The Role of Peripheral N-Methyl-D-Asparate (NMDA) Receptors in Itch and Pain: A Narrative Review.
Tanaka Ryusuke, Lo Vecchio Silvia, Aliotta Giulia Erica, +1 more·European journal of pain (London, England)
BACKGROUND AND OBJECTIVE: NMDA receptors, predominantly located in the central nervous system and known for their roles in synaptic plasticity and central sensitisation of pain and itch, are also expressed in peripheral sensory neurons. Emerging evidence suggests that peripheral NMDA receptors contribute to pathologica…