376,100 papers found

Clinical studies on intracoronary bone marrow cell (BMCs) infusion in patients with acute myocardial infarction (AMI) revealed mixed results. Recently, meta-analysis on this topic have been conducted and found that there was marked heterogeneity between trials. The objective of this systematic review is to have a retro…

BACKGROUND: The purpose of this study is to identify a first choice Root-end Filling Material (RFM) as regards the apical sealing ability. METHODS: The method we have used is the so called Metanalysis. It consists of the selection of all experimental studies already existing in literature and of the statistical proces…

Fifteen case-control studies on the relationship between smoking and lung cancers in China were analyzed and evaluated by the method of meta-analysis, using both the fixed-effect and the random-effect models. The cumulative cases and controls were 5703 and 5669, respectively. Calculations based on the fixed-effect mode…

OBJECTIVE: To review published clinical trials comparing the efficacy of trazodone with that of tricyclic antidepressant medication. DATA SOURCES: MEDLINE was searched for relevant articles published from 1983 to 1991. The bibliography of a review article was searched for further references. STUDY SELECTION: In all,…

Seven randomized studies during the past 5 years have evaluated or are evaluating the efficacy of warfarin or aspirin or both in decreasing the risk of embolic events in patients with nonrheumatic atrial fibrillation. By March 1990, two of the studies had been published, both of which showed a statistically significant…

To assess the effect of selective decontamination of the digestive tract on respiratory tract infections and survival of patients treated in an intensive care unit, we carried out a meta-analysis of clinical studies comparing patients treated with selective decontamination with untreated controls. From eleven trials (1…

Average systolic blood pressure levels from epidemiological studies conducted on black populations in sub-Sahara Africa were pooled and compared with pooled systolic blood pressure levels from black populations in the northern portion of the Western hemisphere (the West Indies and the United States). Studies published…

Terazosin is a new, long-acting, selective, postsynaptic alpha 1-adrenergic receptor antagonist with a chemical structure similar to that of prazosin. In this article the pharmacokinetics of terazosin are reviewed, and the incidence of adverse events in a dose-response study and a meta-analysis of 20 placebo-controlled…

BACKGROUND: The complete and accurate identification of fatal occupational injuries among the US work force is an important first step in developing work injury prevention efforts. Numerous sources of information, such as death certificates, Workers' Compensation files, Occupational Safety and Health Administration (OS…

This analysis combines the results of the epidemiologic studies which appeared in the literature from 1979-1987 concerning the associations between phenoxy acid herbicides (PH) and chlorophenols (CP) and the occurrence of soft tissue sarcoma. Cohort studies and case-control studies are considered separately. After spec…

STUDY OBJECTIVE: Regional anesthesia techniques for traumatic rib fractures are rapidly being adopted by clinicians in emergency medicine to augment early pain management; however, the impact of "single-shot" techniques remains unclear. This systematic review and network meta-analysis was designed to identify the most…

INTRODUCTION: Cervical lesions often demand specialized approaches due to their anatomical position, and the effectiveness of these techniques may vary among clinicians. OBJECTIVES: To assess the clinical effectiveness of various adhesive strategies combined with different restorative materials for managing cavitated…

BACKGROUND: Ventral hernia repair is one of the most frequently performed surgical procedures worldwide, yet there is no consensus on the safest and most effective approach. This network meta-analysis aimed to evaluate the optimal surgical technique for ventral hernia repair. STUDY DESIGN: We systematically searched P…

BACKGROUND: The interim results of the Cardiac Arrhythmia Suppression Trial requires physicians to use a higher threshold for employing antiarrhythmic agents in the treatment of benign or potentially lethal ventricular arrhythmias. Many have managed patients by switching to the traditional class I quinidine despite its…

Since the relationship between oral contraceptive use and breast cancer has not been consistent we undertook a meta-analysis of studies published to date. Papers were located by searching the MEDLINE data base, supplemented by a hand search of all the references in the articles recovered. Studies were graded as to qual…

OBJECTIVE: Although studies have explored the analysis of acupuncture therapy in the treatment of cancer-related fatigue, there are still deficiencies in terms of the degree of fatigue, quality of life, and cancer-related indicators. The best option remains elusive regarding the degree of improvement in these aspects.…

BACKGROUND: As a therapeutic approach, physical activity can serve as a rehabilitation method for females with multiple sclerosis. However, the optimal exercise type remains unclear. This study aims to evaluate the effects of six distinct training programs on the physical function and psychological state of females wit…

CONTEXT: Women with functional hypothalamic amenorrhea (FHA) are at high risk of poor bone health. When lifestyle measures fail to restore menses, pharmacological interventions are needed for bone health, but comparative efficacy remains unclear. OBJECTIVE: To compare the efficacy of available pharmacological interven…

BACKGROUND AND AIMS: Among the newly established endoscopic submucosal dissection (ESD) techniques, underwater ESD (UW-ESD) using saline solution and traction-assisted ESD (T-ESD) aim to address the limitations of conventional ESD (C-ESD) for the resection of colorectal lesions. However, their comparative efficacy and…

BACKGROUND: Tranexamic acid (TXA) is widely used to reduce blood loss in spine surgery. Different administration routes, including intravenous (IV), topical, and oral, have been studied, but a comprehensive comparison of their efficacy and safety remains lacking. This network meta-analysis aims to compare the effective…