5,082,196 papers found

E-cigarettes are often marketed as a safer alternative to combustible cigarettes. However, their health effects, especially those associated with long-term use, remain largely uncertain. We conducted an umbrella review of the cardiopulmonary and carcinogenic risks of e-cigarette use, distinguishing between short-term a…

C-reactive protein (CRP) has been studied extensively for association with a large number of non-infectious diseases and outcomes. We aimed to evaluate the breadth and validity of associations between CRP and non-infectious, chronic health outcomes and biomarkers. We conducted an umbrella review of systematic reviews a…

BACKGROUND: Within systematic reviews, when searching for relevant references, it is advisable to use multiple databases. However, searching databases is laborious and time-consuming, as syntax of search strategies are database specific. We aimed to determine the optimal combination of databases needed to conduct effic…

Writing for publication is an important way to contribute to the knowledge base for professional nurses. This paper reviews the process of writing a professional paper from identification of a topic to the time the paper appears in print. Web-based resources to facilitate the writing process are highlighted.

BACKGROUND: There is considerable interest in the effectiveness of financial incentives in the delivery of health care. Incentives may be used in an attempt to increase the use of evidence-based treatments among healthcare professionals or to stimulate health professionals to change their clinical behaviour with respec…

PURPOSE: This study aims to synthesize existing evidence on the effectiveness of nonpharmacological interventions designed to increase the intrinsic capacity (IC) of community-dwelling older adults. METHODS: An umbrella review of systematic reviews from 2015 to October 31, 2024, with no language restrictions, was cond…

BACKGROUND: Synthesizing what is known about the environmental drivers of health is instrumental to taking prevention-oriented action. Methods of research synthesis commonly used in environmental health lag behind systematic review methods developed in the clinical sciences over the past 20 years. OBJECTIVES: We sough…

The overall goal of a systematic review or meta-analysis is to combine results of previous studies to arrive at summary conclusions about a body of research. In radiology, systematic reviews or meta-analyses can be used to calculate a summary estimate of effect size of a treatment that used imaging data to assess outco…

Diabetes-related foot complications, defined in this review as diabetic foot ulceration and diabetes-related lower-extremity amputation, remain among the most disabling and costly consequences of diabetes. Evidence on their associated factors is dispersed across multiple systematic reviews and meta-analyses. This umbre…

OBJECTIVES: The primary objectives of this umbrella review were to (a) quantify the relative importance, of "severity" and "rarity" criteria in health resource allocation; and (b) analyze the contextual factors influencing the relative importance. The secondary objective was to examine how "severity" and "rarity" crite…

INTRODUCTION: Systematic Review and Meta-Analysis (SRMAs) in neurosurgery have significantly increased. With approximately 1 million patients affected by cerebrovascular disease annually, interpreting SRMAs necessitates a systematic approach. The objective of this review is to identify and describe four essential…

Sedentary behaviour research is rapidly growing. Scoping reviews are important to inform policy and practice.The aim of this scoping a review was to map the available evidence from systematic reviews and meta-analyses of sedentary behaviour research on adults (≥18 years), within the phases of the behavioura…

Specific spinal postures and physical activities have been linked to low back pain (LBP) but previous reviews have produced contrasting outcomes. This umbrella review examined (1) what relationship, if any, is evident between specific spinal postures or physical activities and LBP; (2) the quality of existing systemati…

OBJECTIVE: To identify which exercise combinations are most effective as part of a lower extremity injury prevention programme for team-sport athletes. DESIGN: Umbrella review. DATA SOURCES: A comprehensive literature search was performed in PubMed, Scopus, Cochrane Library and PEDro databases. Studies published betw…

BACKGROUND: The use of definitive abutments (DAs) at time of implant placement has been introduced to overcome limitations of dis/reconnection of healing/provisional abutments (PAs). With little and inconsistent information in the literature regarding the effectiveness of using DAs, the aim of this systematic review is…

OBJECTIVES: This study aimed to conduct a methodological assessment of paper-based systematic reviews (SR) published in oral health using a validated checklist. A secondary objective was to explore temporal trends on methodological quality. MATERIAL AND METHODS: Two electronic databases (OVID Medline and OVID EMBASE)…

Much animal research into potential treatments for humans is wasted because it is poorly conducted and not evaluated through systematic reviews