4,952,562 papers found

INTRODUCTION: The global burden of conduct disorder is considerable, particularly in males. Deaths were followed by conflict and terrorism increased 143·3% from 2006 to 2016. The objective of this study is to provide a protocol of systematic review and meta-analysis to update the global prevalence of conduct disor…

BACKGROUND: Medical imaging-based body composition analysis (BCA) has shown promise in offering detailed, noninvasive assessments of fat, muscle, and bone, but challenges persist in establishing consistent comparative standards. Current studies reveal significant variability in methodologies, which limits comparability…

BACKGROUND/OBJECTIVES: Prostate cancer is a major public health concern and a leading cause of cancer-related morbidity and mortality among men worldwide, with disproportionately high mortality rates in sub-Saharan Africa. Late diagnosis, limited access to screening services, low health-seeking behaviour, and sociocult…

BACKGROUND: Despite the many health benefits, global levels of physical activity remain insufficient. Traditional approaches to promoting physical activity have shown limited success, indicating the need for innovative strategies. Human-centred design thinking (HCDT) is a creative problem-solving and solution generatio…

INTRODUCTION: Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related death globally. Growing evidence links gut microbiota dysbiosis to CRC, with several reviews reporting consistent microbial alterations in CRC patients that may serve as non-invasive biomarkers. However,…

INTRODUCTION: Paediatric vulval lichen sclerosus (VLS) is a chronic disease with distressing symptoms and severe consequences when left untreated. Majority of existing data on pathophysiology and treatment is based on studies conducted among adult patients. Whereas the course of VLS, its symptomatology and prognosis ar…

BACKGROUND: The Liver is a vital organ in the human body, which plays a crucial role in various physiological processes. Oxidative stress is a critical factor in the pathogenesis and progression of various liver diseases, contributing to cellular damage and dysfunction. The Liver is particularly vulnerable to the harmf…

BACKGROUND: Self-medication is the practice of obtaining and using drugs without proper guidance or supervision. It can involve various behaviours that may harm individuals and society. Self-medication can cause serious health and economic problems for countries and healthcare systems. Therefore, current review aimed a…

Chrononutrition, which examines the relationship between circadian rhythms and nutrition, has been associated with glycemic outcomes in adults. However, published data on delayed meal timing, increased meal frequency and frequent breakfast skipping have shown inconsistent glycemic outcomes due to variations in methodol…

OBJECTIVE: This scoping review aims to comprehensively map the extent, range, and nature of studies that examine the various dimensions of nurses' sleep across all health care settings or countries. INTRODUCTION: Over the past 2 decades, the importance of sleep for nurses has gained increasing attention from health ca…

INTRODUCTION: Despite the evidence supporting the value of digital supports for enhancing youth mental health services, there is a lack of guidance on how best to engage with young people in coproduction processes during the design and evaluation of these technologies. User input is crucial in digital mental health, es…

INTRODUCTION: The HPV vaccine is characterized by its significant effectiveness in preventing the occurrence of cervical cancer. However, the South Asian countries face multiple challenges in implementing the human papillomavirus vaccine (HPV) at scale. Implementation of human papillomavirus vaccination for elimin…

INTRODUCTION: The care of children with cancer is a highly specialised field which requires well-educated, trained and dedicated nurses to provide high-quality care. In low/middle-income countries, the survival rate of children with cancer is low as compared with that of high-income countries due to the limited number…

INTRODUCTION: The COVID-19 pandemic posed a detrimental impact on the conduct of non-COVID-19 related clinical trials, raising concerns about the completeness of these studies and waste of resources. While several measures and strategies have been suggested to address these issues, a thorough and timely summarisation i…

INTRODUCTION: Hypertension affects 40%-60% of adults with hypertrophic cardiomyopathy (HCM), the most common inherited cardiac condition. It can be a diagnostic confounder for HCM, contributing to delayed diagnosis. Clinically, treatment of co-occurring hypertension and HCM poses challenges as first-line and second-lin…

OBJECTIVE: The objective of this systematic review is to apply COnsensus-based standards for the selection of health Measurement INstruments (COSMIN) methodology to review psychometric properties of patient-reported outcome measures (PROMs) of HIV-related stigma and/or discrimination. INTRODUCTION: Due to the developm…

BACKGROUND: The patient-centred medical home (PCMH) was conceived to address problems that primary care practices around the world are facing, particularly in managing the increasing numbers of patients with multiple chronic diseases. The problems include fragmentation, lack of access and poor coordination. The PCMH is…

OBJECTIVE: This scoping review aims to identify complex health interventions (CHI's) to prevent early childhood caries (ECC), explore the level of complexity of the identified CHI's, and explore the details of their development, evaluation, and implementation. INTRODUCTION: Many interventions to prevent ECC have multi…

INTRODUCTION: Pain is a common symptom in people with dementia; untreated, it reduces quality of life and causes suffering. People with dementia living in nursing homes most often have dementia in moderate to severe stages. The cognitive impairment, including language and communication difficulties, challenges pain ass…

OBJECTIVE: The objective of this review is to evaluate the effectiveness of psychosocial interventions on mental health outcomes in adult patients with Cardiovascular Diseases (CVDs) living in low- and middle-income countries (LMICs). INTRODUCTION: Mental health issues are highly prevalent among patients with CVDs lea…