98,289 papers found

The aim of our study was to evaluate the evolution of glucose metabolism in 57 patients after treatment of their acromegaly and to determine risk factors for the persistence of abnormal glucose tolerance. Therefore, we performed IGF-I measurements, oral glucose tolerance tests (OGTTs), and HOMA to evaluate insulin sens…

Proprioceptive neuromuscular facilitation (PNF) is an attractive method to increase strength and proprioception of elderly individuals. However, a major clinical concern about the prescription of PNF is the belief that it can cause a cardiovascular overload, because it involves close-to-maximal loads and isometric cont…

OBJECTIVE: To compare functional and oncologic outcomes in elderly (&#x2265;&#x2009;70&#x2009;years) and nonelderly (<&#x2009;70&#x2009;years) patients after transoral robotic surgery (TORS). METHODS: A retrospective chart review was conducted on 114 patients who underwent TORS for head and neck squamous cell carcinom…

OBJECTIVE: To introduce the satellite rod technique utilized in severe spinal deformity after three-column osteotomy (3CO) and to evaluate the radiographic and clinical outcomes at 2-year follow-up, further discussing its utilization in this particular cohort. METHODS: A total of 32 (19 females and 13 males) with an a…

We investigated the evolution of the families of LINE-1 (L1) retrotransposons that have amplified in the human lineage since the origin of primates. We identified two phases in the evolution of L1. From approximately 70 million years ago (Mya) until approximately 40 Mya, three distinct L1 lineages were simultaneously a…

UNLABELLED: During the last years in vitro investigations have demonstrated the possibility of nitrosation of different amines and amides including a number of drugs. The aim of the presented investigations was to test whether an endogenous nitrosation of piperazine, Obesin (propyhexedrine), and ephedrine is possible i…

OBJECTIVE: Therapies for chronic kidney disease have changed greatly over the last decade. The aim of this study was to examine the changes in the clinical characteristics and carotid atherosclerosis of patients with end-stage kidney disease (ESKD) over the last 9 years. METHODS: A cross-sectional study of 150 consecu…

To evaluate the safety and efficacy of stent-assisted coil embolization in patients with recurrent intracranial bifurcation aneurysms,after initial simple coiling or microsurgical clipping.Clinical data of 20 patients with recurrent intracranial bifurcation aneurysms who initially underwent simple coiling or surgical c…

Indoor residual spraying (IRS) and long-lasting insecticide-treated bednets (LLINs) are common tools for reducing malaria transmission. We studied a cohort in Uganda with universal access to LLINs after 5 years of sustained IRS to explore LLIN adherence when malaria transmission has been greatly reduced. Eighty househo…

OBJECTIVE: To investigate the burden of asthma in a young adult population in urban areas of Argentina. DESIGN: A nationwide telephone survey in subjects aged 20-44 years was performed in urban areas in Argentina. The European Community Respiratory Health Survey questionnaire was used. Asthma was defined as an exacerb…

OBJECTIVE: To explore use and attitudes toward drugs and dietary supplements (DS) and knowledge concerning doping in cycling. DESIGN: Retrospective cross-sectional study. SETTING: Professional cycling. PARTICIPANTS: Elite under-23 male cyclists. INTERVENTION: Anonymous semistructured questionnaire administered duri…

BACKGROUND: Distal chevron osteotomy (DCO) for mild to moderate hallux valgus deformity is inherently more stable than the other forms of distal metatarsal osteotomy, but complications such as loss of correction, infection, joint stiffness, delayed union, malunion and nonunion can occur. In this study, we evaluated the…

From a random digit dialing survey of American women, we assessed current smokers (n=371). Respondents were 33.6+/-7.6 years old, 49.6% married, and 87.6% White, with an FTND score of 3.9+/-2.6. When asked "which cigarette of the day would be the most difficult for you to give up?" 30 women gave uncodable responses and…

Over the last nine years, several quantitative polymerase chain reaction (QPCR) techniques have been developed, and these are now frequently used for the quantification of DNA template copy numbers. However, only few of these PCR techniques are suitable for the precise and absolute quantification of the template copy n…

Twenty-four patients with chordoma who received one or more courses of megavoltage radiation therapy following biopsy or incomplete resection were reviewed. The uncorrected survival rate at five years was 62%, and at 10 years was 28%, but most patients had clinically detectable residual chordoma present at the time of…

Fifty patients with Marfan's syndrome underwent operation at the National Heart Hospital because of cardiovascular complications. Forty-six had an aneurysm of the ascending aorta, 13 had chronic dissection, and 6 had acute dissection of the aortic wall. Forty-three aortic valves were incompetent, and five were stenotic…

Tuberculosis is a serious health problem in India, but because of inadequate facilities for diagnosis in many parts of the country clinical data are incomplete. However, data on prevalence are available from a few sample surveys conducted in the general population during the last two decades. The study reported here pr…

INTRODUCTION: Phenyl ketonuria is an inborn error of amino acid metabolism resulting in excessive phenyl alanine levels in blood resulting in a spectrum of neurological defects. PATIENTS AND METHODS: We retrospectively went through the records of patients diagnosed as Phenyl ketonuria in the last nine years in our tea…

Does the dogma that multiple myeloma is incurable still hold?. The genomic chaos and resulting resistance to apoptosis of myeloma, long considered an obstacle to cure, formed the basis of Total Therapy (TT) program. The TT approach uses all myeloma-active drugs upfront to target drug-resistant subclones during initial…

BACKGROUND: Survival in acute myeloid leukemia (AML) has improved in younger patients over the last decade. This study was conducted to evaluate the relative survival rates in older AML patients over two decades in the US. MATERIAL AND METHODS: We analyzed Surveillance, Epidemiology, and End Results (SEER) registry da…