11,527,996 papers found

Loudness dependence of auditory evoked potentials (LDAEP) has been proposed as a biological marker of central serotonergic activity related to suicides. This study's objective was to analyze the difference in LDAEP between depressed patients with suicide attempts (SA) and suicidal ideation (SI). It included 130 partici…

INTRODUCTION: Sulforaphane (SFN) is an isothiocyanate derived from glucoraphanin (GRA), which is found in great amounts especially in broccoli. Its consumption has been reported to be associated with a lower risk of myocardial infarction and cancer development. Additionally, its effects have been studied in neurodegene…

BACKGROUND: The global prevalence of Diabetes Mellitus is steadily increasing, leading to a larger diabetic population undergoing root canal treatment (RCT). However, clinical studies assessing anesthetic success in diabetic patients are lacking. In diabetic patients, local anesthetic success may be affected owing to n…

BACKGROUND: Hispanic/Latino (H/L) heritage civilians out-number all other non-White ethnic groups in the United States. When studied as one group, H/L diversity is ignored, including rates of drug misuse. This study's aim was to examine H/L diversity regarding drug dependence by disaggregating how the burdens of active…

BACKGROUND: Designing questionnaires is a key point of epidemiological studies assessing human exposure to chemicals. The lack of validated questionnaires can lead to the use of previously developed and sub-optimally adapted questionnaires, which may result in information biases that affect the study's validity. On thi…

OBJECTIVES: To assess international comparability of general cost of illness (COI) studies and to examine the extent to which COI estimates differ and why. METHODS: Five general COI studies were examined. COI estimates were classified by health provider using the system of health accounts (SHA). Provider groups fully…

BACKGROUND: The World Health Organization (WHO) developed the model list of essential in vitro diagnostics (EDL) to guide countries to develop and update point-of-care (POC) per their disease priorities. The EDL includes POC diagnostic tests for use in health facilities without laboratories; however, their implementati…

With the continued increase in the use of Bayesian methods in drug development, there is a need for statisticians to have tools to develop robust and defensible informative prior distributions. Whilst relevant empirical data should, where possible, provide the basis for such priors, it is often the case that limitation…

BACKGROUND:  Despite government initiatives to ensure the delivery of safe and high-quality care in health establishments, most health establishments in the City of Tshwane Metropolitan Municipality, South Africa were non-compliant with the National Core Standards. This study explored the experiences of quality as…

BACKGROUND: To describe the BV anatomy in detail, to compare previous BV descriptions and illustrations to the current study's findings and photograms, to show the BV topographic relation of the BV to the urethral meatus, to document the BV anatomy using photograms. METHODS: Ten fresh human female adult cadavers were…

In the early 1990s, a combination of 5-fluorouracil (5-FU) and cisplatin was widely adopted to treat advanced gastric cancer; however, no survival advantage over single-agent 5-FU was confirmed by the results of randomized trials conducted over a long period. Recently developed agents such as irinotecan, taxanes (docet…

There are several population-based studies of aging, memory, and dementia being conducted worldwide. Of these, the Cache County Study on Memory, Health and Aging is noteworthy for its large number of "oldest-old" members. This study, which has been following an initial cohort of 5,092 seniors since 1995, has reported a…

Examined differences between asserters and nonasserters and between the sexes on anger expression. Thirty-seven male and 53 female college students were administered the College Self-Expression Scale, the Buss Durkee Hostility Inventory, and the Anger Self-Report. As hypothesized, asserters and males expressed more ang…

In this consensus report by a diverse group of academics who conduct and/or are concerned about social and behavioral genomics (SBG) research, the authors recount the often-ugly history of scientific attempts to understand the genetic contributions to human behaviors and social outcomes. They then describe what the cur…

OBJECTIVES: The knowledge about the molecular pathway of traumatic pain relief is less documented. This systematic review study aimed to identify the genes and molecular pathways associated with various traumatic pains. METHODS: The online databases such as EMBASE, MEDLINE, PubMed, Cochrane Library, International Clin…

Health information technologies (HITs) are widely employed in healthcare and are supposed to improve quality of care and patient safety. However, so far, their implementation has shown mixed results, which might be explainable by understudied psychological factors of human-HIT interaction. Therefore, the present study…

Accelerometer-based systems are often used to quantify human movement. This study's aim was to assess the reliability and validity of the Myotest® accelerometer-based system for measuring running stride kinematics. Twenty habitual runners ran two 60 m trials at 12, 15, 18 and 21 km·h(-1). Contact ti…

Despite the ubiquity of membrane occupation recognition nexus (MORN) motifs across diverse species in both eukaryotic and prokaryotic organisms, these protein domains remain poorly characterized. Their significance is underscored in the context of the Alsin protein, implicated in the debilitating condition known as inf…

Medical staff is vital for helping society through a health crisis, human-made or natural disaster, and pandemic. This study aims to investigate the medical staff's work-related burnout during Covid-19 and their willingness to work when they are most needed. The cross-sectional design was used, and an online survey was…

Talc may lodge in human tissues through various routes, and has been associated with the development of ovarian carcinoma in case control epidemiologic studies. Talc is detected in tissues with scanning electron microscopy and energy dispersive X-ray analysis (SEM/EDS), with expected magnesium (Mg) and silicon (Si) pea…