced barriers to participation in religious occupations as part of the occupational therapy intervention.Specifically the review questions are.

The objective of this scoping review is to examine the characteristics of initial telephone consultations conducted in primary care settings and to map the existing evidence on the components, skills and training recommended for initial telephone consultations in current primary care.This scoping review will be guided…

The objective of the review is to synthesize evidence regarding the experiences of unpaid caregivers of community-dwelling adults with dementia. Specifically, the review question is: What are the experiences and perceptions of unpaid caregivers providing care for community-dwelling adults with dementia?

The value of a systematic review or meta-analysis depends upon the care with which it is designed and conducted. A major factor in this is the literature search that identifies the articles to be reviewed. Careful selection of bibliographic databases and the use of well-designed search strategies based on the controlle…

Candidemia in the pediatric burn population poses a management dilemma due to the paucity of good clinical data to guide treatment decisions. Whilst candidemia is less common than bacteremia in pediatric burns patients, it is associated with significant morbidity and mortality. We report a case of candidemia in an infa…

The American College of Chest Physicians comprehensive review of continuing medical education is an ambitious attempt to summarize a vast and heterogeneous literature. Nevertheless, there appear to be some consistencies; multiple media and instructional methods appear to be consistently better than single approaches, a…

Spontaneous regression of intracranial arteriovenous malformations (AVMs) is a rare phenomenon. Such an event is more likely to occur with small AVMs that present with intracranial hemorrhage, which are fed by a unique artery and drained through a single vein. The factors responsible for AVMs regression remain unclear.…

Bronchiolitis obliterans and organizing pneumonia (BOOP) is a syndrome that has been associated with a variety of underlying disorders, including infection, collagen vascular diseases and toxic fume inhalation. Rarely, however, BOOP has been associated with radiation- or chemotherapy-induced pulmonary toxicity. Over th…

BACKGROUND: The impact of poor nutritional health on maternal and infant morbidity and mortality remains high in low- and middle-income countries (LMICs), exacerbated by climate change-linked disasters. Maternal nutritional health, as a modifiable factor, is influenced by various social, political, economic and environ…

BACKGROUND: Epidermolysis bullosa (EB) is a group of rare congenital inherited skin diseases. Evaluation of health-related quality of life (HRQoL) is key to understanding the psychosocial and emotional impact on patients and their relatives or carers. The BUR-EB project aims at ascertaining the socio-economic burden of…

BACKGROUND: Globally, agricultural production systems consume two-thirds of all antimicrobials. These systems are used to raise animals that produce products for consumption, such as meat, eggs, milk, and wool. The World Bank estimates that by 2030, AMR will reduce global livestock production by up to 7.5%, resulting i…

INTRODUCTION: Dengue fever is a major global public health challenge caused by the Arbovirus and transmitted by Aedes mosquitoes. The increasing incidence of dengue, particularly in the Southeast Asia (SEA) region, including Malaysia, highlights the urgent need for a comprehensive understanding of dengue molecular epid…

BACKGROUND: Infection is a common problem and a major cause of morbidity and mortality for patients in intensive care units (ICUs). According to published meta-analyses, oral care has been found to reduce the risk of nosocomial pneumonia, and has been recommended to improve the oral environment for patients in ICUs. Ho…

BACKGROUND: Corneal transplantation is the most frequently performed transplantation in the UK. Despite this, the therapeutic value of matching human leukocyte antigen (HLA) subtypes for transplanted corneas remains controversial. Ocular immune privilege was originally deemed to render matching unnecessary; however, mo…

BACKGROUND: Antimicrobial resistance (AMR) is an escalating global health issue with complex and dynamic interdependencies, high uncertainty and decision stakes, multiple drivers and stakeholders with diverse values and interests, and various aspects and outcomes. Addressing and combating this critical global challenge…

BACKGROUND: Studies on several preclinical models of type 2 diabetes mellitus have been conducted to establish the hypoglycemic activity of Momordica charantia L. Concerned with appropriateness of these models, we designed a systematic review to establish the efficacy and safety of M. charantia L. in preclinical models…

INTRODUCTION: Sedentary behaviour is defined as any waking behaviour characterised by low energy expenditure ≤1.5 metabolic equivalents while in a sitting, lying or reclining posture. The expanding evidence base suggests that sedentary behaviour may have a detrimental effect on health, well-being and is associat…