Reaching soldiers with untreated substance use disorder: lessons learned in the development of a marketing campaign for the Warrior Check-Up study.
Walton Thomas O, Walker Denise D, Kaysen Debra L, +3 more·Substance use & misuse
The Warrior Check-Up, a confidential telephone-delivered intervention, is designed to reach active-duty soldiers with untreated substance-use disorder at a large U.S. military base. This paper describes the development and successful implementation of the study's marketing strategies at the recruitment period's midpoin…
Perception and action de-coupling in congenital amusia: sensitivity to task demands.
Williamson Victoria J, Liu Fang, Peryer Guy, +2 more·Neuropsychologia
Theories that purport the existence of a distinct auditory action stream have received support from the finding that individuals with congenital amusia, a disorder of pitch perception, are able to reproduce the direction of a pitch change that they are unable to identify (Loui, Guenther, Mathys, & Schlaug, 2008). Altho…
Barriers to adopting genomics into public health education: a mixed methods study.
Chen Lei-Shih, Goodson Patricia·Genetics in medicine : official journal of the American College of Medical Genetics
PURPOSE: To examine public health educators' perceptions of barriers to incorporate genomic content (information, discoveries, technologies) into health promotion.
METHODS: Mixed methods (qualitative and quantitative approaches)-using a fully mixed sequential dominant status design-were employed. Qualitative data were…
Supporting siblings through the pediatric bone marrow transplant trajectory: perspectives of siblings of bone marrow transplant recipients.
Wilkins Krista Lynn, Woodgate Roberta Lynn·Cancer nursing
When a child undergoes bone marrow transplant (BMT), the entire family is affected by the demands of the transitions encountered throughout the BMT experience. Although there is a growing body of knowledge on how healthy siblings adjust to the BMT experience, there is still much to be learned. Part of a larger study ai…
Use of a radial artery compression device for noninvasive, near-continuous blood pressure monitoring in the ED.
Thomas Stephen H, Winsor Greg R, Pang Peter S, +2 more·The American journal of emergency medicine
This study's goal was to test a novel device using continuous partial radial artery compression for mean arterial pressure (MAP) measurement. A prospective, nonblind, convenience-sample trial at a level I center (annual ED census 70,000) enrolled 15 adults with indwelling radial arterial catheters and accessible contra…
Clinical quality measurement. Comparing chart review and automated methodologies.
Dresser M V, Feingold L, Rosenkranz S L, +1 more·Medical care
OBJECTIVES: This study investigates the use of data from automated systems within a large managed care plan to create indicators of clinical quality.
METHODS: Measures from the first year of Health Plan Employer Data and Information Set, HEDIS 2.0, are used to compare chart review and automated analysis methodologies.…
[A study on the depression level of pregnant women and puerpera].
Kang J H·Taehan kanho. The Korean nurse
The samples of this study were 100 pregnant women that visited for antenatal care Chunchon Songshim Hospital and Chunchon Provincial Hospital (Maternal Child Health) and 100 puerpera that were admitted for childbirth to those hospitals August 1 through 31, 1989. The writer is interested in the depression level of pregn…
Application of mixed-methods design in community-engaged research: Lessons learned from an evidence-based intervention for Latinos with chronic illness and minor depression.
Aguado Loi Claudia X, Alfonso Moya L, Chan Isabella, +4 more·Evaluation and program planning
The purpose of this paper is to share lessons learned from a collaborative, community-informed mixed-methods approach to adapting an evidence-based intervention to meet the needs of Latinos with chronic disease and minor depression and their family members. Mixed-methods informed by community-based participatory resear…
Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans.
OBJECTIVE: Long-chain fatty acids (LCFAs) contribute to metabolic homeostasis in part via gene regulation. This study's objective was to identify novel LCFA target genes in human skeletal muscle cells (myotubes).
RESEARCH DESIGN AND METHODS: In vitro methods included culture and treatment of human myotubes and C2C12 c…
Isolation and characterisation of human gingival margin-derived STRO-1/MACS(+) and MACS(-) cell populations.
