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Prevalence of respiratory complications in long-term survivors of childhood and adolescent cancer: a systematic review and meta-analysis.
Liu Jiayuan, You Xiangying, Huang Yuyao·Translational pediatrics
BACKGROUND: Improved survival after childhood and adolescent cancer has led to a growing population of long-term survivors, yet the burden of late respiratory complications remains poorly quantified. In this study, the prevalence of respiratory complications in long-term survivors was quantified, and associated risk fa…
Pharmacotherapy for Children and Adolescents With Overweight or Obesity: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.
Luo Li, Huang Tingting, Yan Zijing, +10 more·Diabetes, obesity & metabolism
AIMS: The escalating global prevalence of childhood and adolescent overweight and obesity constitutes a pressing public health issue. This network meta-analysis aimed to compare the efficacy and safety of pharmacologic interventions as adjuncts to lifestyle therapy in this population.
MATERIALS AND METHODS: Randomized…
Effect of Antihypertensive Drug Classes on Stroke Prevention: A Systematic Review and Meta-Analysis.
Shams Zobair Ibn, Jahan Maya Kazi Iffat, Bin Shahid Syed Tasin, +6 more·Cureus
Hypertension is the most common modifiable risk factor for stroke. However, whether different classes of antihypertensive drugs provide equal protection against stroke remains controversial. This review aimed to systematically compare the effects of various antihypertensive drug classes on stroke prevention through a c…
Efficacy of Botulinum Toxin Injections for Erectile Dysfunction and Premature Ejaculation: A Meta-Analysis of Randomized Controlled Trials.
Saadawi Badr, Alghamdi Abdulmajeed, Ismail Alaa Abdulrahman, +4 more·Current drug research reviews
BACKGROUND: Male sexual dysfunction, with specific reference to erectile malfunction and premature ejaculation, interferes with both physical and social health of individuals. Erectile dysfunction is seen as the inability to obtain a construction that is rigid enough for successful sexual intercourse, while premature e…
Necrotizing (abscessing) lymphadenopathy is a clinically relevant condition with a broad differential diagnosis, including acute bacterial infections, mycobacterial disease, zoonoses, fungal and parasitic infections, autoimmune disorders, and malignancies with central necrosis. Early and reliable differentiation betwee…
Perioperative Nicotine for Postoperative Pain and Nausea: A Systematic Review with Clinical and Methodological Insights.
Almogbel Feras Twfeq, Alghamdi Mohammed Ali, Elkarouri Ali Mohamed, +9 more·Anesthesiology and pain medicine
CONTEXT: Nicotine has been investigated in prior studies for its analgesic effects and its impact on postoperative nausea and vomiting (PONV), yet results have been inconsistent.
OBJECTIVES: This systematic review and narrative synthesis evaluates the effects of perioperative nicotine administration on postoperative p…
Ocular Comorbidities of Psoriasis: A Systematic Review and Meta-analysis of Observational Studies.
Wang Ching-Ya, Lin Tzu-Yi, Wang Tzu-Yu, +1 more·American journal of ophthalmology
TOPIC: Ocular comorbidities of psoriasis: A systematic review and meta-analysis of observational studies.
DESIGN: Systematic review and meta-analysis.
CLINICAL RELEVANCE: Ocular comorbidities of psoriasis have been raised with growing evidence. Certain eye diseases require prompt diagnosis and appropriate interventio…
BACKGROUND: Brainstem cavernous malformations (BSCMs) are rare yet high-risk vascular lesions with a complex clinical course due to their eloquent location. Optimal treatment remains a topic of debate. This review aims to evaluate the outcomes of different management strategies for BSCMs, with a focus on rebleeding, fu…
Outcomes of Antithrombotic Therapy in Patients Undergoing Gastrointestinal Surgery: A Meta-Analysis.
Tariq Faryal, Ali Hasnain, Baig Abdul Moeed, +5 more·Cureus
Antithrombotic therapy is commonly prescribed for the prevention and management of thromboembolic diseases but poses significant challenges in the perioperative setting of gastrointestinal (GI) surgery due to the competing risks of bleeding and thrombosis. This meta-analysis aimed to evaluate the clinical outcomes asso…
Effectiveness of acupuncture for post-stroke aphasia: protocol for a systematic review and meta-analysis.
