Trial of the antiviral action of isoprinosine against rhinovirus infection of volunteers.
Soto A J, Hall T S, Reed S E·Antimicrobial agents and chemotherapy
Isoprinosine (NPT-10381) was given orally to a group of 22 volunteers at a daily dose of 6 g for 7 days; a control group of 23 volunteers received placebo. Volunteers were inoculated intranasally with both rhinovirus type 9 and rhinovirus type 31, and the clinical picture, extent of virus shedding, and serological resp…