11,351,068 papers found

One of the goals of imprisonment is to reduce violence. Although imprisonment has risen dramatically since the 1970s, its effects on future violent crime are poorly understood. This study's objective was to examine the effect of imprisonment on violent crime in the community among individuals on the policy margin betwe…

BACKGROUND/AIM: Graves’ disease (GD) is more severe, requires a more complex treatment, and has a lower probability of achieving remission in children than in adults. There is no consensus on the appropriate duration of antithyroid drug (ATD) treatment. Surgical or radioactive iodine (RAI) treatments are not def…

Although beta-blockade itself is not a first choice for chronic kidney disease (CKD) patients, alpha-beta-blockers (ABB) do improve their prognoses. This study's aim was to evaluate the effect of beta-selective-blockers (BSB) and ABB on circadian cardiac autonomic activity in CKD patients.The study consisted of 496 non…

AIM: Naval Medical Center San Diego's Psychiatric Transition Program is a specialized first episode psychosis treatment program that delivers coordinated specialty care to military service members with psychotic disorders. Due to the unique military environment, military service members with first episode psychosis are…

BACKGROUND: Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder caused by loss-of-function mutation in the NF1 gene. Segmental or mosaic NF1 (MNF) is an uncommon presentation of the NF1 result of postzygotic mutations that present with subtle localised clinical findings. OBJECTIVES: Our study's objectives were…

PURPOSE: This study's purpose was to investigate the prevalence of dental fluorosis in children, whose parents had participated in an oral health program when the children were between zero and three years old, residing in a city with fluoridated water. METHODS: Group 1 consisted of 128 eight- to 12-year-olds whose pa…

BACKGROUND: Most previous research that has examined mental health among Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF) combatants has relied on self-report measures to assess mental health outcomes; few studies have examined predictors of actual mental health diagnoses. The objective of this longitud…

AIM: The study's objectives were to characterize initiation of injection drug use, examine the independent association of specific substance use with injection drug use and determine factors associated with rates of transition from first illicit drug use to first injection among a sample of rural Appalachian drug users…

BACKGROUND: In-vitro fertilization (IVF) with blastocyst as opposed to cleavage stage embryos has been advocated to improve success rates. Limited information exists on which to predict which patients undergoing blastocyst embryo transfer (BET) will achieve pregnancy. This study's objective was to evaluate the predicti…

PURPOSE: To evaluate the association between urinary and blood cadmium (Cd) levels with age-related macular degeneration (AMD). DESIGN: Prospective case-control study. METHODS: In 53 participants older than 60 years with AMD in both eyes and in 53 age-matched (+/- 3 years) controls without AMD, Cd levels were measure…

PURPOSE: The study's purpose was to determine the prevalence and prognostic importance of acute, severe, noncardiac conditions present at the time of an acute myocardial infarction (AMI). METHODS: We identified consecutive patients with AMI who were discharged from Yale-New Haven Hospital between January 1, 1997, and…

The highly infectious novel coronavirus (COVID-19), officially SARS-CoV-2, was discovered in Wuhan, China, and quickly spread to the rest of the world in 2020. Frontline workers had frequent interactions with COVID-19-infected and -uninfected patients. Therefore, the study's overarching goal is to investigate the exper…

Sample size calculations for trials with time-to-event outcomes are usually based on the assumption that an event - prototypically death in survival analysis - occurs only once per sample unit. However, events like changes in disease status or switches between treatment modalities may repeat over time. In trials with s…

The purpose of this investigational study was to assess the cardiovascular effects of melatonin replacement therapy in pinealectomized patients. This was a prospective open-label, single-arm proof-of-concept study The study comprised 11 patients aged 16.7 ± 1.7 years, who had undergone pinealectomy,…

INTRODUCTION: The increase of young and middle-aged adult patients with multimorbid and/or complex chronic conditions has created new challenges for healthcare systems and services. Advanced Practice Nurses (APNs) play an essential role in treating these patients because of their expertise and advanced nursing skills.…

Following Indonesian criminal law, courts may not find defendants or offenders guilty for various grounds known as illegal abolition reasons. There are two justifications and grounds for forgiveness for abolishing crimes under the Indonesian Criminal Code. The justification for abolishing this punishment is solely appl…

Dapivirine (DPV) is a potent NNRTI used to prevent the sexual transmission of HIV. In a phase 1 trial (IPM 028), the concomitant use of a DPV vaginal ring and an antifungal miconazole (MIC) vaginal capsule was found to increase the systemic exposure to DPV in women, suggesting a potential for drug-drug interactions. Th…

Staphylococcus aureus is an important human pathogen with an arsenal of virulence factors and a propensity to acquire antibiotic resistance genes. The understanding of the global epidemiology of S. aureus through the use of various typing methods is important in the detection and tracking of novel and epidemic clones i…

BACKGROUND: With the prevalence of mental issues worldwide, more and more people are suffering from psychological torture. Mental Health Gap Action Program (mhGAP) has been introduced to improve the life quality of humans. OBJECTIVES: To explore and synthesize evidence of participants' experience of mental health firs…

BACKGROUND: Arrhythmia is an abnormal sinus rhythm of the heartbeat, and in addition to threatening the patient's health, it may also cause fatal complications. OBJECTIVES: The present review study was investigated the effects of berberine (BBR) on cardiac arrhythmias and its possible complications. METHODS: A system…