43,424 papers found

OBJECTIVE: To review the use of computed tomography (CT) and radiography in managing hepatic portal venous gas (HPVG) at a university-affiliated tertiary care center and in the literature. Hepatic portal venous gas is frequently associated with acute mesenteric ischemia, accounting for most of the HPVG-associated morta…

BACKGROUND: Hydrocephalus following intraventricular hemorrhage (IVH) is still one of the most serious complications of premature birth. Ventriculoperitoneal shunt surgery cannot be carried out early and permanent dependence on a shunt is associated with several serious complications. Streptokinase could be useful in t…

BACKGROUND: Black people have a greater prevalence of elevated blood pressure leading to excess morbidity and mortality. OBJECTIVES: To systematically review the effects of different antihypertensive drugs on mortality, morbidity and blood pressure black adults with elevated blood pressure. SEARCH STRATEGY: Medline,…

In recent years, there has been an exponential growth in global anti-cancer drug research, prompting the necessity for comprehensive analyses of publication output and thematic shifts.: This study utilized a comprehensive set of PubMed records from 1962 to 2024 and examined growth patterns, content classification, and…

OBJECTIVE: To evaluate the effectiveness of using a graft for reinforcement in rotator cuff repair compared to no use, as well as the effectiveness of different types of grafts, considering healing and shoulder function as primary outcomes, through a systematic review and meta-analysis of randomized controlled trials (…

Giant cell arteritis (GCA), a systemic vasculitis affecting large and medium-sized arteries, poses significant diagnostic and management challenges, particularly in preventing irreversible complications like vision loss. Recent advancements in artificial intelligence (AI) technologies, including machine learning (ML) a…

OBJECTIVES: To investigate whether exercise intervention is associated with reducing depressive symptoms in chronic kidney disease (CKD) patients. METHODS: Medline (PubMed), Web of Science, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) from inception to February 28, 2024. Randomized controll…

OBJECTIVES: Premature infants (born before 37 weeks of gestational age) frequently experience feeding difficulties due to underdeveloped oral motor skills and poor chewing, swallowing, and breathing coordination. In order to improve oral feeding efficiency in these infants, Oral-Motor Stimulation (OMS) has been used in…

OBJECTIVE: This review will assess the effectiveness of neuromuscular injury prevention strategies on injury rates among adolescent males playing sports. INTRODUCTION: Adolescent athletes are predisposed to injuries during this period of growth. Growth-related injury risk factors can be mitigated by implementing appro…

Pacing indications in children are clearly defined, but whether an epicardial (EPI) or an endocardial (ENDO) pacemaker performs better remains to be elucidated. This systematic review and meta-analysis aimed to directly compare the incidence of pacemaker (PM) lead-related complications, mortality, hemothorax and venous…

INTRODUCTION: Post-COVID-19 depression (PCD) is a possible sequela of COVID-19. Some doctors have used acupuncture to treat PCD, but no systematic review or meta-analysis has yet evaluated its efficacy and safety for the treatment of PCD. The aim of this systematic review is to assess the efficacy and safety of acupunc…

PURPOSE: To evaluate the efficacy of adjunctive aids to scaling and root planing (SRP) on clinical outcomes in treating periodontal patients included in regular periodontal maintenance programs. MATERIALS AND METHODS: The electronic databases MEDLINE (Pubmed), EMBASE, and the Cochrane Central Register of Controlled Tr…

BACKGROUND: Class III malocclusion is one the most challenging types of orthodontic problems. OBJECTIVES: The aim of this study was to compare the dentoskeletal effects of facemasks and intraoral appliances in treating class III maxillary deficiency in growing patients through a systematic review of the available lite…

The coronavirus disease of 2019 is a global pandemic disease severely affecting the upper respiratory tract that can be fatal in some instances. The virus most commonly affects the respiratory system. However, in certain cases it affects the other systems, including cardiovascular, renal, gastrointestinal, neurological…

This review aims to (i) summarize the literature on optogenetic applications of different stress-induced mood disorder models of the medial prefrontal cortex (mPFC) and its projection circuits, and (ii) examine methodological variability across the literature and how such variations may influence the underlying circuit…

OBJECTIVE: This review discusses the experimental and clinical studies those show the expression of connexin 36 in the central nervous system and the possible role of connexin 36 in epileptic seizure. DATA SOURCES: All articles used in this review were mainly searched from PubMed published in English from 1996 to 2012…

Noise-induced cochlear synaptopathy (CS) is defined as a permanent loss of synapses in the auditory nerve pathway following noise exposure. Several studies using auditory brainstem response (ABR) have indicated the presence of CS and increased central gain in tinnitus patients with normal hearing thresholds (TNHT), but…

Cardiovascular diseases (CVD) are now the number one cause of death in low- and middle-income countries, including those in Central Asia (CA). Low- and middle-income countries (LMICs) bear a disproportionate and growing burden of CVD, which constitutes a challenge to national development. CVD account for more than 43%…

Adults should get at least seven hours of sleep each night to preserve their overall health and well-being. Sleep disorders and other sleep-related issues affect a sizeable portion of the population. This reduction in sleep time may be brought on by the stress of modern life. This study's main goal was to look into the…

Delirium is a severe and variable neuropsychiatric illness that causes cognitive and behavioral problems as well as abrupt impairment in consciousness and focus. Due to the complex, dynamic, and multifaceted interactions between several risk factors, the etiology of delirium is unclear. Although its efficacy has n…