Searching PubMed for “Meta-analysis” and checking full-text availability…
for “Meta-analysis” · Showing 941–960 · 3100 ms
van Gijn J·Neurologic clinics
Until recently, a gap existed between the rapidly advancing knowledge about the pharmacology of aspirin and the management of patients who are threatened by stroke. In doses as low as 20 to 40 mg per day, aspirin can completely suppress the production of the aggregant agent thromboxane A2. The clinical evidence, howeve…
Poulter N·American heart journal
Hypertension intervention trials, which have involved mainly the use of diuretics and beta-blockers, have demonstrated a disappointing benefit in terms of reduction of coronary heart disease (CHD). Rather than suggesting that elevated blood pressure and CHD are not causally related, these data suggest that the antihype…
Levine B A, Sirinek K R·The Surgical clinics of North America
This article has attempted to question whether the more recently introduced methods of treating the patient with variceal hemorrhage have resulted in higher salvage rates and a better quality of life. Data concerning other types of central shunts, selective shunting, nonshunt operations, hepatic transplantation, sclero…
Ross P D, Davis J W, Vogel J M, +1 more·Calcified tissue international
The usefulness of various bone mineral measurement techniques is a subject of current controversy. In order to explore whether disparate conclusions may have arisen from differences in analytic methodology, data from published reports of bone mass and nonviolent fractures have been reanalyzed in terms of fracture risk.…
Ramos-Campo Domingo J, Foster Carl, Andreu-Caravaca Luis, +2 more·Sports medicine (Auckland, N.Z.)
BACKGROUND: Pacing strategy is a key determinant of endurance performance, enabling athletes to regulate effort to optimise outcomes. While various pacing profiles (e.g. self-selected, fast-start, even, or slow) have been proposed, their comparative effects on performance remain unclear because of conflicting findings…
Hasan Faizul, Gordon Christopher James, Yuliana Lia Taurussia, +2 more·Worldviews on evidence-based nursing
BACKGROUND: The comparative efficacy of brief behavioral therapy for insomnia (BBTI) remains unclear. AIMS: This systematic review and network meta-analysis examined the effectiveness of different BBTI approaches and compared BBTI with other nonpharmacological interventions, such as cognitive behavioral therapy for in…
Azimi Amir, Toloui Amirmohammad, Mozafarybazargany Mohammadhossein, +10 more·Spinal cord
STUDY DESIGN: An Umbrella Review and Meta-analysis. OBJECTIVE: This umbrella review and meta-analysis aims to evaluate the efficacy of stem cell therapy for locomotion recovery and neuropathic pain alleviation in rodent models of spinal cord injury (SCI). METHODS: A comprehensive literature search was conducted in Me…
Alley Stephanie J, Waters Kim M, Parker Felix, +4 more·The international journal of behavioral nutrition and physical activity
BACKGROUND: Physical activity is important for healthy ageing, however most older adults are inactive. Numerous reviews with a range of inclusion criteria have been conducted on digital interventions to promote physical activity in older adults, and a synthesis of these is needed. Therefore, the objective of this study…
Burzotta Francesco, Testa Luca, Giannico Floriana, +11 more·International journal of cardiology
OBJECTIVES: To overview and summarize the results emerging from the studies on adjunctive devices (AD) with theoretical anti-embolic properties in patients with ST-elevation acute myocardial infarction (STEMI) undergoing percutaneous coronary interventions (PCI). BACKGROUND: A series of small-to-medium size randomized…
Gore S M, Fontaine O, Pierce N F·BMJ (Clinical research ed.)
OBJECTIVE: To define the benefit of rice oral rehydration salts solution in relation to the glucose based World Health Organisation oral rehydration salts solution for treating and preventing dehydration in patients with severe dehydrating diarrhoea. DESIGN: Meta-analysis using data from 13 available randomised trials…
Beasley C M, Dornseif B E, Bosomworth J C, +6 more·BMJ (Clinical research ed.)
