2,645 papers found

OBJECTIVE: Primordial follicles in premature ovarian failure (POF) patients are very difficult to be activated spontaneously, so that mature oocytes are difficult to be obtained for in vitro fertilization. The aim of our review is to analyze and to systematize the published data regarding effectiveness of different str…

OBJECTIVE: Mobile health (mHealth) interventions show potential to broaden the reach of efficacious alcohol brief motivational interventions (BMIs). However, efficacy is mixed and may be limited by low participant attention and engagement. The present study examined the feasibility, acceptability, and preliminary effic…

BACKGROUND: Lately, radiomic studies featuring the development of a signature to use in prediction models in diagnosis or prognosis outcomes have been increasingly published. While the results are shown to be promising, these studies still have many pitfalls and limitations. One of the main issues of these studies is t…

OBJECTIVES: Current state-of-the-art natural language processing (NLP) techniques use transformer deep-learning architectures, which depend on large training datasets. We hypothesized that traditional NLP techniques may outperform transformers for smaller radiology report datasets. METHODS: We compared the performance…

BACKGROUND: Strokes are one of the leading causes of death worldwide. People with a lower socioeconomic position (SEP) (i.e. with regards to education, income and occupation) are at a higher risk of having a stroke and have worse clinical outcomes compared to the general population. Good knowledge levels about stroke r…

OBJECTIVE: To investigate whether application of a rigid dressing (RD) to the residual limb soon after transtibial amputation reduces the time from amputation to the first prosthetic casting/fitting compared with the residual limb managed with a soft dressing (SD). DATA SOURCES: Studies in humans were identified by a…

Cervical cancer is the third most common cancer in women worldwide. Persistent infection with an oncogenic human papillomavirus (HPV) is necessary, but not sufficient, for its development. Over many years, only a small proportion of women with chronic HPV infection progress to develop disease. The role of host genes an…

BACKGROUND: Systematic reviews depend on time-consuming extraction of data from the PDFs of underlying studies. To date, automation efforts have focused on extracting data from the text, and no approach has yet succeeded in fully automating ingestion of quantitative evidence. However, the majority of relevant data is g…

DNA methylation is important in regulation of gene expression and normal development because it alters the interplay between protein and DNA. Experiments have shown that a single 5-methylcytosine at different CpG sites (mCpG) might have different effects on specific recognition, but the atomistic origin and dynamic det…

OBJECTIVES: To synthesize current evidence on the clinical applications of generative artificial intelligence (GenAI), particularly large language models (LLMs), in head and neck oncology, with a focus on translational readiness, clinical safety, and real-world applicability. METHODS: A scoping review was conducted us…

The link between oral health and Alzheimer's disease (AD) has gained increasing attention in recent years. Emerging evidence suggests that this association is bidirectional, involving both biological mechanisms and behavioral consequences that reinforce one another over time.: A narrative synthesis of systematic review…

OBJECTIVE: This review systematically summarizes recent advances in plasma applications for dentin bonding, antibacterial enhancement, and implant surface modification. DATA: A systematic literature search was conducted across four electronic databases: Medline via PubMed, Cochrane Library, Wiley Online Library, and W…

OBJECTIVES: To elucidate factors related to the transitions of quality of life (QoL) and well-being in older adults living in residential facilities. DESIGN: We undertook a systematic review and narrative synthesis. SETTING AND PARTICIPANTS: The participants were individuals aged ≥60 years living in various ty…

In this manuscript, we present a novel mathematical model for understanding the dynamics of HIV/AIDS and analyzing optimal control strategies. To capture the disease dynamics, we propose a new Caputo-Fabrizio fractional-order mathematical model denoted as SEIEUPIATR, where the exposed class is subdivided into two categ…

OBJECTIVE: To report and synthesize the perspectives, experiences, and preferences of stroke survivors undertaking inpatient physical rehabilitation through a systematic review of qualitative studies. DATA SOURCES: MEDLINE, CINAHL, Embase, and PsycINFO were searched from database inception to February 2014. Reference…

OBJECTIVES/HYPOTHESIS: The purpose of this systematic review was to critically analyze infectious complications and treatment following transcartilaginous ear piercing. DATA SOURCES: MEDLINE Pubmed database. REVIEW METHODS: A MEDLINE PubMed database search using free text, including "ear chondritis," "ear perichondri…

BACKGROUND: Changes in the standard postmastectomy radiation therapy (PMRT) dosage schedule have led to the development of the hypofractionated radian therapy technique (HRT) that allows patients to receive fewer radian therapy sessions with higher doses in each session. Additionally, advancements in technology introdu…

BACKGROUND: Data addressing health-related quality of life (HRQOL) following maxillary reconstruction with free flaps remain scarce. Insight into these outcomes is essential for clinical decision-making. METHODS: A systematic review of Medline, Embase, Web of Science, Cochrane, and Google Scholar was performed for pub…

BACKGROUND: Most rare coding variants in monogenic disease genes remain classified as Variants of Uncertain Significance (VUS), limiting their use in clinical care. Many variant classifications have been submitted to ClinVar, often with rich free-text summaries of the evidence underlying each classification. These narr…

Vitamin E has been studied for its role in reducing the growth of colorectal cancer (CRC). CRC is a worldwide health concern. A meta-analysis reported that CRC patients have a lower concentration of serum vitamin E, suggesting it to be a risk factor. Although rodent models are widely used in disease research, their app…