Radioligands for the study of the 5-HT transporter in vivo.
Brust P, Scheffel U, Szabo Z·IDrugs : the investigational drugs journal
Loss of 5-HT transporter (SERT) sites has been implicated in various neurodegenerative diseases and users of some amphetamine derivatives such as MDMA. Therefore, the development of suitable radioligands for neuroimaging of the SERT in the human brain is important. A large number of drugs have been labeled with 11C, 18…