381,592 papers found

OBJECTIVE: To assess the effects of anabolic-androgenic steroids on human muscle strength. DATA SOURCES: A MEDLINE search for the period from January 1966 to April 1990, supplemented by manual searches of previous reviews, produced 30 studies in which subjects received more than one dose of the study steroid and in wh…

Fifty nine scientific papers had been published in english or french literature, by 1988, on the matter of respiratory health effects of environmental tobacco smoke exposure (ETS). Fifteen dealt with lung cancer. An original meta-analytical approach was used in order to assess the consistency of these results, where th…

Optimization of radiation therapy for head and neck tumors requires the combination of several facets of radiation biology and physics. The aim is to achieve optimum tumor control while reducing normal tissue damage. Techniques have been developed to determine tumor radiosensitivity and growth characteristics. Their us…

In order to evaluate the variability in the diagnostic accuracy of the exercise electrocardiogram, a meta-analytic database derived from a review of 147 publications and a multicenter database derived from 2,826 angiographic referrals were analyzed. Wide variability in sensitivity and specificity were found from the me…

We systematically reviewed the six articles from the English-language medical literature, since 1979, which compared 99mTc-RBC venography with contrast venography for the diagnosis of deep venous thrombosis (DVT) of the lower extremity. The studies were generally small in size and poorly compliant with methodologic sta…

Age at the start of breast development and at menarche are important maturity indicators in adolescent females. Breast development is usually the first event of puberty and menarche virtually the last. Irregularities in the age of the subject at their appearance can denote a lack of synchronisation between pubertal eve…

Because fungal infection is a significant factor that determines the morbidity and the mortality of many patients with cancer, it is essential to understand the various predisposing defects that lead to such infections. These defects may be categorized into two broad areas: immune defects and mechanical defects. Among…

We conducted a survey of clinical trials to assess the scientific evidences presented for the practical use of dinitrochlorobenzene, squaric acid dibutylester, and diphencyprone in the treatment of alopecia areata. Twenty-six papers published between January 1977 and January 1988, in English, French, and Italian were s…

Due to the recent development of absorbable surgical staples, application of gynecologic stapling methods has expanded to the field of obstetrics. Several studies have been published presenting the results of utilization of a novel hysterotomy and uterine stapling device for cesarean section (Poly CS-57, U.S. Surgical…

INTRODUCTION: Noncompressible torso hemorrhage (NCTH) is a major cause of preventable death in both civilian and military trauma settings. It involves vascular disruptions within the thoracic cavity, major axial torso vessels, severe solid organ injuries, or pelvic ring fractures leading to hemodynamic instability resi…

Currently, an increasing number of individuals diagnosed with diabetes mellitus (DM) are opting for combined functional substances in edible plant products, like herbal prescription or traditional Chinese medicine (TCM), to enhance the efficacy of blood glucose and lipid profile control. Among various TCM-included trea…

BACKGROUND: Given the lack of head-to-head studies of approved biologic therapies in hidradenitis suppurativa (HS), a chronic, recurrent inflammatory skin disease, a systematic literature review (SLR) and network meta-analysis (NMA) were conducted to provide insight into their comparative short-term efficacy. OBJECTIV…

OBJECTIVES: Emerging evidence suggests that glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose co-transporter 2 (SGLT2) inhibitors may exert neuroprotective effects. However, the comparative efficacy of individual agents remains unclear. This network meta-analysis (NMA) aimed to evaluate the different…

CONTEXT: Continuous energy restriction (CER) and intermittent fasting (IF) are both prevalent diet regimens recommended for weight loss and metabolic improvement. OBJECTIVE: The objective of this study was to evaluate the efficacy of CER and IF on weight loss and metabolic improvement in adults with overweight, obesit…

As evidence-based practitioners become more reliant on systematic reviews to inform treatment, it becomes important to systematize reporting details as well as improve the quality of the primary studies that will later be incorporated into this secondary literature. In this article, the authors consider several specifi…

The aim of this study was to examine the distribution of caries on different tooth surfaces, at varying levels of dental caries, in adolescent populations. Using data obtained from published reports, the relationship between reported mean surface-type caries scores were plotted against the total mean DFS and showed a g…

OBJECTIVE: Reports of pharmacy research using crossover designs were reviewed to determine if the studies adequately consider interaction effects and use appropriate statistical analyses. DATA SOURCES: All crossover studies published in DICP, The Annals of Pharmacotherapy during 1988 and 1989 were analyzed. STUDY SEL…

In order to elucidate factors affecting the rate of angioplasty restenosis, we reviewed 212 published reports on restenosis after percutaneous transluminal coronary angioplasty. We used five specific methodologic standards to select the 31 reports most likely to produce unbiased results. Sixty one factors judged to be…

The purpose of this quasi-experimental study was to determine if the patency of the peripheral intermittent intravenous device (PIID) would be maintained as effectively with a sodium chloride solution as with a dilute heparin solution and to determine if a sodium chloride solution could be used with fewer local complic…

The present review examines the relationship between disaster occurrence and psychopathology outcome for 52 studies that used quantitative measures of such a relationship. Descriptive and inferential techniques were used to examine relationships among four sets of variables: (a) the characteristics of the victim popula…