42,208 papers found

Two new approaches in systematic reviewing i.e. Meta-narrative review(MNR) (which a health researcher can use for topics which are differently conceptualized and studied by different types of researchers for policy decisions) and Meta-triangulation review(MTR) (done to build theory for studying multifaceted phenomena c…

To assess the effect of JAK2V617F on different thrombotic risks in essential thrombocythemia (ET) patients, we identified eligible studies from several databases including Pubmed, Embase, and Cochrane Central Register of Controlled Trials (up to November 2014). Twenty-two studies of 2922 ET patients were included in ex…

This study aimed to determine the effectiveness of physical exercise in decreasing fatigue in cancer patients during active treatment. The PubMed Central, EMBASE, and OVID databases were consulted up to April 2014 to identify randomized clinical trials that evaluated the effect of exercise on fatigue in cancer patients…

BACKGROUND/AIMS: Recently, single-incision laparoscopic colectomy (SILC) for colorectal malignancy is rapidly becoming the central issue for explorers of minimally invasive surgery worldwide. The aim of this systematic review was to establish the safety and efficacy of SILC for colorectal malignancy when implemented by…

State/non-state partnerships in the health sector are of crucial importance in Nepal where partnerships between the Ministry of Health and Population (MoHP) and external actors have been fundamental to Nepal making progress in meeting millennium development goals. However, partnerships need to be strengthened.To gather…

There is a considerable debate on addiction and abuse to Smartphone among adolescents and its consequent impact on their health; not only in a global context, but also specifically in the Indian population; considering that Smartphone's, globally occupy more than 50% of mobile phones market and more precise quantificat…

BACKGROUND: Cognitive models of Social Anxiety Disorder suggest that negative self-images maintain social fears despite repeated exposure to benign social situations. An accumulating body of evidence supports this notion, and preliminary data indicate that modifying self-imagery can potentially reduce fears of negative…

PURPOSE: Proximal junctional kyphosis (PJK) is a common radiographic finding following long spinal fusions. Whether PJK leads to negative clinical outcome is currently debatable. A systematic review was performed to assess the prevalence, risk factors, and treatments of PJK. METHODS: Literature search was conducted on…

Areca nut is widely consumed by all ages groups in many parts of the world, especially south-east Asia. The objective of this review is to systematically review and collate all the published data that are related to the systemic effects of areca nut. The literature search was performed by an electronic search of the Pu…

PURPOSES: The purposes of this review were to discuss the role of exosomes in neurologic and psychiatric diseases and to propose future therapeutic approaches. METHODS: PubMed was searched (2000-2014) using the terms exosomes, microvesicles, neurological disorders, psychiatric disorders, multivesicular bodies, Alzheim…

BACKGROUND: The clinical case report has a long-standing tradition in the medical literature. While its scientific significance has become smaller as more advanced research methods have gained ground, case reports are still presented in many medical journals. Some scholars point to its limited value for medical progres…

OBJECTIVE: Patency capsule (PC) is a tool to screen the patency of the gastrointestinal (GI) tract. Capsule endoscopy can be performed after the patency is confirmed by the patency capsule. We aimed to estimate the diagnostic value of PC based on the existing trials. METHODS: We searched PubMed, CENTRAL and EMBASE for…

BACKGROUND: Endosonography [endoscopic ultrasound (EUS)-guided fine needle aspiration and endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration] is increasingly used for lung cancer staging and the assessment of sarcoidosis. Serious adverse events (SAE) have been reported in case reports, but the true…

Some studies have reported the importance of electroencephalography (EEG) as a method for investigating abnormal parameters in psychiatric disorders. Different findings in time and frequency domain analysis with regard to central nervous system arousal during acute panic states have already been obtained. This study ai…

OBJECTIVE: To evaluate the evidence on pre- and post-injury predictors of vocational outcome after traumatic brain injury (TBI). LITERATURE SELECTION AND CRITICAL ANALYSIS: The search was conducted on PubMed and Central databases since 1990. A clinical question was formulated according to the PICO framework. Clinical r…

OBJECTIVE: Chlorhexidine gluconate (CHG) is a common and safe antimicrobial agent and has been used widely in hand hygiene and skin disinfection; however, whether daily bathing with CHG results in the reduced acquired infection of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus…

OBJECTIVE: To evaluate the effectiveness of interventions on accelerating orthodontic tooth movement. MATERIALS AND METHODS: We searched the databases of PubMed, Embase, Science Citation Index, CENTRAL, and SIGLE from January 1990 to August 2011 for randomized or quasi-randomized controlled trials that assessed the ef…

OBJECTIVES: To provide an up-to-date review of the literature on the safety and efficacy of the endoscopic technique for cerebrospinal (CSF) leak repairs. DATA SOURCES: PubMed, Medline/Old Medline, and Cochrane Central databases. REVIEW METHODS: Using the above outlined data sources, studies involving the endoscopic…

UNLABELLED: A comprehensive literature search of Cochrane Library, PubMed, and Embase was performed to identify relevant prospective randomized controlled trials (RCTs) comparing biaxial microincision cataract surgery (MICS) and conventional coaxial phacoemulsification. A metaanalysis was performed on the following out…

A systematic review and meta-analysis was conducted to examine the effect of exercise training on daily physical activity (PA) in people with chronic obstructive pulmonary disease (COPD). MEDLINE, PubMed, EMBASE, CINAHL, Physiotherapy Evidence Database (PEDro) and Cochrane Central Register of Controlled Trials were sea…