11,452,220 papers found

The mandate for quality in all aspects of clinical practice, service delivery, and management practice has never been greater. The Institute of Medicine's (IOM) landmarkwork To Erris Human heightened the urgency of this serious issue. In a follow-up report, the IOM's Crossing the Quality Chasm called for radical change…

This study's purpose was to determine whether the influence of combined parental disorders can cause greater frequency in the occurrence of insecure child attachment and dysfunctions in self-regulation as opposed to the influence of one parent having a disorder. The research design is a quantitative meta-analysis that…

The good-enough processing account maintains that the human parser favours cognitively less effortful parsing (a heuristic stream) over deep and costly parsing (an algorithmic stream) in real-time processing. This study investigates how the two parsing routes work for sentence comprehension in Korean, an understudied l…

Research on positive emotions associated with the performance of an activity, such as work or study, has increased exponentially in recent years. Passion is understood as an attitude and intense emotion in the performance of an activity, and it has shown both positive and negative consequences for well-being. A link be…

This study's purpose was to establish the impact of a Career Advancement Program on critical thinking and clinical judgment of Registered Nurses. Findings of the study suggest that critical thinking and clinical judgment are not influenced by patterns of upward mobility. Additionally, an analysis did not indicate signi…

Brain involvement in myotonic dystrophy type 1 (DM1) is characterized by heterogeneous cognitive, behavioral, and affective symptoms and imaging alterations indicative of widespread grey and white matter involvement. The aim of the present study was to systematically review the literature on brain pathology in DM1. We…

To date, the scientific process for generating, interpreting, and applying knowledge has received less informatics attention than operational processes for conducting clinical studies. The activities of these scientific processes - the science of clinical research - are centered on the study protocol, which is the abst…

Human rights education has an encouraging effect on children's school routine. The aim of the present study was to investigate the effectiveness of a 12-session transformative human rights education intervention in improving children's school adjustment. Participants were 340 Greek primary school students assigned to i…

A properly formulated diet is an essential underpinning for all in vivo research. This chapter focuses on the use of diet in retinoid research from two perspectives: human research, in which diet is usually variable and analysis of dietary intake is paramount to interpreting the study's results, and animal (rodent) res…

The cell-based assay using yeast deletion mutants has been recognized as an efficient analysis to discover therapeutic compounds and reveal their mode of action. In this study, S. pombe deletion mutants-based HTS screening was carried out to identify potential anti-cancer agents. The NCI chemical library of 5700 compou…

Preliminary data [S. Burstein and S. A. Hunter, Biochem. Pharmac. 27, 1275 (1978)] showed that cannabinoids at levels of 1 microM or greater elevated the concentrations of prostaglandins in cell culture models. Further study [S. Burstein and S. A. Hunter, J. clin. Pharmac. 21, 240S (1981)] led to the suggestion that th…

Much biomedical research is observational. The reporting of such research is often inadequate, which hampers the assessment of its strengths and weaknesses and of a study's generalizability. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Initiative developed recommendations on what sh…

OBJECTIVE: To investigate if salivary nitrate correlates to the daily psychological stress and anxiety in a group of human subjects. METHODS: The convenient sample recruitment method was employed; data from seventy three subjects were analyzed. The Perceived Stress Scale (PSS) and Hamilton Anxiety Rating Scale (HAM-A)…

OBJECTIVE: Although previous research has established bidirectional links between many eating disorder (ED) symptoms and suicidal ideation (SI), no research has examined how symptoms of avoidant/restrictive food intake disorder (ARFID) longitudinally relate to SI, which is the current study's aim. METHODS: Iranian ado…

This study used an expanded technology acceptance framework that takes compliance and safety into account to investigate the uptake of Robotic Process Automation (RPA) in the transportation industry. To put this all-encompassing model to the test, we surveyed 190 people who work in the transportation industry. The resu…

This study's purpose was to test whether beta-adrenergic blockade reduces awareness of hypoglycemia. Six non-diabetic human adults received six experimental sessions each, one with each combination of intravenous propranolol (0.0, 0.05, and 0.15 mg/kg) followed by intravenous regular insulin (2 and 4 units). Physiologi…

OBJECTIVE: Infants' sleeping patterns can influence parents' sleep and their well-being. Infants' sleeping problems can evoke negative emotions from their parents because of the influence the problems have on parents' lives. However, little is known regarding the associations between infants' night sleep patterns and p…

The design of randomized controlled clinical studies can greatly benefit from iterative assessments of population representativeness of eligibility criteria. We propose a multi-trait metric - GIST 2.0 that can compute the a priori generalizability based on the population representativeness of a clinical study by explic…

The lesbian, gay, bisexual, transgender, and queer (LGBTQ) population deals with complex medical and behavioral issues coupled with barriers in accessing both healthcare and health insurance leading to poorer health outcomes as compared with the general population. Because this community is often overlooked in efforts…

This study has focused on studying Chinese medical history for the past 10 years (2010-2019). There has been no overall introduction to how the study of Chinese medical history has been carried out so far in Korea. To understand the trend for the recent 10 years, understanding of the period before that is needed. This…