11,367,428 papers found

BACKGROUND: There is a need to explore feasible means of accruing an appropriate study cohort to help fill the knowledge gap between pharmacogenetic contributions to drug response and clinical application in the pediatric population. OBJECTIVES: The aim of this study was to identify factors affecting recruitment of el…

OBJECTIVE: The objective was to analyse the associations of intensive care unit (ICU) and high care unit (HCU) organisational structure on in-hospital mortality among patients with sepsis in Japan's acute care hospitals. DESIGN: Multicentre cross-sectional study. SETTINGS: Patients with sepsis aged ≥18 years w…

BACKGROUND: According to the World Health Organization, dengue is among the top ten global health threats. The invasion of new sites byand their permanence depends on environmental characteristics of the site. Therefore, the objective was to understand the environmental characteristics that affectdistribution in C&#xf3…

BACKGROUND: Developing effective strategies to manage perioperative pain remains a focus of cleft care. The present study's purpose was to systematically review perioperative pain control strategies for cleft lip and palate repair. METHODS: A systematic review and meta-analysis of randomized controlled trials was perf…

PURPOSE: This study aimed to assess the impact of warm ischemia time on short-term renal function in individuals undergoing partial nephrectomy. METHODS: We conducted a comprehensive search for primary research articles from 1990 to October 15, 2024 across several databases, including MEDLINE, Embase and the Cochrane…

BACKGROUND: Over the past 5 years, the number of Vietnamese migrant workers in Japan has grown rapidly to become the largest group of migrant workers in the country. They hold various statuses of residence and are subjected to multifactorial stressors. AIMS: The current study's aim is to investigate the associa…

OBJECTIVES: Community Health Workers (CHWs) have been recommended to reduce diabetes disparities, but few robust trials of this approach have been conducted. Limitations of prior studies include: unspecified a priori outcomes; lack of blinded outcome assessments; high participant attrition rates; and lack of attention…

BACKGROUND: Hip osteoarthritis is a joint disease that causes  worsening pain and inhibits activities of daily living. Due to poor pain control and the function of usual clinical treatment, joint infiltration with orthobiologics is a therapeutic alternative. Among these, bone marrow aspirate (BMA) represents a cel…

Surgical intervention is an important option for treating lumbar tuberculosis. Previous studies have reported different surgical intervention procedures. To our knowledge, few studies have compared the clinical results of mid-term follow-up of 3 different surgeries in surgical treatment of spinal tuberculosis. This stu…

PURPOSE: To identify and assess diagnosis, procedure and pharmacy dispensing codes used to identify stillbirths and spontaneous abortion in administrative and claims databases from the United States or Canada. METHODS: We searched the MEDLINE database from 1991 to September 2012 using controlled vocabulary and key ter…

INTRODUCTION: Zinc oxide nanoparticles (ZnO NPs) exhibit a wide range of biomedical applications majorly used as antiinflammatory, anti-cancer, anti-diabetic, and anti-microbial activity and other biomedical applications because they show less toxicity and are very compatible. Zinc metal is an inorganic and essential e…

PURPOSE: To evaluate the long-term microtensile bond strength (µTBS) to dentin, water sorption (WSP) and solubility (WSL), and degree of conversion (DC) of self-adhesive resin composites (SACs). MATERIALS AND METHODS: The mid-coronal dentin of human molars was exposed, and teeth were randomly assigned to five gro…

COVID-19 has been widely explored in relation to its symptoms, outcomes, and risk profiles for the severe form of the disease. Our aim was to identify clusters of pregnant and postpartum women with severe acute respiratory syndrome (SARS) due to COVID-19 by analyzing data available in the Influenza Epidemiological Surv…

Plasminogen activator inhibitor-1 (PAI-1; SERPINE1) inhibits the plasminogen activators: tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). Elevated levels of PAI-1 have been correlated with an increased risk for cardiovascular disease. Pharmacologically suppressing PAI-1 might prev…

OBJECTIVE: To understand the perceptions of primiparous women recently diagnosed with Gestational Diabetes Mellitus (GDM) in Singapore. DESIGN: A descriptive qualitative study design. SETTING: An outpatient women's health clinic in a tertiary hospital in Singapore. PARTICIPANTS: Twelve English-speaking primiparous w…

OBJECTIVE:  The aim of this study was to systematically review literature on the use of iron supplements (not including iron derived from diet), increased levels of hemoglobin and/or ferritin, and the risk of developing gestational diabetes mellitus (GDM). DATA SOURCE:  The following databases were searc…

INTRODUCTION: COVID-19 pandemic has affected people all over the world. In this context, health disparities are already evident in becoming ill and dying from this condition, further accentuating historical racial inequalities. METHODS AND ANALYSIS: This protocol will be developed based on the recommendations of Prefe…

BACKGROUND: Controversy persists regarding continuous antibiotic prophylaxis (CAP) for vesicoureteral reflux (VUR) management. We sought to determine whether recent updates to the published literature continue to support the use of CAP in children with VUR. METHODS: We searched MEDLINE, EMBASE, Google Scholar, and Web…

BACKGROUND: Moral philosophical positions and professional values have been shown to influence nurses' practice behaviours. Understanding nursing students' professional values and ethical ideologies, therefore, is important as they may help inform evidence-informed curriculum decisions and education strategies to devel…