11,527,449 papers found

CONTEXT: Osteoarthritis (OA) is the most common form of arthritis, affecting an estimated 302-million people worldwide, and it's a leading cause of disability among older adults. Current treatments for OA are largely unsatisfactory. Ozone is an inexpensive, accessible, and easily applicable treatment for OA. OBJECTIVE…

OBJECTIVES: Psychological morbidities after injury [eg, posttraumatic stress disorder (PTSD) and depression] are increasingly recognized as a significant determinant of overall outcome. Traumatic brain injury (TBI) negatively impacts outcomes of patients with orthopaedic injury, but the association of concurrent TBI, o…

AIMS: The aim of this study was to evaluate the effect of valve surgery (VS) in infective endocarditis (IE) on 5-year mortality and to evaluate whether conflicting results reported by previous studies could be due to differences in their methodological approaches. METHODS AND RESULTS: Four hundred and forty-nine patie…

The comparison of the complement inhibitor s-protein, isolated from human plasma, with vitronectin, a serum spreading factor, revealed a high degree of similarity of both proteins with respect to molecular weight, band pattern in polyacrylamide gels in the presence of sodium dodecyl sulfate and amino acid composition.…

Understanding the role of people in occupational accidents is very difficult. It is always assumed that people perform the behaviour that feels right to them. This study's main topic is the relationship between values, which form the basis of human behaviour, and safety motivation, fatalistic tendencies, risk perceptio…

Significant challenges confronting China include reducing carbon emissions, dealing with the resulting problems, and meeting various requirements for long-term economic growth. As a result, the shift in industrial structure best reflects how human society utilizes resources and impacts the environment. To meet China's…

Recurrent lumbar disc herniation (rLDH) is one of the major problems when surgically treating patients with LDH. Data on previous studies investigated the associations between facet joint parameters and rLDH appear only rarely in the literature. This study's objective was to evaluate the association between facet joint…

The increasing use of geographic information systems (GIS) in epidemiological population studies requires careful attention to the methods employed in accomplishing geocoding and creating a GIS. Studies have provided limited details,hampering the ability to assess validity of spatial data. The purpose of this paper is…

Development of a vaccine against herpes simplex virus type 2 (HSV-2), a life-long sexually-transmitted infection (STI), would be a major step forward in improving global sexual and reproductive health. In this review, we identified published literature of dynamic mathematical models assessing the impact of either proph…

We commend Zhao et al. for their insightful paper titled "Analysis of clinical characteristics of different types of lung function impairment in TDL patients," which compares the severity of lung function patterns, including restrictive and obstructive ventilatory patterns, with the clinical characteristics of tubercul…

Multiple agricultural productions were a way of life for Ethiopian farmers. However, it was known for low productivity due to improper resource allocation. Hence, the farm household is under food insecurity and earned a low annual income. To overcome these challenges, the present study used hierarchical-based cluster d…

Youth peer-support is an increasingly established approach to youth work. Drawing on Wenger's theory of a 'community of practice', this study explored social learning processes in an Australian community-based and peer-led youth program for young people from disadvantaged backgrounds. Social learning was conceptualised…

Losses to follow-up in clinical trials-patients for whom we do not know if the outcome of interest has occurred-can bias study results. If we investigate extreme case scenarios and find the study results do not change much, impact is negligible. If not, we may need to interpret the study's results with caution. At issu…

INTRODUCTION: In many fields, Artificial Intelligence (AI) has brought about paradigm change by enabling computer systems to do activities that were previously limited to human participation. OBJECTIVES: The study's primary focus is to evaluate responses generated through Chat-Generative Pre-Trained Transformer (ChatG…

OBJECTIVE: African Horse Sickness (AHS) is a vector-borne disease endemic to sub-Saharan Africa caused by African Horse Sickness Virus (AHVS). Infections in naïve horses have high morbidity and mortality rates. AHS pathogenesis is not well understood; neither the hematologic changes nor acute phase response occurr…

BACKGROUND: Lumbar radicular pain is often treated with interlaminar epidural particulate corticosteroid injection (ILEPSI). However, little literature exists on epidural tissue changes post ILEPSI. Investigating these potential tissue changes is valuable because of their possible clinical implications. OBJECTIVE: To…

The present review serves to highlight the antitumor worth of pyrazole derivatives. Several active pyrazole-based anticancer compounds proposed by a huge number of scientists worldwide are reported. Regarding the development of novel pyrazole-based anticancer agents at a faster tone, there is a need to correlate the la…

BACKGROUND: Uncontrolled hemorrhagic shock is a leading cause of early death after injury. Resuscitative endovascular balloon occlusion of the aorta (REBOA) represents a paradigm shift in achieving hemodynamic stability and its implementation still remain controversial in different settings. The recently published UK-R…

BACKGROUND: Sporadic intracranial vascular malformations can pose significant risk to parturients, and additional reports of management may inform patient care. Here we describe the peripartum management of parturients with intracranial vascular malformations. METHODS: After Institutional Review Board approval, we per…