5,043,450 papers found

INTRODUCTION: Studies in recent years have shown that parental environmental experiences can affect their offspring's risk of breast cancer (BC). We assessed the effect of different paternal factors on BC risk in offspring by reviewing the existing literature. METHOD: This systematic review followed the Joanna Briggs…

In 2009, a multinational group of clinicians was charged with reviewing and evaluating the research base pertaining to incontinence-associated dermatitis (IAD) and synthesizing this knowledge into best practice recommendations based on existing evidence. This is the first of 2 articles focusing on IAD; it updates curre…

Hepatocelluar carcinoma (HCC) has rarely been associated with familial adenomatosis polyposis (FAP). Between 1950 and 2011, only a few cases of HCC associated with classic FAP have been reported in the medical literature. Here, we report the first case to our knowledge of HCC associated with attenuated FAP (aFAP). The…

Deep brain stimulation (DBS) is a neurosurgical treatment, which has proven useful in treating Parkinson's disease. This systematic review assessed the safety and effectiveness of DBS for another movement disorder, essential tremor. All studies concerning the use of DBS in patients with essential tremor were identified…

OBJECTIVE: The aim of this review is to increase understanding of the factors that affect the regular employment positions of people with epilepsy by means of the World Health Organization International Classification of Functioning, Disability, and Health (ICF) model. METHOD: Thirty-four primary research articles des…

Direct invasion of the central nervous system (CNS) occurs in 5% of all patients with non-Hodgkin's lymphoma, either at the time of presentation, as a solitary site of relapse, or during the course of progressive disease. Over the last several years, several studies, mostly retrospective, have analyzed risk factors ass…

OBJECTIVES: With the exponential growth of biomedical literature, the challenge of conducting systematic reviews is becoming increasingly burdensome. We aimed to evaluate the performance of large language models (LLMs) in the automation of some or all steps of systematic reviews and meta-analyses. STUDY DESIGN AND SET…

This article provided an overview of the strategies, tools, and techniques for searching the literature. Also discussed was how to retrieve, manage, and report relevant information that has been found. There are many books and computer tutorials about each of these topics available in libraries and bookstores. It may b…

This article summarises how evidence-based practice is defined, and what might constitute evidence. It describes the steps that should be taken in a systematic review of evidence, and some of the issues involved in implementing the findings of such reviews in practice.

AIM: This meta-review examined the incidence and prevalence rates of pressure ulcers in paediatric populations, to place in context the scope of the problem in this cohort of patients. The findings provide a foundation for future research on early factors contributing to paediatric pressure ulcers, aiming to improve un…

BACKGROUND: Fatigue and unintentional weight loss are two of the commonest symptoms experienced by people with advanced progressive illness. Appropriate interventions may bring considerable improvements in function and quality of life to seriously ill people and their families, reducing physical, psychological and spir…

Placental disorders remain one of the main causes of stillbirth. However, the lack of standardised nomenclature has significantly limited the clinical utility of placental histology. Following the Amsterdam consensus classification, which now allows proper comparisons of placenta histology across the world, we conducte…

BACKGROUND: The concept of stroke unit care has been discussed for over 50 years, but it is only in the last 25 years that clear evidence of its effectiveness has emerged to inform these discussions. SUMMARY: This review outlines the history of the concept of stroke units to improve recovery after stroke and their eva…

OBJECTIVE: To compare rapid reviews (RRs) to same-topic systematic reviews (SRs) for methods, studies included, and conclusions. STUDY DESIGN AND SETTING: A retrospective comparison of studies comparing RRs and SRs by searching four scoping reviews published between 2007 and 2016. Reports were included if literature s…

Transfusion medicine has become a large and complex specialty. Although there are now systematic reviews covering many aspects of transfusion, these span a large number of clinical areas and are published across more than a hundred different medical journals, making it difficult for transfusion medicine practitioners a…