4,952,562 papers found

BACKGROUND: Mesenchymal stem cells (MSCs) are multipotent cells that demonstrate therapeutic potential for the treatment of acute and chronic inflammatory-mediated conditions. Especially for acute conditions, it is critical to have a readily available freshly thawed (cryopreserved) MSC product for rapid administration.…

INTRODUCTION: The research literature addressing pre-exposure prophylaxis (PrEP) has increased considerably over the last decade. To better understand the research areas and explore research gaps, we will conduct a scoping review to map study topics and describe study characteristics and populations in publications foc…

BACKGROUND: Integrated reminders within clinical systems have become more prevalent due to the use of electronic health records and evidence demonstrating an increase in compliance within practice. Clinical reminders are assessed for effectiveness on an individual basis, rather than in combination with existing prompts…

Musculoskeletal injuries are a common presentation to the ED, with significant costs involved in the management of these injuries, variances in care within the ED and associated morbidity. A series of rapid review papers were completed to guide best practice for the assessment and management of common musculoskeletal i…

BACKGROUND: Pediatric brain tumors are the most common solid tumors in children. Advances in understanding the hallmarks of cancer biology and novel therapies have led to an increasing number of survivors of childhood brain tumors (SCBT). However, these survivors are at an increased risk of obesity and cardiometabolic…

OBJECTIVE: The aim of this review is to map and summarize metacognitive interventions for adolescents with mental health disorders. INTRODUCTION: Metacognitive interventions are widely implemented in adults across various types of mental health disorders. Use in adolescents (aged between 10 and 19 years) has alre…

Searching multiple resources to locate eligible studies for research syntheses can result in hundreds to thousands of duplicate references that should be removed before the screening process for efficiency. Research investigating the performance of automated methods for deduplicating references via reference managers a…

BACKGROUND: Breast cancer and its treatment can have many physical and psychological effects on affected women. Women's personal goals may provide insight into their priorities and motivations in the context of breast cancer. Incorporating personal goal-setting into support and care interventions may have an effect on…

INTRODUCTION: The global burden of conduct disorder is considerable, particularly in males. Deaths were followed by conflict and terrorism increased 143·3% from 2006 to 2016. The objective of this study is to provide a protocol of systematic review and meta-analysis to update the global prevalence of conduct disor…

I am writing this comment regarding the review article by Patsaki et al. titled "Benefits from Incorporating Virtual Reality in Pulmonary Rehabilitation of COPD Patients: A Systematic Review and Meta-Analysis" [...].

The purpose of the proposed review is, firstly, to map the core competencies for diabetes educators, as reported in the literature, and secondly, to review currently used criteria for core competencies in the assessment of diabetes educators.

The objective of this qualitative review is to synthesize the lived experiences of medication adherence among people with schizophrenia. The specific review question is: what are the experiences of taking prescribed medication among people with schizophrenia?

Introduction . The flipped classroom (FC) integrates online content delivery with in-class activities focused on knowledge application, such as discussions and problem-solving. While increasingly prevalent in medical education field, the efficacy of FC remains a subject of debate. Objective . This protocol outlines a s…

BACKGROUND: Geographic maldistribution of the health workforce remains a major challenge in Australia, with rural and remote communities experiencing persistent shortages that undermine access to and quality of care. Engagement in research is recognised as a potential mechanism for professional growth, continued learni…

INTRODUCTION: Tuberculosis (TB) is a notable public health issue in sub-Saharan Africa (SSA), disproportionately affecting vulnerable populations such as nomads. Their migratory lifestyles limit consistent access to TB diagnostic and treatment services, leading to delays in diagnosis and challenges in completing the fu…

OBJECTIVE: This project aims to gain a thoroughly understanding of the characteristics and experiences of psychological mistreatment among older adults, acknowledging the diversity within this population. It also seeks to identify clinical tools and practices for its detection and intervention. While there is extensive…

This systematic review protocol introduces the rationale to investigate how well the Vojta approach works to improve respiratory function and lessen neuromuscular deficits in premature newborns. Innovative approaches like the Vojta technique may offer a possible therapeutic path for preterm newborns, who frequently suf…

OBJECTIVE: The objective of this review will be to identify and map key components of transitional care programs for adult patients with stroke transitioning from the hospital (ie, acute care hospitals, acute rehabilitation facilities, skilled nursing facilities) to the community (ie, home environments, senior living,…

OBJECTIVE: This review aims to map existing evidence on the applications of large language models (LLMs) in perioperative care, including the types of technologies employed, the clinical tasks they support, and the evidence gaps that may influence their future adoption. INTRODUCTION: The perioperative period-encompass…

OBJECTIVE: The objective of this review is to identify and map the available evidence on interventions for heart failure dyads through telemedicine. INTRODUCTION: Heart failure is a chronic and progressive condition that requires significant lifestyle changes and daily support from informal caregivers. Due to the shar…