2,699 papers found

BACKGROUND: Fusobacteriae are facultative anaerobic gram-negative bacilli which cause a range of invasive infections, amongst which pyogenic liver abscesses are rare. We describe a case of Fusobacterium nucleatum liver abscess and review the relevant literature. CASE PRESENTATION: A 51-year-old lady presented with a 4…

Reactive arthritis (ReA) is an inflammatory spondyloarthritis occurring after infection at a distant site. Chlamydia trachomatis is proposed to be the most common cause of ReA, yet the incidence of sexually acquired ReA (SARA) has not been well established. We therefore carried out a systematic literature review to col…

AIMS: To assess the prevalence of burnout among emergency ambulance service workers in one ambulance station; to determine if there are any variances based on socio-demographic information such as gender, clinical grade and length of service; to examine the distinctions between personal, work-related and patient-relate…

BACKGROUND: Complete tumour response (pCR) to neo-adjuvant chemo-radiotherapy for rectal cancer is associated with a reduction in local recurrence and improved disease-free and overall survival, but is achieved in only 20-30% of patients. Drug repurposing for anti-cancer treatments is gaining momentum, but the potentia…

BACKGROUND: Many previous studies have investigated the prognostic value of body mass index (BMI) for GBM outcomes with varying results. We present a comprehensive literature review and meta-analysis investigating BMI as a prognostic value in GBM. METHODS: A systematic review of literature on adult patients with GBM p…

AIM: To describe Irish Healthcare Assistants'/carers' (HCAs) working conditions and wellbeing during COVID-19 Wave 1 and examine associations between PPE access and infection-related outcomes. METHODS: A 24-hour rapid-response, mixed-method survey (23/04/2020) of HCAs/carers in Ireland (456) across care settings. Quan…

Sickle cell anemia is a hemoglobinopathy that causes complications such as Vaso-Occlusive Crisis (VOC), stroke, priapism, Acute Chest Syndromes (ACS), and bone infarcts due to blood vessel occlusion, resulting in hypoxia, ischemia, and inflammation. Preventing these incidents improves the quality of life and lowers mor…

CONTEXT: In the UK, supervised learning events (SLE) replaced traditional workplace-based assessments for foundation-year trainees in 2012. A key element of SLEs was to incorporate trainee reflection and assessor feedback in order to drive learning and identify training issues early. Few studies, however, have investig…

UNLABELLED: SciMiner is a web-based literature mining and functional analysis tool that identifies genes and proteins using a context specific analysis of MEDLINE abstracts and full texts. SciMiner accepts a free text query (PubMed Entrez search) or a list of PubMed identifiers as input. SciMiner uses both regular expr…

PURPOSE: To create a systematic overview of the available reconstructive techniques, facial nerve grading scales, physical evaluation, the reversibility of paralysis, non-reconstructive procedures and medical therapy, physical therapy, the psychological aspect of facial paralysis, and the prevention of facial nerve inj…

Total forearm free flap procedures after forequarter amputations have been sparsely described in the literature. Using the amputated arm as a "free filet flap" remains a viable surgical option after radical forequarter amputations performed for the resection of large, invasive tumors of the shoulder or thoracic wall re…

BACKGROUND: Microstomia is characterized by a reduced oral aperture, leading to impairments in speech, feeding, dental hygiene, and facial expressions. Nonsurgical treatments offer limited benefits for mild cases although surgical interventions have been shown to yield better outcomes. However, the unique anatomical ch…

OBJECTIVE: Primordial follicles in premature ovarian failure (POF) patients are very difficult to be activated spontaneously, so that mature oocytes are difficult to be obtained for in vitro fertilization. The aim of our review is to analyze and to systematize the published data regarding effectiveness of different str…

OBJECTIVE: To synthesize the international evidence on the impact of clean intermittent catheterization on quality of life and resource utilization in patients with spinal cord injury and urological complications, to support a review of policies that shift the financial burden of catheterization to families in Chile.…

Psychogenic erectile dysfunction (ED) is a distinct clinical condition characterized by predominant psychological or relational factors. Despite its prevalence, diagnostic criteria remain heterogeneous and are often based on exclusion of organic causes. Current guidelines recommend cognitive behavioral therapy (CBT), e…

OBJECTIVES: To synthesize current evidence on the clinical applications of generative artificial intelligence (GenAI), particularly large language models (LLMs), in head and neck oncology, with a focus on translational readiness, clinical safety, and real-world applicability. METHODS: A scoping review was conducted us…

The link between oral health and Alzheimer's disease (AD) has gained increasing attention in recent years. Emerging evidence suggests that this association is bidirectional, involving both biological mechanisms and behavioral consequences that reinforce one another over time.: A narrative synthesis of systematic review…

OBJECTIVE: This review systematically summarizes recent advances in plasma applications for dentin bonding, antibacterial enhancement, and implant surface modification. DATA: A systematic literature search was conducted across four electronic databases: Medline via PubMed, Cochrane Library, Wiley Online Library, and W…

OBJECTIVES: To elucidate factors related to the transitions of quality of life (QoL) and well-being in older adults living in residential facilities. DESIGN: We undertook a systematic review and narrative synthesis. SETTING AND PARTICIPANTS: The participants were individuals aged ≥60 years living in various ty…

In this manuscript, we present a novel mathematical model for understanding the dynamics of HIV/AIDS and analyzing optimal control strategies. To capture the disease dynamics, we propose a new Caputo-Fabrizio fractional-order mathematical model denoted as SEIEUPIATR, where the exposed class is subdivided into two categ…