2,530 papers found

Total forearm free flap procedures after forequarter amputations have been sparsely described in the literature. Using the amputated arm as a "free filet flap" remains a viable surgical option after radical forequarter amputations performed for the resection of large, invasive tumors of the shoulder or thoracic wall re…

PURPOSE: To create a systematic overview of the available reconstructive techniques, facial nerve grading scales, physical evaluation, the reversibility of paralysis, non-reconstructive procedures and medical therapy, physical therapy, the psychological aspect of facial paralysis, and the prevention of facial nerve inj…

BACKGROUND: Microstomia is characterized by a reduced oral aperture, leading to impairments in speech, feeding, dental hygiene, and facial expressions. Nonsurgical treatments offer limited benefits for mild cases although surgical interventions have been shown to yield better outcomes. However, the unique anatomical ch…

OBJECTIVE: Primordial follicles in premature ovarian failure (POF) patients are very difficult to be activated spontaneously, so that mature oocytes are difficult to be obtained for in vitro fertilization. The aim of our review is to analyze and to systematize the published data regarding effectiveness of different str…

IMPORTANCE: Large language models (LLMs) possess a range of capabilities which may be applied to the clinical domain, including text summarization. As ambient artificial intelligence scribes and other LLM-based tools begin to be deployed within healthcare settings, rigorous evaluations of the accuracy of these technolo…

BACKGROUND: Systematic reviews depend on time-consuming extraction of data from the PDFs of underlying studies. To date, automation efforts have focused on extracting data from the text, and no approach has yet succeeded in fully automating ingestion of quantitative evidence. However, the majority of relevant data is g…

DNA methylation is important in regulation of gene expression and normal development because it alters the interplay between protein and DNA. Experiments have shown that a single 5-methylcytosine at different CpG sites (mCpG) might have different effects on specific recognition, but the atomistic origin and dynamic det…

BACKGROUND: Changes in the standard postmastectomy radiation therapy (PMRT) dosage schedule have led to the development of the hypofractionated radian therapy technique (HRT) that allows patients to receive fewer radian therapy sessions with higher doses in each session. Additionally, advancements in technology introdu…

BACKGROUND: Lately, radiomic studies featuring the development of a signature to use in prediction models in diagnosis or prognosis outcomes have been increasingly published. While the results are shown to be promising, these studies still have many pitfalls and limitations. One of the main issues of these studies is t…

OBJECTIVES: Current state-of-the-art natural language processing (NLP) techniques use transformer deep-learning architectures, which depend on large training datasets. We hypothesized that traditional NLP techniques may outperform transformers for smaller radiology report datasets. METHODS: We compared the performance…

Breastfeeding has been associated to an improved mother-child bond, although this link is lacking the sufficient empirical support.The aims of this study were to carry out a systematic review as a continuation to the one by Jansen et al., and to clarify the link between breastfeeding and mother-infant relationships.Dat…

Cervical cancer is the third most common cancer in women worldwide. Persistent infection with an oncogenic human papillomavirus (HPV) is necessary, but not sufficient, for its development. Over many years, only a small proportion of women with chronic HPV infection progress to develop disease. The role of host genes an…

OBJECTIVES: To synthesize current evidence on the clinical applications of generative artificial intelligence (GenAI), particularly large language models (LLMs), in head and neck oncology, with a focus on translational readiness, clinical safety, and real-world applicability. METHODS: A scoping review was conducted us…

The link between oral health and Alzheimer's disease (AD) has gained increasing attention in recent years. Emerging evidence suggests that this association is bidirectional, involving both biological mechanisms and behavioral consequences that reinforce one another over time.: A narrative synthesis of systematic review…

OBJECTIVES: To elucidate factors related to the transitions of quality of life (QoL) and well-being in older adults living in residential facilities. DESIGN: We undertook a systematic review and narrative synthesis. SETTING AND PARTICIPANTS: The participants were individuals aged ≥60 years living in various ty…

In this manuscript, we present a novel mathematical model for understanding the dynamics of HIV/AIDS and analyzing optimal control strategies. To capture the disease dynamics, we propose a new Caputo-Fabrizio fractional-order mathematical model denoted as SEIEUPIATR, where the exposed class is subdivided into two categ…

INTRODUCTION: Task-shifting from primary care physicians (PCPs) to nurses is one option to better and more efficiently meet the needs of the population in primary care and to overcome PCP shortages. This protocol outlines an overview of systematic reviews to assess the effects of delegation or substitution by nurses of…

OBJECTIVES: This review aimed to critically appraise the evidence for biomarkers in blood serum, gingival crevicular fluid (GCF), saliva, and urine in comparison with standard radiographic indices for skeletal maturation assessment. MATERIALS AND METHODS: A thorough literature search in multiple databases was conducte…

OBJECTIVE: To report and synthesize the perspectives, experiences, and preferences of stroke survivors undertaking inpatient physical rehabilitation through a systematic review of qualitative studies. DATA SOURCES: MEDLINE, CINAHL, Embase, and PsycINFO were searched from database inception to February 2014. Reference…

BACKGROUND: Data addressing health-related quality of life (HRQOL) following maxillary reconstruction with free flaps remain scarce. Insight into these outcomes is essential for clinical decision-making. METHODS: A systematic review of Medline, Embase, Web of Science, Cochrane, and Google Scholar was performed for pub…