El-Sayed Karim M Fawzy, Paris Sebastian, Graetz Christian, +5 more·International journal of oral science
Recently, gingival margin-derived stem/progenitor cells isolated via STRO-1/magnetic activated cell sorting (MACS) showed remarkable periodontal regenerative potential in vivo. As a second-stage investigation, the present study's aim was to perform in vitro characterisation and comparison of the stem/progenitor cell ch…
OBJECTIVES: A biomechanical study was performed to test the hypothesis that a varus deformity of the humeral head decreases supraspinatus (SSP) efficiency and increases deltoid elevation forces in human specimens.
METHODS: Twenty-four fresh-frozen human shoulder specimens were prepared by preserving the rotator cuff a…
Evidences of dual role of vitamin D through cellular energy homeostasis and inflammation pathway in risk of cancer in obese subjects.
Hossein-Nezhad A, Mirzaei K, Keshavarz S A, +3 more·Minerva medica
AIM: The underlying molecular mechanisms of the role obesity plays in increasing the risk of cancer are not well illuminated. Several mechanisms are proposed for vitamin D as an anti-cancer agent in various malignancies which may be attributed to both its both its anti-inflammatory characteristics as well as its mediat…
Hospital-based violence intervention programs: An analysis of costs and key components.
O'Toole Megan J, Schnippel Kathryn, Larson Bruce·The journal of trauma and acute care surgery
BACKGROUND: Firearm assaults contribute to nearly 18,000 deaths and at least twice as many injuries annually, with immense human and financial costs. Gun violence survivors especially face unique and long-term physical, mental, economic, and safety-related challenges. Hospital-based violence intervention programs (HVIP…
A role for muscarinic receptors in neutrophil extracellular trap formation and levamisole-induced autoimmunity.
Carmona-Rivera Carmelo, Purmalek Monica M, Moore Erica, +8 more·JCI insight
Levamisole, an anthelmintic drug with cholinergic properties, has been implicated in cases of drug-induced vasculitis when added to cocaine for profit purposes. Neutrophil extracellular trap (NET) formation is a cell death mechanism characterized by extrusion of chromatin decorated with granule proteins. Aberrant NET f…
PMID28194438
DOI10.1172/jci.insight.89780
PMCIDPMC5291726
PublisherAmerican Society for Clinical Investigation
Expression of activation markers on basophils in a controlled model of anaphylaxis.
Gober Laura M, Eckman John A, Sterba Patricia M, +4 more·The Journal of allergy and clinical immunology
BACKGROUND: Anaphylaxis has variable clinical presentations and lacks reliable biomarkers. Expression of activation markers on basophils has been useful in assessing sensitization in IgE-mediated diseases but has not been examined in vivo in anaphylaxis.
OBJECTIVE: The study's goals were to assess the baseline express…
Mothers' and fathers' attitudes toward stuttering in the Middle East compared to Europe and North America.
Hughes Stephanie, Junuzovic-Zunic Lejla, Mostafa Eman, +7 more·International journal of language & communication disorders
BACKGROUND: Parents play a central role in the treatment of childhood stuttering. Addressing parental attitudes toward stuttering is helpful therapeutically. The extent to which differences in attitudes toward stuttering exist on the basis of sex, geographical region and parental status (e.g., parent of a stuttering ch…
Assessment of healthcare measures, healthcare resource use, and cost of care among severe hemophilia A patients in Mumbai region of India.
Jadhav U, Mukherjee K·Journal of postgraduate medicine
BACKGROUND: In India, the low public health priority given to rare disorders such as hemophilia hinders their management and optimal care, leading to relatively poor health outcomes. This study aims to profile the multidimensional health status of patients with severe hemophilia A, and its association with the use of h…
Associations among patient characteristics, health-related quality of life, and spiritual well-being among Arab Muslim cancer patients.
Lazenby Mark, Khatib Jamal·Journal of palliative medicine
BACKGROUND: Despite Islam being the world's second largest religion and despite the fact that there are 22 Arabic-speaking nations representing North Africa and the Middle East, little is known about the relationship between spiritual well-being and health-related quality of life (HrQoL) for Arabic-speaking Muslims in…
Neurocognitive functions in patients with hepatitis C infection.
Horváth Gergely, Keleti Teodóra, Makara Mihály, +2 more·Ideggyogyaszati szemle
BACKGROUND AND PURPOSE: With improving treatment options, more attention is being paid to the neurocognitive symptoms related to hepatitis C infection (HCI). While HCI-related neurocognitive impairments are frequently subclinical, they can influence patients' quality of life and fitness to work. Objective - The aim of…