2,695 papers found

The aim of this study is to systematically appraise the evidence on available full thickness 3D gingival and mucosal models (3D culture in scaffold base system) and their application in periodontal and peri-implant research. This study involved a systematic review of twenty-two studies obtained from searching from five…

OBJECTIVE: This study aims to evaluate the success rates and complications associated with different free flap donor sites used in surgical reconstruction for mandibular osteoradionecrosis, providing insights to aid clinical decision-making. DATA SOURCES: MEDLINE, Embase, Cochrane, and Web of Science. REVIEW METHODS:…

AIM: Code-free deep learning (CFDL) allows clinicians without coding expertise to build high-quality artificial intelligence (AI) models without writing code. In this review, we comprehensively review the advantages that CFDL offers over bespoke expert-designed deep learning (DL). As exemplars, we use the following tas…

OBJECTIVE: A systematic review (SR) was conducted to answer the following focused question based on PICO strategy: In patients who were submitted to harvesting palatal free gingival graft, could platelet-rich fibrin (PRF) application in comparison with another method improve the healing, pain, and control of postoperat…

INTRODUCTION: Use of indocyanine green (ICG) near-infrared fluorescence as a dye to assess tissue vascularization is now well standardized. The aim of this literature review was to review and resume the most recent recommendations for ICG use in its plastic surgery applications. METHODS: A systematic literature review…

BACKGROUND AND OBJECTIVES: To describe neurologist practice patterns, challenges, and decision support needs pertaining to withdrawal of antiseizure medications (ASMs) in patients with well-controlled epilepsy. METHODS: We sent an electronic survey to (1) US and (2) European physician members of the American Academy o…

BACKGROUND: Electronic health diaries hold promise in complementing standardized surveys in prospective health studies but are fraught with numerous methodological challenges. OBJECTIVE: The study aimed to investigate participant characteristics and other factors associated with response to an electronic health diary…

Aim This systematic review aimed to assess the effectiveness of fluoride varnish in preschool children for reducing the incidence of caries into dentine.Data sources Data came from published and grey literature. Databases searched were: CDSR, Medline, EMBASE, Web of Science, SCOPUS, LILACS and BBO. Hand-searching was d…

BACKGROUND: During and after general anaesthesia, opioids are commonly used for pain treatment. Since preclinical studies underlined the potential immunosuppressive activity of these drugs, it was postulated that their perioperative administration could influence cancer outcomes after surgery. Nevertheless, clinical da…

The decline of children's opportunities to play outdoors raises a new concern about the quality of outdoor play environments, and their developmental and well-being benefits for children. This systematic review aims to synthesize the associations between outdoor play features and children's behavior and health. PRISMA…

The purpose of this systematic review was to evaluate the potential benefits of antioxidant enrichment of semen extenders. These substances are used to combat oxidative stress during processing and conservation of rooster semen. A literature search was performed in June 2020 using the keywords rooster AND (semen OR spe…

Vascularized bone grafts (VBGs) are assumed to have advantages over non-VBGs, including preservation of cell viability and accelerated osteogenesis. Indications include the reconstruction of large bone defects, poor vascularity and previous radiation. However, clinical evidence supporting their superiority is limited.…

OBJECTIVE: Accurate and scalable dementia phenotyping from electronic health records (EHRs) is foundational for population-level research, risk prediction, and learning health system interventions. Traditional rule- and keyword-based approaches are limited by inconsistent documentation and inability to capture clinical…

Cognitive impairment affects multiple brain functions, and its early detection is essential to prevent progression to dementia; artificial intelligence has shown considerable potential in this field. This scoping review aims to map the impact of artificial intelligence-based tools for the early detection of cognitive i…

BACKGROUND: Hypertension during pregnancy is still the second leading cause of death in Indonesia. Most incidents are caused by delays in recognizing, bringing and taking appropriate action for pregnant women. This condition requires mutual awareness of both the mother and her family. One management that must be known…

INTRODUCTION: The COVID-19 pandemic has reinforced the need for digital transformation in health, bringing about the development of national strategies, new possibilities, but also challenges. The use of digital technologies and artificial intelligence enables accurate and personalized healthcare, while telenursing can…

Extended reality (XR) technology refers to any situation where real-world objects are enhanced with computer technology, including virtual reality, augmented reality, and mixed reality. Augmented reality and mixed reality technologies have been widely applied in orthopedic clinical practice, including in teaching, preo…

The mortality risk for individuals with pelvic fractures ranges from 10% to 50%, depending on the severity of the bleeding and the presence of concurrent brain, thorax, and abdomen injuries. This systematic review aims to comprehensively investigate the role of MRI and CT in diagnosing and managing pelvic fracture…

An aberrant growth of plasma cells in the bone marrow characterizes the hematological neoplasm known as multiple myeloma, which is typically accompanied by increased bone pain and skeletal-related events such as pathological fractures and/or spinal cord compression. Changes in the bone marrow microenvironment brought o…

Five major psychiatric disorders: schizophrenia, major depressive disorder, bipolar disorder, autistic spectrum disorder, and attention-deficit/hyperactivity disorder, show a shared genetic background and probably share common pathobiological mechanisms. S100B is a calcium-binding protein widely studied in psychiatric…