96,746 papers found

BACKGROUND: The LNG-IUS has increasingly been used for contraception, treatment of menorrhagia and endometrial protection during hormone replacement therapy since mid-1990s. Thus, many women use the LNG-IUS consecutively. However, published data on the bleeding pattern regarding consecutive use of the LNG-IUS is scarce…

Purpose of this study was to determine the rate of contamination, defined as lung cancer screening in the control arm, of the Dutch-Belgian randomized lung cancer screening trial (NELSON) as contamination adversely affects the power of a trial. The NELSON cohort includes 15,822 high-risk current and former smokers, age…

BACKGROUND: Oral fluid (OF) is an exciting alternative matrix for monitoring drugs of abuse in workplace, clinical toxicology, criminal justice, and driving under the influence of drugs (DUID) programs. During the last 5 years, scientific and technological advances in OF collection, point-of-collection testing devices,…

BACKGROUND: Previous studies have shown an association between diabetes mellitus (DM) and urinary incontinence (UI) in women, especially severe UI. The purpose of this study was to investigate whether diabetes related variables could explain this association. METHODS: The study is part of the EPINCONT study, which is…

PURPOSE: Natural orifice transluminal endoscopic surgery (NOTES) is a novel technique that aims at reducing or abolishing skin incisions and potentially also postoperative pain. The purpose of this study was to analyse operative and long-term results of a series of hybrid transvaginal cholecystectomy. MATERIALS AND ME…

Recent studies have shown that the detrimental effects of sports concussions on cognitive and motor function may persist up to a few years post-injury. The present study sought to investigate the effects of having sustained a sports concussion more than 30 years prior to testing on cognitive and motor functions. Ninete…

BACKGROUND: Although the ideal treatment of thumb basal joint osteoarthritis is debated, most surgeons advocate trapeziectomy with ligament reconstruction tendon interposition arthroplasty. However, harvesting and weaving autologous tendon creates scarring, alters wrist kinetics, may prolong recovery, and is time consu…

OBJECTIVE: We sought to examine the frequency and the specific problems encountered in accessing Internet references in two leading medical journals during the last 3 years. METHODS: Two investigators independently reviewed all publications in the issues of the New England Journal of Medicine and The Lancet during Oct…

BACKGROUND: Although patients with pectus carinatum (PC) often experience moderate to severe symptoms, there are sparse published data about the indications for correction, the newer techniques of surgical repair, and the results. This study reviews clinical experience with new, less extensive, open operative technique…

INTRODUCTION: Secondary adaptive bone changes and joint distorsions in clubfoot may present a barrier to adequate correction of the deformity. The purpose of our study is to show how the lateral excision of the calcaneus distal part as described by Lichtblau, in combination with an appropriate medial release allows bet…

The 5-year survival rate for malignant melanoma has increased 40% over the last 50 years. During this same time period, the treatment for the disease has not changed significantly, and consists of wide excision of the primary tumour and perhaps regional node dissection. The purpose of this study was to investigate the…

Thomas is a 13-year-old boy with autism spectrum disorder, attention deficit hyperactivity disorder (ADHD), generalized anxiety disorder, separation anxiety disorder, and major depressive disorder who presented for a follow-up to his developmental and behavioral pediatrician (DBP). His mother describes an increase in s…

OBJECTIVES: In the last 20 years, with the use of computed tomography (CT) angiography, the number of patients diagnosed with pulmonary thromboembolism (PTE) has increased. At the same time, data show that pulmonary embolism mortality has also reduced in this duration. MATERIAL AND METHODS: In this study, we analyzed…

The rate of supernovae in our local Galactic neighbourhood within a distance of about 100 parsecs from Earth is estimated to be one every 2-4 million years, based on the total rate in the Milky Way (2.0 ± 0.7 per century). Recent massive-star and supernova activity in Earth's vicinity may be traced b…

The aim of the study was to evaluate the reliability of methods used for forensic dental age estimation. We analysed all cases over the last 21 years (1984-2004) of unidentified bodies that were examined for identification purposes (including age assessment), and of which secure identification was subsequently achieved…

OBJECTIVE: To determine the rate of rejection for prosthetic use in children and to investigate reasons for this rejection. DESIGN: Cross-sectional study of a cohort of children. SETTING: Rehabilitation centre, St Maartenskliniek, Nijmegen, The Netherlands. SUBJECTS: Thirty-two children (0-18 years) with a unilatera…

We performed a retrospective chart and radiograph review of 10 patients with a history of poliomyelitis involving a limb that subsequently underwent primary total knee arthroplasty between 2000 and 2008. One posterior stabilized (PS), two condylar constrained (CCK), and seven rotating hinge (RHK) prostheses belonging t…

AIMS AND BACKGROUND: To update trends in smoking prevalence in Italy to 2003, with specific focus on the young. METHODS: A population-based, face-to-face survey conducted in February-April 2003 on 3,535 individuals aged 15 or over, representative of the whole Italian adult population, plus an over sampling of 426 subj…

PURPOSE: Amputation of the penis or emasculation in children is rarely reported in the medical literature. This study involves 7 children with these injuries admitted to the University Hospital San Vicente de Paul, Medellin, Colombia, from 1960 to 1995. A new surgical technique is described for penile reconstruction th…

Liver transplantation (LT) has emerged as the best therapeutic modality for end-stage liver disease in pediatric autoimmune liver disease (AILD). We aimed to describe our experience of pediatric living donor liver transplantation for AILD from India over a period of 10 years. We did a retrospective analysis of 244…