96,746 papers found

In recent years, substantial progress has been made in understanding the molecular and cell biology of the human parasite, an important pathogen with significant global impact. This review outlines some recent advances in thefield in the last five years, focusing on areas that have not recently been discussed in detail…

The history of hepatic encephalopathy (HE) is briefly reviewed since the beginning of western medicine by Hippocrates. For about 2000 years the main evidence was the mere association between jaundice, fever and delirium. A clear link between delirium and cirrhosis was proven in the 17th century by Morgagni. In subseque…

Automated processing of mammograms has been studied for several years. Until the last few years much of the efforts have produced marginal results due to the limitations of inexpensive hardware. Even with the advanced hardware no one has yet taken an entire mammogram and determined whether it is normal or abnormal. We…

The story of fatty acid ethyl (FAEE) encompasses nearly 40 years of research. For more than half of this time, the investigation was limited to documenting the presence of ethyl ester synthesis in different cells and tissues. In the last three years, increasing evidence has emerged that FAEE contribute to ethanol-induc…

We report our experience with 8 women with perineal endometriosis managed in a period of 20 years. All were multiparae women presenting with cyclical perineal painful masses related to menstrual periods. Symptomatology started 6 months to 16 years after last delivery. Three patients had partial involvement of the anal…

Diagnosis and treatment of primary hyperparathyroidism has changed substantially during recent years. Routine serum calcium measurements and development of specific as well as sensitive PTH assays made primary hyperparathyroidism the most prevalent diagnosis of hypercalcaemia in the normal population. With increasing n…

Twenty cases of hepatic granulomas seen in the Department of Medicine over the period of 8 years from 1981-1988 were reviewed. Prolonged fever and jaundice were the commoner presentations. While the aetiology was varied, patients with tuberculosis and idiopathic causes formed the major groups. There were also 2 rare ca…

The treatment of osseous defects is widely established in the elderly. The number of positive reports on the successful application of bovine as well as coralline hydroxyapatite ceramics has continuously increased during the last few years. In trauma surgery hydroxyapatite ceramics are most commonly applied in metaphys…

Liver transplantation (LT) has emerged as the best therapeutic modality for end-stage liver disease in pediatric autoimmune liver disease (AILD). We aimed to describe our experience of pediatric living donor liver transplantation for AILD from India over a period of 10 years. We did a retrospective analysis of 244…

OBJECTIVES: To vertically analyze the trend of surgical approaches, demographics, surgical morbidity, and long-term survival outcomes of early-stage cervical cancer over the past 11 years and to determine whether there have been any significant changes. METHODS: A total of 851 patients with consecutive International F…

IMPORTANCE: Thirty-five years ago, the Heckler Report described health disparities among minority populations in the US. Since then, policies have been implemented to address these disparities. However, a recent evaluation of progress towards improving the health and health equity among US adults is lacking. OBJECTIVE…

BACKGROUND: The ideal treatment of osteochondral lesions of the talus (OLT) is debatable. The TruFit plug has been investigated as a potential treatment method for osteochondral defects. This is a biphasic scaffold designed to stimulate cartilage and subchondral bone formation. The purpose of this retrospective study w…

OBJECTIVE: To explore the effectiveness of stage I anterior approach debridement and autologous iliac crest graft with single self-locked titanium plate internal fixation for the treatment of lumbosacral tuberculosis. METHODS: Seven cases of lumbosacral tuberculosis were treated by stage I anterior approach debridemen…

OBJECTIVES: Asthma and allergic rhinitis are diseases which require special attention in childhood. Risk factors for these diseases are manifold and include environmental factors. Previous studies have shown associations between indoor mould and respiratory diseases in children. Besides indoor mould, organic waste stor…

BACKGROUND: Health-related quality of life (HRQL) is deemed to be a meaningful endpoint when evaluating therapy and prevention interventions. For comparison purposes not only patient data but also representative population samples can serve as reference data. We aim to describe differences between the Luebeck populatio…

Synthetic polymer chemistry has undergone two major developments in the last two decades. About 20 years ago, reversible-deactivation radical polymerization processes started to give access to a wide range of polymeric architectures made from an almost infinite reservoir of functional building blocks. A few years later…

OBJECTIVE: To describe the demographic and clinical profiles of a cohort of environmentally representative severe traumatic brain injury (TBI) cases collected for the past 25 years and to analyse the changes that occurred by dividing the analysis period into 3 equal time periods. MATERIAL AND METHODS: This was an obse…

Tapered femoral components were designed to provide a cementless alternative in patients with narrow femoral canals. Major concerns with this stem include perioperative fracture and thigh pain. To ascertain the frequency of these concerns, we retrospectively reviewed 100 consecutive hips in 97 patients who underwent to…

A review of the Princess Margaret Hospital experience over the last 20 years in treating clinically staged patients with stage I and II Hodgkin's disease was performed to analyse the impact of patient selection and extended field radiation on relapse and survival. Of the 878 patients with stage I and II Hodgkin's disea…

UNLABELLED: Pes cavus is a complex foot deformity in which surgical correction remains challenging. We treated lesser-toe clawing in 11 feet of 8 patients (5 women, 1 bilateral; 3 men, 2 bilateral) with a modified Jones procedure and assessed long-term functional outcomes. We reviewed case notes and completed the Brist…