98,297 papers found

OBJECTIVES: To examine changes in the prevalence of smoking in young adult diabetic patients between 1990 and 1999. SETTING: Walton Diabetes Centre, University Hospital Aintree, Liverpool, UK. DESIGN: Direct questioning as well as the urinary cotinine:creatinine ratio were used to assess the smoking habits of 99 youn…

PURPOSE: In industrialized countries the prevalence of upper urinary tract stones has continually increased during the 20th century, but there are considerable differences between countries and also within the same country. To study whether there is still an increase in the frequency of renal stones, an investigation w…

The statistical study of a large number of eclamptic patients (n = 704), divided into five successive 3-year periods, was undertaken at the Hospital de Gineco-Obstetricia No. 2 del Centro Médico Nacional in Mexico City in orders to detect significant changes in therapeutic results and/or in the basic character of…

BACKGROUND: Anthracycline cytostatics, widely used in oncologic practice, may induce discrete myocardial damage occasionally culminating in life-threatening cardiologic complications. The most serious clinical manifestations of anthracycline cardiotoxicity are dilated cardiomyopathy, heart failure and fatal arrhythmias…

We assess early clinical and radiographic results of a multicentric and prospective study of 485 Summit porous-coated stems implanted in 5 hospitals. Of the patients, 171 had a hydroxyapatite (HA) coating and 314 had non-HA porous-coated stems. The mean follow-up was 4.2 years (range 2.5-6 years). The median size of th…

Fifty-three patients with primary bladder carcinoma underwent total cystectomy during the past 10 years. Ages ranged from 32 to 87 years old, with an average of 68.2 years. Radical total cystectomy, including systemic lymphadenectomy was performed in 22 cases, simple total cystectomy in 8 cases and salvage total cystec…

OBJECTIVE: To study the clinical and immunological profile of children with juvenile rheumatoid arthritis (JRA). DESIGN: Retrospective hospital based study. SETTING: Tertiary level center of North India. SUBJECTS: 74 patients attending the Pediatric Rheumatology and Immunology Clinic over last 5 years. RESULTS: The…

The presence of subgingival pathology, such as a deep secondary caries lesion, a fracture, an already existing restoration that needs to be replaced or the presence of a resorption defect, can constitute a difficult starting situation for the preservation of a tooth. How to deal with such a situation has been a topic o…

Microsurgery has broad applications in reconstructive surgery. As techniques, diagnostics, and advancing technology rapidly evolve, reconstructive microsurgeons can adapt to address new challenges and push the frontiers to achieve optimal functional and aesthetic reconstruction, and minimize donor site morbidity. This…

Cancer-related mortality have been declining in the last decades. Approximately half of adults and more than two thirds of children oncological patients live longer than 5 years after diagnosis. However, this optimistic scenario has been counterbalanced by an increasing cardiovascular risk in cancer patients. Atheroscl…

Lipid nanocapsules (LNCs) were designed more than 15 years ago to deliver lipophilic drugs to cells with non toxic excipients by mimicking lipoproteins. During the last 5 years these promising nanocarriers were re-designed to deliver nucleic acids to cancer cells. This short review sums up the features of LNCs and desc…

The bioethics law of 2004 prohibited any research on the human embryo but authorized by way of derogation this one. The French biomedicine agency was charged to take care of the scientific, legal respect and ethics of this research, via its council of orientation. In 5 years it took more than 100 decisions on this subj…

Malaria is one of the most widespread infectious diseases of our time, causing 655 000 deaths during 2010 (WHO), most of them in sub-Saharan Africa and under the age of 5. During the last few years an increasing number of imported malaria cases is reported in Europe and Mediterranean countries, probably supported by th…

This article will review current knowledge germane to understanding estimations of survival time of persons following severe traumatic brain injury (STBI). Nomenclature issues relevant to biostatistics and the neuroscientific investigation of survival after STBI will also be explored. Biostatistical methods used for de…

AIMS: The overweight and obesity epidemic among children in Australia has attracted considerable attention as intervention strategies and public policy are debated. However, more information on the overweight prevalence trend is required to help understand its aetiology. In order to assist this public health crisis, we…

Our 10-year experience of retroperitoneal laparoscopic pyelolithotomy, a rarely performed minimally invasive operative procedure, is presented. The results are compared with our own experience of percutaneous nephrolithotomy for larger renal stones. Forty-two patients with a mean age of 39.12 years underwent 43 retrope…

Resolution and penetration are primary criteria for clinical image quality. Conventionally, high bandwidth for resolution was achieved with a short pulse, which results in a tradeoff between resolution and penetration. Coded excitation extends the bounds of this tradeoff by increasing signal-to-noise ratio (SNR) throug…

The chemistry of metal carbene complexes has experienced an enormous development in the past decades. Despite this fact, the use of transition metals as catalysts in reactions involving group 6 Fischer carbene complexes was virtually neglected. Here, we describe how the reactivity of these compounds can be enhanced or…

Thirteen consecutive patients with thalamic deep brain stimulation (DBS) were examined serially for 3 to 5 years. Initially, all demonstrated at least 50% improvement in contralateral tremor. At last follow-up, three of eight patients with Parkinson disease no longer used DBS because tremor had markedly improved, and f…