42,210 papers found

IMPORTANCE: Publishing study protocols might reduce research waste because of unclear methods or incomplete reporting; on the other hand, there might be few additional benefits of publishing protocols for registered trials that are never completed or published. No study has investigated the proportion of published prot…

The aim of this review is to analyze the available literature regarding the neuropsychiatric (NP) disturbances associated with corticosteroid (CS) therapy; to determine the nature, severity, and frequency of these NP symptoms; and to identify the various risk factors involved in the development of CS-induced NP disturb…

BACKGROUND/AIM: The proportion of patients with liver metastases in patients with appendiceal versus colorectal adenocarcinomas was 3.1 percent and 24 percent, respectively, in our peritonectomy centre. From our internal analyses, carcinoembryonic antigen (CEA) was potentially involved. A hypothesis was proposed regard…

OBJECTIVE: To understand and highlight the current issues, emerging trends, and regulations of kratom in the United States. DATA SOURCES: PubMed and PubMed Central of the National Library of Medicine, MEDLINE, PsycINFO, and ClinicalTrials.gov databases were utilized. STUDY SELECTION: Studies published between January…

BACKGROUND: Studies comparing data between the high-power short-duration radiofrequency (HPSR) and low power longer duration therapy were limited and inconsistent. Therefore, we conduct a high-quality systematic review and meta-analysis to assess the efficacy and safety of HPSR on outcomes for patients with atrial fibr…

OBJECTIVE: To synthesize evidence on the effectiveness of multidisciplinary self-management interventions for glycaemic control in people with type 1 diabetes. INTRODUCTION: Type 1 diabetes is a chronic autoimmune disease. Self-management education led by a multidisciplinary team facilitates those with diabetes to acq…

BACKGROUND: This study will evaluate the effectiveness of different acupuncture courses for functional constipation (FC) through network meta-analysis. METHODS: Eight database (PubMed, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials (Central), China National Knowledge Infrastructure (CNKI), Chin…

INTRODUCTION: Brain stroke is the second most common cause of death and major cause of disability in adults, representing a huge burden on patients and their families. Hydrokinesitherapy, a type of physical rehabilitation, may be beneficial to post-stroke recovery. We will systematically assess the clinical effectivene…

INTRODUCTION: The most common cell type in the central nervous system (CNS), astrocytes, is also the cell type most commonly associated with the brain cancer called astrocytoma. Advances in genetic/molecular techniques led to the 2021 CNS tumor reclassifications. In this review, we will simplify the somewhat complex 20…

Abdominoplasty is a widely utilized cosmetic surgery procedure. Despite its popularity, seroma formation remains a prevalent complication. Seroma can lead to extended recovery time, increased medical appointments, and the potential for infection or the need for additional surgical revision. Preserving Scarpa's fascia m…

PURPOSE: Tissue synthesis is extremely important for the attenuation of postoperative discomforts, as it keeps the tissues coapted, accelerates the healing process, and reduces the bleeding period of the surgical wound. Thus, this study aimed to systematically review the results of clinical trials that compared the use…

INTRODUCTION: Recent studies have shown that musical practice and training are effective and have the potential to assist in the acquisition and improvement of auditory skills. OBJECTIVE: To verify the scientific evidence on the implications of musical practice in central auditory processing. METHODS: A systematic re…

BACKGROUND: Around twenty million new cases and ten million of deaths were attributed to cancer in 2018. Physical exercise, as main component of prehabilitation programs, has been associated with clinical improvements in aerobic capacity, muscular strength, gait speed, and fewer postoperative complications. This system…

BACKGROUND: There is a wide variety of dressings currently available for the treatment of diabetic foot ulcers (DFUs). Because of a lack of evidence from head-to-head randomized controlled trials (RCTs), the relative effects of these dressings in DFU patients remain unclear. This study compared the efficacy of nine dre…

AIM: This study evaluated the efficacy of replacing single missing teeth in the posterior quadrants of the maxilla and/or mandible with an implant-supported dental prosthesis. MATERIAL AND METHODS: Three scientific literature databases - Medline (Pubmed), Ovid Medline and Cochrane Central Register of Controlled Trials…

Pediatric dural arteriovenous shunts (dAVSs) are a rare form of vascular disease: Fewer than 100 cases are reported in PubMed and the understanding of pediatric dAVS is limited. For this study, we searched in PubMed, reviewed and summarized the literature related to pediatric dAVSs. Our review revealed that pediatric d…

PURPOSE: Immediate implantation has become one of the therapeutic options for replacement of a hopeless tooth. In the case of a tooth with a periapical lesion, this approach remains controversial. The aims of this article were to systematically review the evidence on immediate implants in sites with periapical lesions…

BACKGROUND: This study aims to identify whether reinforcing the staple line during laparoscopic sleeve gastrectomy (LSG) has advantages. METHODS: We searched MEDLINE (PubMed; till August 2011), EMBASE (till August 2011), and the Cochrane Central Register of Controlled Trials (Central) in the Cochrane Library (till Aug…

BACKGROUND  Several published studies have evaluated the efficacy of tacrolimus in the management of Crohn's disease with variable conclusions. AIM  To review systematically the evidence examining the efficacy and safety of tacrolimus in treating Crohn's disease. METHODS  The Cochrane Central Regis…

IMPORTANCE OF THE FIELD: Primary central nervous system lymphomas (PCNSL) are rare but potentially curable tumours. The overall outcome for PCNSL patients is unsatisfactory and several therapeutic questions remain open. Modest progress in outcome reflects difficulties in conducting randomized trials and scarce molecula…