Diurnal variations to proinflammatory markers in individuals with diabetes compared to healthy controls: protocol for a systematic review and meta-analysis.
Reid Anna Grace, Wu Ching Yi, Nguyen Thi Hoang Oanh, +3 more·BMJ open
INTRODUCTION: Diabetes mellitus is a highly prevalent metabolic disorder associated with chronic, low-grade inflammation. Of recent interest is the association between diabetes and circadian rhythm disruption. The aim of this review is to evaluate and synthesise clinical evidence for whether diabetes affects homeostati…