11,352,860 papers found

This study examines variables that could predict treatment perseverance and impact for offenders (N = 124) admitted to one of five rehabilitation centers for alcoholics/drug addicts representing different regions of the province of Quebec. Information was collected on time spent in treatment, alcohol/drug use-related p…

OBJECTIVE: This study's objective was to prove or disprove four hypotheses, three addressing physical function and a subjective measure of self-perceived well-being from participating in an elder functional fitness program. METHODS: Participants included 17 chronically ill residents from an assisted-living center in M…

PURPOSE: Performance based measures have been suggested as an approach to estimate quality of life, but the associations have not been extensively evaluated. This study's purpose was to determine the associations between quality of life and performance based assessments of disablements in community dwelling individuals…

BACKGROUND: Labor and sex trafficking have long impacted the patients who seek care in emergency departments (ED) across the United States. Increasing social and legislative pressures have led to multiple calls for screening for trafficking in the clinical care setting, but adoption of unvalidated screening tools for t…

Studies of amyloid-β (Aβ) in Alzheimer's disease pathology have revealed the peptide's complex roles in synaptic function. The study by Siddu et al. in this issue clarifies the contexts in which Aβ peptides may be synaptogenic or synaptotoxic. This commentary integrates the study's major findings with…

BACKGROUND: The article by Martín-Domínguez V et al. proposes genetic testing as the first diagnostic test for lactose malabsorption, given its high concordance with the lactose breath test (LBT). We think that conceptual and methodological inconsistencies undermine this conclusion. METHODS: The genetic…

We read with great interest the recent meta-analysis by Dai et al. comparing the KangDuo (KD) and da Vinci (DV) robotic systems in radical prostatectomy (RP). Their findings highlight the comparable perioperative outcomes of both systems despite longer operative times with KD. While the study provides valuable insights…

This study's objective was to identify the prevalence of the American Health Information Management Association (AHIMA) career map jobs and determine which job categories, degrees, and skills are associated with higher pay. We extracted data from SimplyHired, a major employment website, from December 2018 to December 2…

Caregivers report experiences of stress and burden that can affect their health negatively. Web-based mindfulness interventions have shown beneficial health effects in clinical and non-clinical populations, including caregivers. The study's aim was to explore the experiences of a web-based mindfulness program, includin…

The Government of Bangladesh and WHO collaborated in a retrospective vaccine wastage study to estimate overall vaccine wastage rates from January to December 2004 for BCG, measles, DTP and TT. Researchers looked at vaccine distribution and usage patterns in randomly selected districts at both fixed (Upazila) and outrea…

Crime may be associated with a less structured society, less social integration, and feelings of less security and greater distress among citizens, which characteristics may lead to mental illness and subsequent suicide. Therefore, a cross-national analysis examining the association of general population suicide rates…

OBJECTIVE: Knowledge of distinct motivations and reasons toward or against future trial participation is invaluable to any organization conducting trial research. Study delays often occur due to lack of recruitment. This study's primary objective was to compare veteran and nonveteran motivations and reasons. METHODS:…

One goal of survey research is to optimize sampling procedures so that the collected data will produce accurate population estimates. In this context, sampling bias is a primary threat to a study's validity. If individuals who do not respond are a random sample of the population, then the estimates obtained from such a…

Scientifically trained and untrained judges read descriptions of an expert's research in which the peer review status and internal validity were manipulated. Seventeen percent of the judges said they would admit the expert evidence, irrespective of its internal validity. Publication in a peer-reviewed journal also had…

An experimental clinical study of angulatory and translational lumbar spine intervertebral motion was performed using flexion-extension radiographs obtained in the lateral plane. These "bending" films were obtained from 59 asymptomatic individuals undergoing routine pre-employment examination. Results indicate that the…

BACKGROUND: Recently, the literature on rural left-behind children in China has rapidly grown. However, no comprehensive review of the status of knowledge on the issue exists. METHODS: A co-cited network map of 327 studies (covering 1998 through 2014) drawn from the Chinese Social Studies Citation Index database was a…

BACKGROUND: Good access to primary care is an important determinant of population health. While the academic literature on access to care emphasises its complexity, policies aimed at improving access to general practice in the UK have tended to focus on measurable aspects, such as timeliness or number of appointments.…

The effect of brain damage on body temperature rhythm was investigated by spectral analysis using the maximum entropy method. The rectal temperatures of 56 patients with acute stroke were recorded for 1-3 days by actigraphy. Many patients with disturbance of consciousness showed infradian rhythm. Ambulatory patients te…

Alternative splicing of pre-mRNA is a key mechanism for increasing the complexity of proteins in humans, causing a diversity of expression of transcriptomes and proteomes in a tissue-specific manner. Alternative splicing is regulated by a variety of splicing factors. However, the changes and errors of splicing regulati…

Rigorous and reproducible methodology of controlling for bias is essential for high-quality, evidence-based studies. Propensity score matching (PSM) is a valuable way to control for bias and achieve pseudo-randomization in retrospective observation studies. The purpose of this review is to 1) provide a clear conceptual…