11,606,990 papers found

Sense of coherence (SOC) and mindfulness (MI) are believed to promote the health and well-being of individuals and organisations. The aim of this longitudinal study was to contribute to the literature on the development of SOC through training and interventions and thereby explore the development of these constructs in…

With the aging of the population, it is important to identify how other age groups perceive the elderly. The objective of this quantitative, cross-sectional and descriptive study was to evaluate the attitude of children living with seniors toward aging. Interviews were conducted with 54 children, aged between seven and…

The study's objectives were to assess the quality of life in Russian patients with epilepsy using the special QOLIE-31 questionnaire and to compare the findings obtained with those of similar foreign studies. Two hundreds and eight patients with epilepsy at the age 18-74 years (average duration of disease - 12.05 +/- 9…

OBJECTIVES: The paper identifies the central theoretical components for developing a typology of alcohol use with other substances. The settings and functions related to the simultaneous use of alcohol with marijuana or cocaine are examined using a dataset from a study of treatment clients in Ontario, Canada (data coll…

This study investigated 3 broad classes of individual-differences variables (job-search motives, competencies, and constraints) as predictors of job-search intensity among unemployed job seekers. Also assessed was the relationship between job-search intensity and reemployment success in a longitudinal context. Results…

Oligomeric alpha-synuclein (α-syn) in saliva and phosphorylated α-syn deposits in the skin have emerged as promising diagnostic biomarkers for Parkinson's disease (PD). This study aimed to assess and compare the diagnostic value of these biomarkers in discriminating between 38 PD patients and 24 healthy sub…

Philosophical frameworks are rarely made explicit in clinical research, yet they underlie decisions at every stage of study design. This technical report presents a case example of how a logical positivist epistemology, which emphasized observable data, inductive generalization, and methodological disinterestedness, wa…

BACKGROUND: Copy number variants (CNVs) play a key role in the etiology of autism spectrum disorder (ASD). Therefore, recent guidelines recommend chromosomal microarrays (CMAs) as first-tier genetic tests. This study's first aim was to determine the clinical usefulness of CMAs in children diagnosed with ASD in a Turkis…

Executive Functions (EF) exercise control over an individual's conduct and thinking through a set of functionally independent processes, among which are cognitive flexibility (reactive and spontaneous), working memory and planning. The development patterns of these components appear to have stages of acceleration and d…

BACKGROUND: While the p-value will tell the reader a study's results are statistically significant, it does not provide any information about the practical or clinical importance of the findings. Furthermore, p-values are influenced by sample size. They are more likely to be significant when sample size is large and le…

PURPOSE: To identify factors that can lead to corneal ectasia after laser in situ keratomileusis (LASIK). SETTING: University refractive surgery center. METHODS: In this retrospective study, the charts of all patients (2873 eyes) who had LASIK between May 1995 and November 1999 were reviewed. Fourteen patients (19 ey…

Scientific (research) misconduct relating to fraudulent behaviors, plagiarism, and violations in research protocol is extant in the literature. These behaviors result in inadvertent infringement on subjects' rights, safety, and confidentiality, and can negatively impact the implementation of health policies. Funding ag…

BACKGROUND: Stroke is a leading cause of death and disability worldwide, and there is still a lack of specific and sensitive biomarkers for its diagnosis. OBJECTIVE: This study aimed to investigate the diagnostic value of FOXO4 and Ep300 proteins in acute ischemic stroke patients who visited the emergency department.…

This study examined the association between social, psychological and physical well-being and a range of epilepsy-related and socio-demographic variables in a sample of people with epilepsy. A questionnaire method was used and the sample of 392 people with epilepsy was drawn from urban and rural epilepsy support groups…

Obstructive sleep apnea syndrome (OSAS) is a kind of sleep disturbance in which breathing is reduced or stopped for a short time and, if left untreated, can lead to long-term dangerous complications such as heart attack and obesity. Previous studies have shown that leptin receptor (LEPR) gene polymorphisms correlate wi…

BACKGROUND/AIM: The study's aim was to compare chromosome 3 aberrations of choroidal melanoma (CM) as determined by multiplex ligation dependent probe amplification (MLPA) or microsatellite analysis (MSA) in intraocular tumour biopsies with those results obtained from subsequent endoresection/enucleation of the same CM…

This brief communication is a response to the article "The prevalence of lisping in gay men" (Van Borsel, J., De Bruyn, E., Lefebvre, E., Sokoloff, A., De Ley, S., & Baudonck, N. 2009. Journal of Communication Disorders, 42, 100-106). I argue aspects of that study's design, measurement, and interpretation limit the str…

Venneman and colleagues argue that "do not resuscitate" (DNR) is problematic and should be replaced by "allow natural death" (AND). Their argument is flawed. First, while end-of-life discussions should be as positive as possible, they cannot and should not sidestep painful but necessary confrontations with morality. Se…

The relationship between adaptation to delayed auditory feedback (DAF) and oral sensory feedback as measured by tasks of oral form discrimination (OFD) was investigated. In addition, the interactions between OFD ability and attempts to heighten subjects' awareness of oral feedback while speaking under DAF conditions by…