11,607,369 papers found

Bisphenol A, endocrine-disrupting chemicals (EDCs) impacting disease development via epigenetic modifications, is crucial in transcriptional regulation. However, ecotoxicology's limited exploration of epigenetics prompted our study's objective: examining the extended exposure of riverine Bisphenol A (BPA), a potent EDC…

Jette AM. The Post-Stroke Rehabilitation Outcomes Project. The Post-Stroke Rehabilitation Outcomes Project (PSROP) provides an important example of the value of observational study designs in rehabilitation. The strength of the PSROP lies in the extensive, in-depth data collected on the specific rehabilitation interven…

Social support has been linked to lower cardiovascular morbidity and mortality. However, most studies have examined perceived support as an intrapersonal construct. A dyadic approach to social support highlights how interdependence between individuals within relationships, including partner perceptions and interactions…

Implications for practice and research: Wong and colleagues' study improves on current risk stratification models for sepsis. The study's findings may lead to more homogeneous patient populations enrolled into clinical trials, increasing the chance of successful development of novel therapies for sepsis. There ar…

Therapeutic education for patients suffering from amyotrophic lateral sclerosis. A study to improve understanding of patients' needs after the diagnosis announcement as well as their therapeutic education was carried out at the Toulouse amyotrophic lateral sclerosis centre in 2010. In the light of the study's results,…

BACKGROUND AND OBJECTIVES: Cervical dilation measurement is difficult to teach. This pilot study's objective was to determine if residents participating in an innovative workshop improved their cervical measurement accuracy when using soft cervical models in the classroom. METHODS: Resident physicians measured cervica…

Since the inception of the MS Clinic, Vancouver Hospital and Health Sciences Centre, all consecutive, unrelated patients with multiple sclerosis (MS) have had their family histories documented by the Clinic's geneticist as part of the overall assessment. The family histories are updated annually. These data, along with…

This study's objective was to find out if HIV prevention program planners seek out science in designing interventions, and if not, where they turn for prevention information. Researchers conducted a survey of 284 program managers of AIDS prevention programs across the United States. Respondents' three most important so…

BACKGROUND AND OBJECTIVES: This study's objective was to evaluate the association between health literacy and human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) knowledge among patients seen at an inner-city, public hospital urgent care center (UCC). METHODS: We used a prospective survey of pat…

The purpose of this study was to determine how a group of institutionalized elderly Japanese women perceived animal-assisted activity (AAA) and how their perceptions may be relevant to clinical nursing practices in the AAA context. The participants in this study, 8 elderly Japanese women residing in a nursing home in a…

Much biomedical research is observational. The reporting of such research is often inadequate, which hampers the assessment of its strengths and weaknesses and of a study's generalizability. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Initiative developed recommendations on what sh…

OBJECTIVE: To determine whether in children born small for gestational age (SGA) high-dose growth hormone (GH) treatment is not only associated with catch-up of growth and with gain of lean mass, but also with a more central fat distribution. STUDY DESIGN: Short children who were SGA (n = 25; age [mean +/- SD], 5.3 +/…

This correspondence addresses the recent study by Xu et al. examining the relationship between the triglyceride-glucose (TyG) index and depression in older Chinese adults. The study's identification of a J-shaped association between TyG levels and depressive symptoms adds meaningful insight into the connection between…

OBJECTIVES: It is unknown if present-day pigments used for intrinsic colouration of maxillofacial prostheses are representative of human facial skin tones. This study's purpose was to measure L*a*b* values of pigmented elastomers coloured by eleven skin tone pigments and determine coverage error (CE) when the pigments…

The interactions between academic research and regulatory assessment of chemicals may in theory seem straightforward: researchers perform studies, and these studies are used by regulators for decision-making. However, in practice the situation is more complex, and many factors decide a research study's regulatory use.…

Patients who undergo laryngectomy typically lose their sense of smell. One device that has been used to rehabilitate olfactory function in these patients is the larynx bypass. We conducted a long-term study of the larynx bypass in 16 laryngectomized patients. After undergoing objective and subjective baseline evaluatio…

OBJECTIVE: Descriptive research was conducted for determining the level of knowledge (LK) held by people from Iribarren in the state of Lara, Venezuela, regarding influenza A (H1N1) 2009. METHODS: The population consisted of 1,800 people. The sample of 665 people was divided into groups: group 1 consisted of 300 high-…

OBJECTIVE: The aim: To define an ability to use pig as biomodel for experimental and clinical studies in order to develop new approaches of treatment of the rectal pathology. PATIENTS AND METHODS: Materials and methods: For the research two groups were used. I group includes 50 humans (27 females and 23 males), II gro…

PURPOSE: This paper presents the results of an online survey and subsequent interviews investigating whether, how, and why public administrations of Brazilian states and the federal district (Federation Units) use open government data. According to the literature reviewed, the questions were categorized into four big g…

RATIONALE: Animal studies of short-term progesterone administration and withdrawal model the natural increase and abrupt decrease in progesterone levels which occur in the late luteal phase (LP) of the human menstrual cycle (MC). Previously, studies in animals have shown that abrupt cessation of chronic or short-term p…