42,210 papers found

Diabetic foot ulcers (DFU) represent a severe chronic complication of diabetes with increasing global prevalence. Approximately 75% of lower limb amputations are attributable to diabetic foot disease, and the 5-year mortality rate following amputation ranges from 53% to 100%. The pathogenesis of DFU involves multiple i…

High myopia is increasingly prevalent and complicates glaucoma diagnosis. Axial elongation remodels the optic nerve head (ONH) and parapapillary tissues, producing structural and functional changes that mimic glaucoma-termed myopic optic neuropathy (MON). We reviewed current concepts on the MON-glaucomatous optic neuro…

Osteoarthritis (OA), particularly of the knee, represents a leading cause of chronic pain and functional limitation worldwide. Although pharmacologic therapy remains central to symptom control, real-world treatment effectiveness is frequently compromised by suboptimal medication adherence. To synthesize contemporary ev…

BACKGROUND: Altruism has historically shaped the ethos of nursing. However, the COVID-19 pandemic reignited nurses' profound commitment to patient care, often at significant personal risk to own health and safety. This renewed dedication has prompted interest in whether altruism remains a vital component of nursing pra…

INTRODUCTION: Antibody-drug conjugates (ADCs) are an expanding class of targeted cancer therapies that combine monoclonal antibody specificity with potent cytotoxic agents, offering improved precision and efficacy across multiple malignancies. As their clinical use increases, there is a growing need to address the crit…

INTRODUCTION: Gestational diabetes mellitus (GDM) is a common pregnancy complication associated with reduced breastfeeding rates. Breastfeeding interventions are essential in supporting women with GDM. This review evaluated the effectiveness of interventions that support breastfeeding among women with GDM. METHODS: A…

As a gastrointestinal hormone, gastrin stimulates gastric acid secretion and intestinal mucosal nutrition. Evidence links it closely to coronary heart disease, ischemia‒reperfusion injury and hypertension. The relevant literature was systematically retrieved from PubMed, Web of Science, China National Knowledge…

PURPOSE: The aim of this study is to review the literature and reflect on the importance of sensory perceptions-colors, sounds, odors, taste, and kinetics (tactile and postural)-alongside team behavior and safety culture in the operating room. METHODS: MEDLINE search via PubMed up to March 2025, using both free terms…

: High Mobility Group Box 1 is a mediator in inflammation, acting as a damage-associated molecular pattern molecule in various diseases. This review examines its role in nasal inflammatory disorders, such as chronic rhinosinusitis and allergic rhinitis.: A comprehensive review of recent literature was conducted using a…

INTRODUCTION: Transcatheter aortic valve replacement (TAVR) is increasingly performed nowadays, bleeding and vascular complications are not uncommon. Current recommendations for the use of protamine in the post-TAVR setting remain uncertain. This study aimed to evaluate the efficacy and safety of protamine in this sett…

<i>Pseudolachnostylis maprouneifolia</i> Pax is a well-known and widely used medicinal plant in Central and Southern Africa. The current study was aimed at documenting the medicinal uses, phytochemical and pharmacological properties of <i>P. maprouneifolia</i>. The literature search on existing…

Transgender and gender-diverse (TGD) people are disproportionately affected by interpersonal violence and face barriers to accessing post-violence health services globally. Post-violence care guidelines are broadly applicable, but specific considerations for TGD individuals have not been synthesised. In this systematic…

PURPOSE: Ophthalmia nodosa is an inflammatory ocular condition caused by the penetration of arthropod hairs (setae) into the eye. This review aims to systematize current knowledge on the condition, identify knowledge gaps, and propose an updated classification. METHODS: A systematic literature review was conducted in…

BACKGROUND: Breast and nipple-areolar complex (NAC) sensation after breast reconstruction impacts postoperative quality of life. Autologous breast reconstruction (ABR) and implant-based breast reconstruction (IBBR) are standard techniques. Neurotization has shown promise in improving sensory outcomes. METHODS: A compu…

BACKGROUND: The world has experienced numerous natural and man-made disasters throughout history. Due to these unforeseen circumstances, children and adolescents have reported significant psychopathologies in response to traumatic experiences. We aimed to investigate the surge of internalizing and externalizing psychop…

PURPOSE: Tear film instability is one of the principal pathomechanisms of dry eye disease (DED), arising from disrupted tear homeostasis, reduced tear volume, or lipid layer alterations. The lipid layer, secreted by the meibomian glands, can be imaged qualitatively and quantitatively. This review summarizes different l…

Retrieval analysis in total knee arthroplasty (TKA) has been little studied in the literature. A narrative review of the literature to understand the current importance of retrieval analysis in TKA has been conducted. On August 27, 2024, a literature search was performed in PubMed using "TKA retrieval analysis" as keyw…

BACKGROUND: Accurate decision-making in triage largely determines the amount of time required for a patient to be evaluated and treated while in the emergency department. Nursing staff worldwide have similar learning characteristics with similar working hours and common goals, despite the fact that different triage sca…

The objective of this systematic literature review was to investigate the effect of Coca-Cola on the properties and, more generally, on the integrity of direct dental filling materials. In addition, it aimed to highlight the importance of dietary behaviour in dentistry and, in this context, to identify tangible strateg…

OBJECTIVE: Religiosity is a complex construct comprised observance, intrinsic beliefs, meditative practice, and communal elements. Religiosity has been associated with reduced mortality and improved overall health, but understanding the underlying biological associations is evolving. As increased telomere length has be…