OBJECTIVE: A comprehensive meta-analysis of clinical trial data was performed to assess the possible association of fluoxetine and suicidality (suicidal acts and ideation). DESIGN: Retrospective analysis of pooled data from 17 double blind clinical trials in patients with major depressive disorder comparing fluoxetine…
Naeini Fatemeh, Zeraattalab-Motlagh Sheida, Rahimlou Mehran, +5 more·The British journal of nutrition
Multiple reviews have examined the impact of nutritional interventions in patients with burn injuries; however, discrepancies among results cast doubt about their validity. We implemented this review to assess the impact of various nutritional interventions in adult patients with burn injuries. We conducted a thorough…
Batrakoulis Alexios, Perivoliotis Konstantinos, Courneya Kerry S, +6 more·Medicine and science in sports and exercise
PURPOSE: This network meta-analysis aimed to evaluate and rank the comparative efficacy of aerobic training (AT), resistance training (RT), combined AT and RT (CT), and high-intensity interval training (HIIT) primarily on body weight and secondarily on body mass index (BMI), fat-free mass, fasting glucose, fasting insu…
Martins Adrielly, Khakoo Nidah S, Reddy Anish, +6 more·Hepatology (Baltimore, Md.)
BACKGROUND AND AIMS: Primary biliary cholangitis is a chronic cholestatic liver disease that may progress to cirrhosis and liver failure. For patients with inadequate response or intolerance to ursodeoxycholic acid, peroxisome proliferator-activated receptor (PPAR) agonists have emerged as second-line options. This stu…
Oon Isobel H, Lynch Joseph T, Lindsay Cody, +3 more·The Journal of arthroplasty
BACKGROUND: Despite surgically successful total knee arthroplasties, up to 20% of patients are dissatisfied postoperatively. A factor thought to influence dissatisfaction is the alignment strategy utilized. Inconsistencies in safe zone definitions between neutral and kinematic alignment strategies have limited previous…
Rushton L, Jones D R·British journal of obstetrics and gynaecology
OBJECTIVE: To review published reports of risk of breast cancer with oral contraceptive use. DESIGN: Meta-analysis of study results, using regression techniques to explore the inter-study heterogeneity. SETTING: Twenty-seven epidemiological studies of breast cancer risk and oral contraceptive use published 1980-1989.…
Czekelius P, Wenzel H·Zeitschrift fur Geburtshilfe und Neonatologie
INTRODUCTION: Crowther et al. 3 analysed the effectivity of magnesium tocolysis in preventing preterm birth. They conclude that there is no evidence for protection. In its latest guidelines, based on this Cochrane analysis, the German Association of Gynaecology and Obstetrics (DGGG) does not recommend any more the use…
Pandis Nikolaos, Fleming Padhraig S, Worthington Helen, +1 more·PloS one
OBJECTIVES: The main objective was to assess the credibility of the evidence using Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) in oral health systematic reviews on the Cochrane Database of Systematic Reviews (CDSR) and elsewhere. STUDY DESIGN AND SETTING: Systematic Reviews or meta-analys…
Biondi-Zoccai Giuseppe G L, Lotrionte Marzia, Abbate Antonio, +7 more·BMJ (Clinical research ed.)
OBJECTIVE: To appraise multiple systematic reviews on the same clinical topic, focusing on predictors and correlates of quality of reporting of meta-analysis (QUOROM) scores. DESIGN: Case study. SETTING: Reviews providing at least individual quantitative estimates on role of acetylcysteine in the prevention of contra…
Ioannidis John P A, Trikalinos Thomas A·Journal of clinical epidemiology
BACKGROUND AND OBJECTIVE: Divergent results on the same scientific question generate controversy. We hypothesized that controversial data are attractive to investigators and editors, and thus the most extreme, opposite results would appear very early rather than late, as data accumulate, provided data can be generated…