11,351,761 papers found

INTRODUCTION: Research on workplace safety has seen significant growth in academic and industry-focused literature over the past 20 years. However, the extant literature on workplace safety tends to focus on safety outcomes of physical accidents and injuries while relegating its conceptual and theoretical development t…

C9orf72 is a major genetic factor in Amyotrophic Lateral Sclerosis (ALS), a neurodegenerative disorder affecting brain and spinal cord neurons, and comprehending its mutational impact is crucial for developing ALS therapies. Therefore, the current study's protein-protein interaction (PPI) network for C9orf72 was meticu…

The presence of potentially toxic metal(loid)s (As, Pb, Cd, Cr, Mn, Fe, Zn, Cu, Ni, Mo and Co) in 120 white (polished) rice grains (Oryza sativa; 2017 or earlier crop) purchased from farmers in the five most agriculturally active townships near Yangon in the eastern edge on Ayeyarwady Delta was determined by triple qua…

BACKGROUND: In 2021, an estimated 38 million people were living with human immunodeficiency virus (HIV) globally, with over two-thirds living in African regions. In South Africa, ~20% of South African adults are living with HIV. Accurate estimation of the risk factors and spatial patterns of HIV risk using individual-l…

The task of classification and localization with detecting abnormalities in medical images is considered very challenging. Computer-aided systems have been widely employed to address this issue, and the proliferation of deep learning network architectures is proof of the outstanding performance reported in the literatu…

BACKGROUND: γδT cells play an important role in the mucosa inflammation and immunity-associated disorders. Our previous study reported that γδ T cells producing IL-17 were involved in the pathogenesis of post-infectious irritable bowel syndrome (PI-IBS). However, their subset characteristic prof…

UNLABELLED: STUDY'S AIM: This study aims a more efficient follow-up of the safety of medicines with human usage on the Ivory Coast territory. METHOD: The structure responsible for pharmacovigilance in Ivory Coast i.e. DPM listed the medicinal alerts from 2001 till 2010. RESULTS: It emerges 237 medicinal alerts among…

Child maltreatment is a global public health and child rights crisis made worse by the ongoing COVID-19 pandemic. While understanding the breadth of the child maltreatment crisis is foundational to informing prevention and response efforts, determining accurate estimates of child maltreatment remains challenging. Alter…

A wide range of factors has detrimental impacts upon equity, diversity, and inclusion in clinical trials, amongst which participant burden can be significant. In addition to the potential physical burdens associated with investigational interventions, participants may face onerous demands related to factors like travel…

While traffic speed is a popular metric for evaluating road network efficiency and safety, its application is often limited. Studies typically focus on short stretches of road, specific design features, or particular highways, and even then, only during certain timeframes. This might be due to a lack of comprehensive t…

BACKGROUND: This study's aim was to quantify the carbon footprint of the 2023 American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting and compare it to an alternative meeting structure. MATERIALS AND METHODS: We conducted a retrospective analysis of estimated greenhouse gas emissions from the AAOS 2023 Annual M…

OBJECTIVES: Cochlear implant (CI) users struggle with music perception. Generally, they have poorer pitch discrimination and timbre identification than peers with normal hearing, which reduces their overall music appreciation and quality of life. This study's primary aim was to characterize how the increased difficulty…

OBJECTIVES: To evaluate the characteristics, assessment methods and overall impact of pharmacist-led interventions on medication adherence (MA) and clinical outcomes in patients with co-morbid hypertension and diabetes. METHODS: A predetermined search in four scientific databases (Scopus, Cochrane, Medline, and CINAHL…

BACKGROUND: The variations and patterns presented by inferior gluteal nerve (IGN) have been linked to iatrogenic complications, particularly in pelvic operations. The aim of this meta-analysis was to obtain data regarding IGN morphometry, communication and relationship with nervous structures of the gluteal area, cours…

INTRODUCTION: Elasticity is a biomechanical property of muscle necessary for physical function and can be measured with shear wave elastography (SWE). SWE may be useful in diagnosing pathology, predicting injury, and monitoring rehabilitation. This would be beneficial for smaller muscles working synergistically to resi…

BACKGROUND: Psychiatric disorders are the conditions that most contribute to incapacity worldwide. While many healthcare professionals adapt in dealing with various demands, others do not. How much of these conditions is associated with affective experience needs to be studied. OBJECTIVE: Assess the prevalence of anxi…

OBJECTIVE: Osteodiscitis has been demonstrated to show significant morbidity and mortality. Cultures and CT guided biopsy (CTB) are commonly used diagnosis of osteodiscitis. This study's purpose is to evaluate the cost burden of CTB and to evaluate how IVDU affects patient management in the setting of osteodiscitis. M…

Adolescent idiopathic scoliosis (AIS) is a spine deformity whose progression during growth is affected by asymmetrical loads acting on the spine. The conservative brace treatment aims to limit the deformity's progression until the end of skeletal growth. This study's objective was to develop a patient-specific finite e…

INTRODUCTION: The dorsal striatum, comprised of the caudate and putamen, is implicated in the pathophysiology of psychosis spectrum disorders. Given the high concentration of dopamine receptors in the striatum, striatal dopamine imbalance is a likely cause in cortico-striatal dysconnectivity. There is great interest in…

BACKGROUND: Low-grade fibromyxoid sarcoma (LGFMS) typically involves deep soft tissue (beneath the fascia) of the proximal extremities and trunk. Long-term follow-up has shown a high rate of local recurrence, metastasis, and death. To the best of our knowledge, there is only one previous large series focusing on superf…