41,031 papers found

BACKGROUND: There are numerous reports worldwide on the use of complementary therapy for female infertility. This paper presents an overview of the available systematic reviews (SRs) on the outcomes of complementary therapy for female infertility. METHODS: Electronic databases, including Pubmed, the Cochrane Central R…

BACKGROUND: The aim of this study was to review the existing literature and evaluate whether deficits in set-shifting, central coherence and decision-making persist in individuals recovered from anorexia nervosa (AN-REC). METHOD: A systematic review approach was used. Literature was identified via searches in PubMed,…

OBJECTIVE: To investigate the use of applied kinesiology in the field of dentistry. METHODS: A review of the literature was carried out looking for all articles written on the topic. PubMed, Ovid Medline, and The Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched. RESULTS: Only one study…

Long-acting analogs of GnRH (GnRHas) have been the gold-standard treatment of central precocious puberty (CPP) worldwide and have an enviable track record of safety and efficacy. Recent years have witnessed much growth in the availability of longer-acting and sustained-release forms of GnRHas. Although all available ag…

The job of an editor is exciting, fraught with difficulties, friend-making, enemy-making, time-eating, time-saving, but above all, it is exciting. I took over from Jane Barlow in November 2018. First, I would like to thank her for her work. I do not just say this: Jane has made my work easy in many ways. She has steere…

BACKGROUND: Immune homeostasis plays a crucial role in immunology andis dependent on both central and peripheral tolerance. Centraltolerance and peripheral tolerance occur in the thymus and thesecondary lymphoid tissues, respectively. Tolerance breakdown andimmune regulation defects can lead to autoimmune disorders. In…

OBJECTIVE: The purpose of this study is to determine the application of thrombolytic treatment in central retinal artery occlusion (CRAO), its real benefit, safety and possible indications for treatment. METHODS: We searched the PubMed, Cochrane and Google Scholar databases delving first into the effectiveness of the…

Pathologies of central nervous system (CNS) functions are involved in prevalent conditions such as Alzheimer's disease, depression, and Parkinson's disease. Notable pathologies include dysfunctions of circadian rhythm, central metabolism, cardiovascular function, central stress responses, and movement mediated by the b…

BACKGROUND: The identification of biomarkers has led to the discovery of new pathways for precision diagnostics and tailored therapies in neoplasms of the central nervous system, thereby enhancing prognoses due to their diverse anatomical structures. OBJECTIVE: This review explores advancements in identifying biomarke…

Monoamine oxidase-A (MAO-A) is the main enzyme in the metabolism of the neurotransmitter serotonin (5-hydroxytryptamine). Elevated activity of MAO-A in the brain may contribute to the pathogenesis of depressive disorders. Plant flavonoids, such as flavonol quercetin and flavone luteolin, have been suggested to be poten…

INTRODUCTION: Recent advancements in artificial intelligence (AI) have introduced tools like ChatGPT-4, capable of interpreting visual data, including ECGs. In our study,we aimed to investigate the effectiveness of GPT-4 in interpreting ECGs and managing patient care in emergency settings. METHODS: Conducted from Apri…

UNLABELLED: Orbital fractures constitute a significant percentage of all midface injuries. Here, we present a contemporary evidence-based review of the major surgical approaches for orbital wall fractures and analyze the literature to compare all major surgical procedures and their complication rates. METHOD: A system…

We assessed adherence to five transparency practices-data sharing, code sharing, conflict of interest disclosure, funding disclosure, and protocol registration-in articles in dental journals. We searched and exported the full text of all research articles from PubMed-indexed dental journals available in the Europe PubM…

We conducted a systematic review to determine the efficacy and safety of cannabidiol (CBD) for chronic pain. The systematic review is according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 checklist. Five databases (PubMed, PubMed Central, Medline, Cochrane Library, and Science…

In pediatrics ultrasound has long been viewed more favorably than imaging that exposes patients to radiation and iodinated contrast or requires sedation. It is child-friendly and diagnostic capabilities have been improved with the advent of contrast-enhanced ultrasound (CEUS). The application of CEUS is indeed promisin…

With the advancement in basic and clinical sciences, medical education is also constantly evolving. The Accreditation Council for Graduate Medical Education (ACGME) has endorsed six core competencies to improve teaching and learning. This narrative review was conducted after searching the article databases (PubMed, Pub…

OBJECT: Cingulotomy has been reported in the literature as a potential treatment option for refractory cancer-related pain. However, the optimal candidates for this intervention and the outcomes are not well characterized. The goal of this study was to review the available literature on cingulotomy, specifically for ca…

OBJECTIVE: The objective of this review is to synthesize existing qualitative evidence on the experiences and perceptions of caregivers caring for children and adolescents with type 2 diabetes mellitus (T2D). INTRODUCTION: The rising number of new cases of T2D in children and adolescents highlights the urgent need for…

Alloplastic implants used in pelvic organ prolapse (POP) surgery can achieve good anatomical outcomes; however, concerns about complications such as vaginal wall erosion (VWE) have led to restrictions on their use. This systematic review and meta-analysis aimed to identify risk factors for VWE. A comprehensive search o…

PURPOSE: To investigate the effectiveness of different dosages of extracorporeal shockwave therapy (ESWT) on pain, function and radiographic outcomes in patients with osteonecrosis of femoral head (ONFH). PROCEDURE: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta Analysis) guidelines were followe…