11,450,267 papers found

This study's objective was to examine the autonomic control of heart rate and respiration during the neonatal period in human infants with prenatal exposure to cocaine. Four-hour daytime recordings of the electrocardiogram (ECG) were obtained from 15 cocaine-exposed and 13 non-exposed full-term neonates at 2 weeks of a…

The extraordinary genetic and behavioural diversity of dog breeds provides a unique opportunity for investigating the heritability of cognitive traits, such as problem-solving ability, social cognition, inhibitory control, and memory. Previous studies have mainly investigated cognitive differences between breed groups,…

OBJECTIVE: To estimate the effect of BMI on cause-specific hospital admissions and costs in men and women is not well understood, and this study's aim is to address this. METHODS: For 451,320 men and women aged 40 years or older recruited into the UK Biobank, followed up for 6 years on average, this study estimated an…

This study compared survival outcomes between neoadjuvant chemotherapy (NACT) and adjuvant chemotherapy (ACT) in patients with locally advanced, hormone receptor-positive, HER2-negative invasive lobular carcinoma (ILC). We conducted a retrospective cohort study using Surveillance, Epidemiology, and End Results (SEER) d…

BACKGROUND: This study explores the prevalence of subthreshold depression (SubD) and its association with factors in type 2 diabetes mellitus (T2DM) patients. METHODS: This cross-sectional study involved 808 outpatients with T2DM from ten hospitals in Beijing between September 2015 and January 2016. All participants c…

Breast cancer is the most common malignancy that affects women. MicroRNAs (miRNAs) play an essential role in cancer therapy and regulate many biological processes such as cisplatin resistance. The study's objective was to determine whether miR-182 dysregulation was the cause of cisplatin resistance in TNBC cell line MD…

Chemoresistance poses one of the most significant challenges of cancer therapy. Carboplatin (CbPt) is one of the most used chemotherapeutics in ovarian cancer (OVC) treatment. MRE11 constitutes a part of homologous recombination (HR), which is responsible for the repair of CbPt-induced DNA damage, particularly DNA cros…

Used for decades for biological warfare, Bacillus anthracis (category A agent) has proven to be highly stable and lethal. Quantitative risk assessment modeling requires descriptive statistics of the limit of detection to assist in defining the exposure. Furthermore, the sensitivities of various detection methods in env…

BACKGROUND: Health care workers (HCWs) presented frequent concerns regarding their health and their families' health and high levels of psychological distress during previous disease outbreaks, such as the SARS outbreak, which was associated with social isolation and intentional absenteeism. We aimed to assess HCWs con…

PURPOSE: Colorectal cancer (CRC) survivors are living longer; therefore, factors that improve outcomes, like symptom management and quality of life (QoL), have increasingly become important. This study examined CRC survivors' symptom(s) characteristics, positive psychology (benefit finding and post-traumatic growth), a…

The bicuspid aortic valve (BAV) is the most common congenital heart defect among adults, often leading to severe valve dysfunction and aortic complications. Despite its clinical significance, uncertainties persist regarding the impact of sports participation on the natural course of BAV disease. The SPREAD (Sport PRact…

BACKGROUND: Domestic violence against women (DVAW) is recognised globally as a violation of human rights and a public health concern. This study explores the relationship between DVAW and women's self-rated health status (SRHS). Identifying how DVAW drives women's SRHS could direct targeted interventions required to en…

Life history theory (LHT) predicts a trade-off between reproductive effort and the pace of biological aging. Energy invested in reproduction is not available for tissue maintenance, thus having more offspring is expected to lead to accelerated senescence. Studies conducted in a variety of non-human species are consiste…

BACKGROUND AND OBJECTIVES: Human papillomavirus (HPV) causes about 4.5% of all new human cancers. The purpose of this study was to look into the prevalence of various HPV types in patients with lung cancer. MATERIALS AND METHODS: The study included a cohort of 61 individuals who had received treatment at Imam Khomeini…

BACKGROUND: Physical activity has been widely recognized for its positive impact on mental health. Dance, as a form of physical activity, has garnered increasing attention in recent years. Existing literature suggests that dance specifically contributes to enhancing physical wellbeing and promoting emotional developmen…

Methods to assess environmental exposure to hazardous chemicals have primarily focused on quantification of individual chemicals, although chemicals often occur in mixtures, presenting challenges to the traditional risk characterization framework. Sampling sites in a defined geographic region provide an opportunity to…

INTRODUCTION: This study investigates Respectful Maternity Care (RMC) and its determinants in a rural area of Central India. RMC, which is crucial for reducing maternal mortality, emphasizes dignity, privacy, and autonomy during childbirth. The study aligns with the Sustainable Development Goals (SDG) to improve matern…

AIMS: We examined hypertriglyceridemic waist (HTGW) predictability for CVD and mortality. METHODS: Among Tehran Lipid and Glucose Study's participants aged ≥30 (n=8071), we selected those who participated in the follow-up study until 20-March-2009 (n=7154). After exclusions (320 missing data on waist circumfere…

INTRODUCTION: Unicompartmental knee arthroplasty (UKA) is one of the most effective surgical procedures for treating isolated medial compartment knee osteoarthritis. However, previous studies have regarded patellofemoral osteoarthritis as a contraindication for UKA. In contrast, most current research shows that damage…

Nature plays a crucial role in providing ecosystem services (ESs) essential for human wellbeing and biodiversity conservation in rural areas. However, existing paradigms often lack an integrative approach towards rural livelihoods and wellbeing, highlighting the need for a comprehensive understanding of the relationshi…