11,352,426 papers found

Strip perforation repair is one of the most challenging treatments in endodontics. Marginal adaptation is a crucial factor in evaluating the sealing ability of materials. This study aimed to microscopically examine the marginal adaptation of bioceramic-based sealers, MTA-Angelus, and Cold Ceramic in repairing strip per…

BACKGROUND: The incidence of breast cancer is escalating into millions of cases annually all over the world with hundreds of thousands of deaths recorded each year. It has been well established that breast cancer is caused by both genetic and non-genetic factors. However, there is a paucity of information on breast can…

Di-(2-ethylhexyl) phthalate (DEHP), a phthalate plasticizer, is widely spread in the environment, presenting hazards to human health and food safety. Hence, this study examined the probable preventive role of coenzyme10 (CQ10) (10 mg/kg.b.wt) against DEHP (500 mg/kg.wt) - induced neurotoxic and neurobehaviora…

N'-nitrosonornicotine (NNN) induces tumors in the rat nasal cavity and esophagus and is believed to be a causative agent for esophageal cancer in tobacco users. To exert its carcinogenic potential, NNN must be metabolically activated by alpha-hydroxylation at either the 2'- or 5'-carbon. We previously reported that the…

This study's purpose is to characterize the performance of a prototype functional near-infrared spectroscopy (fNIRS) headband meant to enable quick and easy measurements from the sensorimotor cortices. The fact that fNIRS is well-suited to ergonomic designs (i.e., their ability to be made wireless, their relative robus…

BACKGROUND: Hyperglycemia is a common adverse event associated with parenteral nutrition (PN); however, there is no consensus on optimal glucose monitoring. Unnecessary point-of-care (POC) blood glucose (BG) testing can result in additional healthcare cost and discomfort to the patient. This study's aim was to determin…

Epigenome association studies that test a large number of methylation sites suffer from stringent multiple-testing corrections. This study's goals were to investigate region-based associations between DNA methylation sites and lipid-level changes in response to the treatment with fenofibrate in the GAW20 data and to in…

Colorectal cancer (CRC) remains a major global health challenge, with high recurrence and mortality despite advances in surgery, chemotherapy, and immunotherapy. The study by Heidentifies a novel mechanism by which peroxiredoxin 1 (Prdx1) inhibits CRC progression through induction of pyroptosis, a pro-inflammatory form…

This study developed a highly sensitive and efficient method for the detection of brucellosis by introducing a one-tube nested quantitative real-time PCR (qPCR) approach, representing a remarkable advance in the field. The method demonstrated an impressive analytical sensitivity of 100 fg/μL, surpassing conventio…

The circular RNAs (circRNAs) involved in competitive endogenous RNA (ceRNA) mechanism are critical modulators affecting pathogenesis of thyroid carcinoma (TC). The study's goal was to investigate the effects of circ 0003747 on the biological progression of papillary thyroid cancer (PTC). Normal thyroid cells Nthy-ori3-…

BACKGROUND: Burn is one of the most brutal harms to the human body and mind and its wide-ranging complications have many adverse effects on the patients' quality of life. The present study was conducted to investigate the effect of rehabilitation education through social media on burn patients' quality of life. METHOD…

As the living standards of urban residents in China continue to improve, the number of motor vehicle trips is increasing, thus aggravating air pollution. Such pollution causes great harm to human health and the global environment. Using a system dynamics approach, this study analyzed the effect of implementation mode o…

Femicide is the intentional killing of a woman or girl on account of her gender. The term allows differentiating crimes of gender violence from murders of women in other circumstances. The aim of this study is to characterize femicides, sometimes called feminicides, that occurred in 2015 in Campinas, São Paulo Sta…

Microwave-induced thermoacoustic imaging (MITAI) is an imaging technique with great potential for detecting breast cancer at early stages. Thermoacoustic imaging (TAI) combines the advantages of both microwave and ultrasound imaging techniques. In the current study, a three-dimensional novel numerical simulation of TAI…

Adolescent sexual health is often reflected through a problem-oriented lens. This serves to reinforce prevailing sexual scripts and cultural images of disenfranchised youth. Very little is known about the support young people in foster care, particularly youth of color, need to stay sexually healthy and safe. This arti…

BACKGROUND AND AIMS: Carbohydrate sulfotransferase 15 (CHST15) promotes tumor growth and invasion and is considered to be an emergent therapeutic target for pancreatic cancer. The aim of this study was to evaluate the safety and efficacy of EUS-guided fine-needle injection (EUS-FNI) of STNM01, the double-stranded…

Variations in people's vulnerability to stressful life events may rise from a predated neural sensitivity as well as from differential neural modifications in response to the event. Because the occurrence of a stressful life event cannot be foreseen, characterizing the temporal trajectory of its neural manifestations i…

OBJECTIVE: This article outlines the development and validation of the Informal Supporter Readiness Inventory (ISRI), based on the model developed by the present authors in (Davies, 2023). This scale assesses the readiness of informal supporters to intervene or provide support in situations of intimate partner violence…

Experience with an object's photograph changes 9-month-olds' preference for the referent object, confirming they can represent objects from pictures. However, picture-based representations appear weaker than object-based representations. The current study's first objective was to investigate age differences in object r…

BACKGROUND: This research explores the repercussions of the COVID-19 emergency on women's enablement worldwide, scrutinizing data spanning 93 nations between 2019 and 2020. METHODS: The investigation employs sectional data examination of various metrics pertinent to women's empowerment, encompassing the ratio of emplo…