11,527,996 papers found

Are your data collection efforts for naught? A recent study shows that employers and purchasers overlook provider outcomes data and quality report cards when choosing health plans and providers--opting instead for customer satisfaction, HEDIS, and cost data. Here are the details on the study, plus advice from one of th…

OBJECTIVE: Infants' sleeping patterns can influence parents' sleep and their well-being. Infants' sleeping problems can evoke negative emotions from their parents because of the influence the problems have on parents' lives. However, little is known regarding the associations between infants' night sleep patterns and p…

The design of randomized controlled clinical studies can greatly benefit from iterative assessments of population representativeness of eligibility criteria. We propose a multi-trait metric - GIST 2.0 that can compute the a priori generalizability based on the population representativeness of a clinical study by explic…

Given the crisis of representation (of) and complicated histories of othering, ethnography seems to be a methodology in need of cripping. Autoethnography, then, is one approach to solve said crisis of representation. Down to classics like Robert Murphy's, Disability Studies often use authors' autobiographical experienc…

A properly formulated diet is an essential underpinning for all in vivo research. This chapter focuses on the use of diet in retinoid research from two perspectives: human research, in which diet is usually variable and analysis of dietary intake is paramount to interpreting the study's results, and animal (rodent) res…

The cell-based assay using yeast deletion mutants has been recognized as an efficient analysis to discover therapeutic compounds and reveal their mode of action. In this study, S. pombe deletion mutants-based HTS screening was carried out to identify potential anti-cancer agents. The NCI chemical library of 5700 compou…

Preliminary data [S. Burstein and S. A. Hunter, Biochem. Pharmac. 27, 1275 (1978)] showed that cannabinoids at levels of 1 microM or greater elevated the concentrations of prostaglandins in cell culture models. Further study [S. Burstein and S. A. Hunter, J. clin. Pharmac. 21, 240S (1981)] led to the suggestion that th…

The primary non-rodent species used in toxicology is the dog. It is generally agreed that, for ethical reasons, dog use should be reduced to the minimum consistent with maintaining the scientific quality of toxicology studies and ensuring human safety. Dog use in toxicology has been discussed widely, both from a scient…

This study used an expanded technology acceptance framework that takes compliance and safety into account to investigate the uptake of Robotic Process Automation (RPA) in the transportation industry. To put this all-encompassing model to the test, we surveyed 190 people who work in the transportation industry. The resu…

Brain involvement in myotonic dystrophy type 1 (DM1) is characterized by heterogeneous cognitive, behavioral, and affective symptoms and imaging alterations indicative of widespread grey and white matter involvement. The aim of the present study was to systematically review the literature on brain pathology in DM1. We…

To date, the scientific process for generating, interpreting, and applying knowledge has received less informatics attention than operational processes for conducting clinical studies. The activities of these scientific processes - the science of clinical research - are centered on the study protocol, which is the abst…

The lesbian, gay, bisexual, transgender, and queer (LGBTQ) population deals with complex medical and behavioral issues coupled with barriers in accessing both healthcare and health insurance leading to poorer health outcomes as compared with the general population. Because this community is often overlooked in efforts…

Errors in classifying individuals as to whether they have a certain characteristic may adversely affect the power of a statistical test to detect differences in the incidence of that characteristic between groups or to detect changes in the incidence over time. To determine whether the classification method to be used…

This study investigated the relationship between individual and job characteristics of mental health social workers and professional dissonance--an experienced conflict between values and job tasks. A 33-item questionnaire, designed specifically for the study's purposes was utilized. A total of 320 usable study questio…

OBJECTIVE: We sought to determine how often non-English-speaking (NES) persons are excluded from medical research. DESIGN. Self-administered survey. PARTICIPANTS: A Medline search identified all original investigations on provider-patient relations published in major U.S. journals from 1989 through 1991, whose methodo…

Recent studies show that students' fraction knowledge predicts their later algebra knowledge. This longitudinal study investigated whether this relationship is bidirectional-that is, whether early algebra knowledge predicts later fraction knowledge-and whether early algebra knowledge improves during fraction instructio…

This retrospective cohort study was designed to investigate the relationship of male occupational exposure to elemental mercury and several reproductive outcomes. All subjects worked at least 4 months between 1953 and 1966 at a plant that used elemental mercury; 247 white male employees who had the highest exposures we…

Performance appraisal (PA) is used for various organizational purposes and is vital to human resources practices. Despite this, current estimates of PA reliability are low, leading to decades of criticism regarding the use of PA in organizational contexts. In this article, we argue that current meta-analytical interrat…

Dementia is a neurodegenerative disease that causes a progressive deterioration of thinking, memory, and the ability to perform daily tasks. Other common symptoms include emotional disorders, language disorders, and reduced mobility; however, self-consciousness is unaffected. Dementia is irreversible, and medicine can…

The therapeutic effectiveness of acupuncture relies on both safety and stability, making these factors essential in acupuncture manipulation research. However, manual manipulation introduces unavoidable inaccuracies, which can impact the reliability of research findings. To address this challenge, a unique lifting and…