Jia Junzhe, Shan Yuanli, Tang Yihe, +1 more·Frontiers in neurology
BACKGROUND: Post-stroke aphasia (PSA) is a prevalent and debilitating consequence of stroke, significantly impairing communication abilities and reducing patients' quality of life. While speech and language therapy represents standard care, many patients experience incomplete recovery. Acupuncture, a key component of t…
The impact of system performance improvement on patients with cardiac arrest: An updated systematic review.
Ko Ying-Chih, Lee Tse-Ying, Hsieh Ming-Ju, +5 more·The American journal of emergency medicine
AIM: To investigate the effect of system-level interventions designed to enhance outcomes for cardiac arrest patients.
METHOD: We searched PubMed, Ovid EMBASE, and the Cochrane Central Register of Controlled Trials (CENTRAL) databases to identify publication from July 2020 to December 2024. Two independent reviewers p…
The effect of low-carbohydrate diets, based on changes in intake of dietary saturated fats on circulating TNF-α and interleukin- 6 levels in adults: a systematic review and meta-analysis of randomized controlled trials.
BACKGROUND: Low-carbohydrate diets (LCDs) have been associated with inflammation while there is still conflicting evidence regarding the effects of this type of diet on inflammatory markers and the clinical benefit of them remains uncertain. So, we aimed to ascertain the effects of LCDs on serum concentrations of tumor…
A network meta-analysis of the comparative efficacy of different dietary approaches on glycaemic control and weight loss in patients with type 2 diabetes mellitus and overweight or obesity.
Yuan Yahui, Chen Chun, Liu Qiaoyun, +5 more·Food & function
: Despite considerable literature supporting the benefit of dietary interventions in individuals with type 2 diabetes mellitus (T2DM) and overweight/obesity, which diet works best is currently unknown. We conducted a systematic review and network meta-analysis (NMA) to evaluate the comparative effectiveness of differen…
Heart rate variability in acute pancreatitis: a narrative review.
Liau Matthias Yi Quan, Liau Jovan Yi Jun, Selvakumar Surya Varma, +2 more·Translational gastroenterology and hepatology
BACKGROUND AND OBJECTIVE: Acute pancreatitis (AP) is a complex inflammatory disorder with potential systemic repercussions including sepsis, multiple organ failure and mortality. As such, the development of a prognostic tool to assess the complications and severity of AP is critical as urgent medical intervention is wa…
The effectiveness of extended reality on relieving pain after total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials.
Su Shilong, Wang Ruideng, Chen Zhengyang, +2 more·Archives of orthopaedic and trauma surgery
PURPOSE: Patients with total knee arthroplasty (TKA) often suffer from severe postoperative pain, which seriously hinders postoperative rehabilitation. Extended reality (XR), including virtual reality, augmented reality, and mixed reality, has been increasingly used to relieve pain after TKA. The purpose of this study…
BACKGROUND: A rare gene variant in SCN5A can be found in approximately 20%-25% of patients with Brugada syndrome (BrS).
OBJECTIVE: The aim of this systematic review and meta-analysis was to evaluate the differences in clinical characteristics of BrS patients with and without SCN5A rare variants and the prognostic role…
BACKGROUND: Research comparing the effectiveness of central aortic cannulation to axillary artery cannulation in repairing acute type A aortic dissection is limited and controversial. This meta-analysis aimed to compare early outcomes of central aortic cannulation versus axillary artery cannulation for surgery for acut…
PURPOSE: Myopia is controlled optically with peripheral defocus spectacles, multifocal contact lenses, or orthokeratology lenses. However, it is unknown which optical correction will improve visual performance. This scoping review aimed to identify and summarize studies on various visual functions using optical correct…
Can inspiratory muscle training benefit patients with COVID-19? A systematic review and meta-analysis.
Chen Yusha, Liu Xuefeng, Tong Zhaohui·Journal of medical virology
The possible benefits of inspiratory muscle training (IMT) on mechanical and clinical outcomes in patients with Coronavirus disease-2019 (COVID-19) remain controversial. We conducted a meta-analysis to evaluate the effect of IMT in the rehabilitation strategy of patients with COVID-19. The Pubmed, Embase, Web of Scienc…