4,998,788 papers found

A systematic review provides an overview of primary studies investigating a given research question, e.g., the effect of a certain treatment. Individual study results are sometimes synthesised in a meta-analysis. A critical reader should consider whether the systematic review is relevant and reliable, e.g., does it fol…

Digital health technologies (DHTs) have revolutionized clinical trials, offering unprecedented opportunities to streamline processes, enhance patient engagement, and improve data quality. Growing technology device and broadband access are contributing to the increasing number of DHT-enabled trials. Ideally, DHTs have t…

OBJECTIVE: The purpose of this review is to summarize the techniques used for network analysis of multimorbidity to inform development of a standard methodology. INTRODUCTION: There is a growing trend of using network analysis to investigate relationships between chronic illnesses in people with multimorbidities. Howe…

The objective of this review is to determine which 270-degree fundoplication procedure has a better outcome in patients with chronic or refractory gastroesophageal reflux disease (GERD). This review will identify the fundoplication approach for chronic or refractory GERD that provides better reflux control with minimal…

The objective of this scoping review is to investigate the outcomes measured and reported in trials of children with refractory epilepsy treated with ketogenic diet therapy. The scoping review will aim to list the outcomes and map the associated components including intervention (type of ketogenic diet therapy), defini…

The exponential growth of the systematic review methodology within health has been mirrored within medical education, allowing large numbers of publications on a topic to be synthesized to guide researchers and teachers. The robust, transparent and reproducible search methodologies employed offer scholarly rigor. The s…

BACKGROUND: Achilles tendinopathy is one of the most common overuse injuries in recreational and competitive runners, yet the clinical significance and frequency of abnormal sonographic characteristics in runners remains unclear. This paper presents a protocol for a systematic review which aims to assess existing liter…

High cost for systematic review of biomedical literature has generated interest in decreasing overall workload. This can be done by applying natural language processing techniques to 'automate' the classification of publications that are potentially relevant for a given question. Existing solutions need training using…

INTRODUCTION: Objective and accurate dietary monitoring is critical for comprehensive dietary assessment and improving nutritional health outcomes. The rapid advancement of wearable sensing technology presents a promising solution for effective dietary monitoring by reducing recall bias and enhancing user convenience,…

BACKGROUND: Cancer pain management is critical, especially at advanced stages. This is particularly important in Africa as most cancers are typically diagnosed at advanced stages. Given the central role of adequate pain management in advanced cancer care, this scoping review aims to examine the utilisation of patient-c…

OBJECTIVE: This review aims to identify and map the usage, application, and context of occupational justice concepts and related terms by occupational therapists and occupational scientists in relation to parents and children when children are born preterm or admitted to a neonatal intensive care unit. INTRODUCTION: O…

OBJECTIVE: The objective of this review is to synthesize qualitative evidence regarding the experiences of parents and prospective parents when receiving a diagnosis of Down syndrome for their child in the perinatal period. INTRODUCTION: Increased awareness of parental experiences when receiving a Down syndrome diagno…

OBJECTIVE: This scoping review will explore the literature related to occupational therapy interventions and delivery methods for pediatric complex regional pain syndrome. INTRODUCTION: Complex regional pain syndrome is a debilitating pain condition that is becoming increasingly diagnosed within the pediatric populati…

INTRODUCTION: Bipolar disorder (BD) is a severe mental health disorder that affects 2% of the adult population. Individuals with this disorder are at a higher risk for morbidity and functional difficulties. They may also experience significant challenges in their activities of daily living (ADLs). This systematic revie…

OBJECTIVE: The objective of this review is to synthesize the best available evidence regarding primary healthcare provider experiences of delivering nutrition-focused lifestyle modification interventions for adult patients with obesity or metabolic syndrome. INTRODUCTION: There is considerable evidence available regar…